Duration of Untreated Illness and Duration of Illness in Anxiety Disorders: Assessment and Influence on Outcome

2013 ◽  
pp. 111-118 ◽  
Author(s):  
A. Carlo Altamura ◽  
Giulia Camuri ◽  
Bernardo Dell'Osso
Keyword(s):  
Anxiety Disorders ◽  
Duration Of Untreated Illness ◽  
Duration Of Illness

scholarly journals Duration of untreated psychiatric illness and its correlations in patients attending a tertiary care psychiatric facility: a cross-sectional study

2013 ◽  
Author(s):  
Swarna Buddha Nayok ◽  
Sathyanarayana MT ◽  
Dhanashree Akshatha H.S.
Keyword(s):  
Psychiatric Illness ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Psychiatric Facility ◽  
Cross Sectional ◽  
Duration Of Untreated Illness ◽  
Duration Of Illness ◽  
The Mean ◽  
Pathway To Care

Introduction: Duration of untreated psychiatric illness is an important component of the final pathway to care for patients. Longer the duration of untreated illness, poorer is the prognosis. Aim: To determine the Duration of Untreated Illness (DUI) along with its correlates, to thus evaluate the pathway to care at our setup. Settings and design: A retrospective cross-sectional study including 228 patients with psychiatric illnesses done at a tertiary care general hospital with a psychiatric setup. Materials: Semi-structured proforma for socio-demographic details, psychiatric diagnosis, duration of illness and duration of untreated illness. Statistical analysis: Sociodemographic details were mainly descriptive and categories compared using Pearson’s Chi square test. Results: The mean age of patients was 36.13 years (Standard Deviation (S.D.) 15.06). The mean DUI was 57.53 months (80.21). Excluding patients with Alcohol Dependence Syndrome (ADS), mean duration of illness was 51.58 months (S.D. 75.50) and DUI was 33.77 months (S.D. 49.11). Mean duration of illness for ADS group was 176.19 months (S.D. 101.20) and DUI was 165.90 months (S.D. 103.07). There was significant association of DUI with occupation (P = .039) and residence (P = .006). While 127 (55.70%) of patients showed to a psychiatrist at first, seventy (30.7%) patients went to faith healers first. Conclusion: It took about 5 years on average to reach a psychiatric facility, which was higher in patients with ADS. Awareness regarding illness model of ADS and other psychiatric disorders along treatment availability may improve DUI and lead to better prognosis.

Sensory processing disorders, duration of current episode, and severity of side effects in major affective and anxiety disorders

2016 ◽  
Vol 33 (S1) ◽  
pp. s224-s225
Author(s):  
G. Serafini ◽  
B. Engel-Yeger ◽  
G.H. Vazquez ◽  
M. Pompili ◽  
M. Amore
Keyword(s):  
Side Effects ◽  
Anxiety Disorders ◽  
Sensory Processing ◽  
Sensory Input ◽  
Sensory Sensitivity ◽  
Illness Duration ◽  
Medication Side Effects ◽  
Duration Of Untreated Illness ◽  
Medication Side ◽  
Sensory Processing Disorders

IntroductionLonger duration of untreated illness, longer duration of current episode, and severity of medication side effects may negatively influence the psychosocial functioning in major affective and anxiety disorders. Studies also suggested the involvement of sensory perception in emotional and psychopathological processes.ObjectiveThe objective of this study is to investigate the nature of the association between duration of untreated illness, duration of current episode, and severity of medication side effects.AimsThe study is aimed to examine the relationship between sensory processing disorders (SPD), duration of untreated illness, duration of current illness episode, and the severity of side effects related to psychoactive medications.MethodsThe sample included 178 participants with an age ranging from 17 to 85 years (mean = 53.84 ± 15.55); psychiatric diagnoses were as follow: unipolar major depressive disorder (MDD) (50%), bipolar disorder (BD) (33.7%), and anxiety disorders (16.3%). subjects completed a socio-demographic questionnaire, the Udvalg for Kliniske Undersøgelser (UKU), and Adolescent/Adult Sensory Profile (AASP) questionnaire.ResultsLonger duration of current episode correlated with greater registration of sensory input and lower avoidance from sensory input among unipolar patients, lower registration of sensory input, and higher tendency for sensory sensitivity/sensation avoidance among bipolar participants. In addition? longer duration of current episode correlated with lower sensory sensitivity/avoidance among anxiety participants, respectively. Mean UKU total scores were associated with lower sensory sensitivity among bipolar individuals as well.ConclusionsSPD expressed in either hypo-/hypersensitivity may be used to clinically characterize subjects with major affective and anxiety disorders.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Differences in duration of untreated illness, duration, and severity of illness among clinical phenotypes of obsessive-compulsive disorder

