scholarly journals Cardiorenal Syndrome Type 4: Insights on Clinical Presentation and Pathophysiology from the Eleventh Consensus Conference of the Acute Dialysis Quality Initiative (ADQI)

Author(s):  
James A. Tumlin ◽  
Maria R. Costanzo ◽  
Lakhmir S. Chawla ◽  
Charles A. Herzog ◽  
John A. Kellum ◽  
...  
2011 ◽  
Vol 2011 ◽  
pp. 1-11 ◽  
Author(s):  
Dinna N. Cruz ◽  
Sean M. Bagshaw

Cardiac and kidney diseases are common, increasingly encountered, and often coexist. Recently, the Acute Dialysis Quality Initiative (ADQI) Working Group convened a consensus conference to develop a classification scheme for the CRS and for five discrete subtypes. These CRS subtypes likely share pathophysiologic mechanisms, however, also have distinguishing clinical features, in terms of precipitating events, risk identification, natural history, and outcomes. Knowledge of the epidemiology of heart-kidney interaction stratified by the proposed CRS subtypes is increasingly important for understanding the overall burden of disease for each CRS subtype, along with associated morbidity, mortality, and health resource utilization. Likewise, an understanding of the epidemiology of CRS is necessary for characterizing whether there exists important knowledge gaps and to aid in the design of clinical studies. This paper will provide a summary of the epidemiology of the cardiorenal syndrome and its subtypes.


2010 ◽  
Vol 21 (4) ◽  
pp. 357-364
Author(s):  
Shawn Merhaut ◽  
Robin J. Trupp

Left ventricular dysfunction and renal dysfunction are common chronic conditions that frequently coexist in the same individual, and both are associated with significant morbidity and mortality. Disorders in 1 organ generally lead to dysfunction in the other, and this bidirectional interaction serves as the pathophysiological basis for cardiorenal syndrome (CRS). Until recently, CRS has been neither well defined nor well understood, making its diagnosis and treatment challenging for clinicians. This article presents the pathophysiology of CRS and the new classification for types of CRS, therapeutic interventions targeting CRS, and novel therapies on the basis of the 2010 Acute Dialysis Quality Initiative consensus conference recommendations.


Critical Care ◽  
2014 ◽  
Vol 18 (Suppl 1) ◽  
pp. P364
Author(s):  
W Vandenberghe ◽  
S Gevaert ◽  
H Peperstraete ◽  
I Herck ◽  
J Decruyenaere ◽  
...  

2005 ◽  
Vol 28 (5) ◽  
pp. 441-444 ◽  
Author(s):  
J.A. Kellum ◽  
R. Bellomo ◽  
C. Ronco ◽  
R. Mehta ◽  
W. Clark ◽  
...  

Data in Brief ◽  
2018 ◽  
Vol 21 ◽  
pp. 1430-1434
Author(s):  
Giorgio Vescovo ◽  
Chiara Castellani ◽  
Marny Fedrigo ◽  
Grazia Maria Virzì ◽  
Giovanni Maria Vescovo ◽  
...  

PLoS ONE ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. e0190965 ◽  
Author(s):  
Saraschandra Vallabhajosyula ◽  
Ankit Sakhuja ◽  
Jeffrey B. Geske ◽  
Mukesh Kumar ◽  
Rahul Kashyap ◽  
...  

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