Tandem Repeated Application of Organic Solvents and Sodium Lauryl Sulphate Enhances Cumulative Skin Irritation

2014 ◽  
Vol 27 (3) ◽  
pp. 158-163 ◽  
Author(s):  
Sibylle Schliemann ◽  
Christina Schmidt ◽  
Peter Elsner
Toxicology ◽  
2017 ◽  
Vol 382 ◽  
pp. 10-15 ◽  
Author(s):  
Kotomi Horita ◽  
Daisuke Horita ◽  
Hiroyuki Tomita ◽  
Mitsue Yasoshima ◽  
Akiko Yagami ◽  
...  

1989 ◽  
Vol 21 (3) ◽  
pp. 184-188 ◽  
Author(s):  
Tove Agner ◽  
Jørgen Serup ◽  
Vagn Handlos ◽  
Walther Batsberg

2021 ◽  
Vol 5 (1) ◽  
pp. 1-7
Author(s):  
Sasidharan S ◽  

Pankajakasthuri orthoherb cream/thermagel is a polyherbal topical medication formulated for managing inflammation and pain. The objective of the present study was to evaluate the skin irritation potential of Pankajakasthuri orthoherb cream/thermagel on a single and repeated application in New Zealand white rabbits. The rabbits were dermally exposed with Pankajakasthuri orthoherb cream/thermagel and the appearance of each application site at 1 h, 24 h, 48 h, 72 h, 7th day and 14th day was recorded. The dermal reactions (erythema and edema) were evaluated according to the skin reactions scoring system. Pankajakasthuri orthoherb


2002 ◽  
Vol 146 (5) ◽  
pp. 777-785 ◽  
Author(s):  
I.L.A. Boxman ◽  
P.J. Hensbergen ◽  
R.C. Van Der Schors ◽  
D.P. Bruynzeel ◽  
C.P. Tensen ◽  
...  

1960 ◽  
Vol XXXV (I) ◽  
pp. 34-48 ◽  
Author(s):  
Gerd Ittrich

ABSTRACT A series of organic solvents and phenol derivatives have been examined for the extraction of the pink Kober-colour complex. Optimal results could be achieved for fluorimetry by a solution of 2 % (w/v) p-nitrophenol and 1 % (v/v) ethanol in acetylenetetrabromide, when the green mercury line (546 mμ was used as primary light. The sensitivity, stability and specificity have been improved, compared with the previously described reaction. By changing the sequence of purification steps and by reducing the volume of the urine sample (5 ml) the method for the determination of total oestrogens has been simplified. Approximately 10 determinations can be done within 3–4 hours by one person. Recovery experiments and comparative determinations with a previously described method have been carried out. The excretion of total oestrogens in a complete menstrual cycle is determined with the described method.


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