CNS Spectrums ◽  
2014 ◽  
Vol 20 (5) ◽  
pp. 474-478 ◽  
Author(s):  
Bernardo Dell’Osso ◽  
Beatrice Benatti ◽  
Lucio Oldani ◽  
Gregorio Spagnolin ◽  
A.Carlo Altamura
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Severity Of Illness ◽  
Comorbid Condition ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Clinical Phenotypes ◽  
Duration Of Untreated Illness ◽  
Multiple Phenotypes ◽  
Duration Of Illness ◽  
The Mean

IntroductionObsessive-compulsive disorder (OCD) is a prevalent, disabling, and comorbid condition that is frequently under-recognized and poorly treated. OCD phenotypes may differ in terms of clinical presentation and severity. However, few studies have investigated whether clinical phenotypes differ in terms of latency to treatment (ie, duration of untreated illness[DUI]), duration, and severity of illness. The present study was aimed to quantify the aforementioned variables in a sample of OCD patients.MethodsOne hundred fourteen outpatients with a Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision (DSM-IV-TR) diagnosis of OCD were recruited, and their main clinical features were collected. Severity of illness was assessed through the Yale–Brown Obsessive Compulsive Scale (Y-BOCS), and the main phenotypes were identified through the Y-BOCS Symptom Checklist. A one-way analysis of variance (ANOVA) test, followed by a Bonferroni post-hoc test, were performed to compare DUI, duration, and severity of illness across subgroups.ResultsIn the whole sample, the mean DUI exceeded 7 years (87.35±11.75 months), accounting for approximately half of the mean duration of illness (172.2±13.36 months). When subjects were categorized into 4 main clinical phenotypes, respectively, aggressive/checking (n=31), contamination/cleaning (n=37), symmetry/ordering (n=32), and multiple phenotypes (n=14), DUI, duration, and severity of illness resulted significantly higher in the aggressive/checking subgroup, compared to other subgroups (F=3.58, p<0.01; F=3.07, p<0.01; F=4.390, p<0.01).DiscussionIn a sample of OCD patients, along with a mean latency to treatment of approximately 7 years, regardless of the phenotype, patients had spent half of their duration of illness (DI) without being treated. DUI, duration, and severity of illness resulted significantly higher in the aggressive/checking subgroup.

Reduced duration of untreated illness over time in patients with schizophrenia spectrum, mood and anxiety disorders

2016 ◽  
Vol 70 (5) ◽  
pp. 202-210 ◽  
Author(s):  
Bernardo Dell'Osso ◽  
Lucio Oldani ◽  
Giulia Camuri ◽  
Beatrice Benatti ◽  
Benedetta Grancini ◽  
...  
Keyword(s):  
Anxiety Disorders ◽  
Duration Of Untreated Illness ◽  
Mood And Anxiety Disorders ◽  
Schizophrenia Spectrum ◽  
Over Time

Duration of Untreated Psychosis and Duration of Untreated Illness: New Vistas

CNS Spectrums ◽  
2010 ◽  
Vol 15 (4) ◽  
pp. 238-246 ◽  
Author(s):  
Bernardo Dell'Osso ◽  
A. Carlo Altamura
Keyword(s):  
Prognostic Factor ◽  
Anxiety Disorders ◽  
Psychotic Disorders ◽  
Duration Of Untreated Psychosis ◽  
Medline Search ◽  
Duration Of Untreated Illness ◽  
Mood And Anxiety Disorders ◽  
Negative Prognostic Factor ◽  
Clinical Consequences ◽  
Outcome Differences

ABSTRACTThe duration of untreated illness (DUI), defined as the interval between the onset of a psychiatric disorder and the administration of the first pharmacological treatment, has been increasingly investigated in the last decade as a predictor of outcome across different psychiatric conditions including schizophrenia and psychotic disorders (duration of untreated psychosis), and mood and anxiety disorders. Converging evidence indicates that a prolonged DUI may be viewed as a negative prognostic factor in schizophrenia and increasing data point toward a similar conclusion in mood and anxiety disorders. Through a Medline search, the present article highlights the role of the DUI in this group of psychiatric disorders, focusing on social and psychopathological determinants of the DUI, as well as the clinical consequences related to a longer DUI in terms of outcome. Hypotheses on neurobiological mechanisms underpinning outcome differences in relation to a prolonged DUI are provided and methodological limitations related to the assessment of the DUI in published studies and clinical practice discussed. Finally, given that DUI is supposed to be a potentially modifiable prognostic factor, intervention programs aimed to reduce this variable are briefly considered and discussed.

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