scholarly journals Soluble CD23 Levels are Inversely Associated with Atopy and Parasite-Specific IgE Levels but Not with Polyclonal IgE Levels in People Exposed to Helminth Infection

2013 ◽  
Vol 161 (4) ◽  
pp. 333-341 ◽  
Author(s):  
Nadine Rujeni ◽  
Norman Nausch ◽  
Nicholas Midzi ◽  
Reginald Gwisai ◽  
Takafira Mduluza ◽  
...  
Keyword(s):  
Helminth Infection ◽  
Specific Ige ◽  
Soluble Cd23

scholarly journals Increased plasma levels of soluble CD23 in haemorrhagic fever with renal syndrome; relation to virus-specific IgE

1997 ◽  
Vol 109 (2) ◽  
pp. 351-355 ◽  
Author(s):  
O. A. ALEXEYEV ◽  
M. LINDERHOLM ◽  
F. ELGH ◽  
G. WADELL ◽  
P. JUTO ◽  
...  
Keyword(s):  
Plasma Levels ◽  
Specific Ige ◽  
Haemorrhagic Fever ◽  
Soluble Cd23

scholarly journals Lack of Consistent Association between Asthma, Allergic Diseases and Intestinal Helminth Infection in School-Aged Children in the Province of Bengo, Angola

2021 ◽  
Vol 18 (11) ◽  
pp. 6156
Author(s):  
Margarete Arrais ◽  
Ofélia Lulua ◽  
Francisca Quifica ◽  
José Rosado-Pinto ◽  
Jorge M. R. Gama ◽  
...  
Keyword(s):  
Helminth Infection ◽  
Allergic Diseases ◽  
Specific Ige ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Intestinal Helminth ◽  
Cross Sectional ◽  
Positive Skin ◽  
Helminth Infections ◽  
The Relationship

Epidemiological studies have shown conflicting findings on the relationship between asthma, atopy, and intestinal helminth infections. There are no such studies from Angola; therefore, we aimed to evaluate the relationship between asthma, allergic diseases, atopy, and intestinal helminth infection in Angolan schoolchildren. We performed a cross-sectional study of schoolchildren between September and November 2017. Five schools (three urban, two rural) were randomly selected. Asthma, rhinoconjunctivitis, and eczema were defined by appropriate symptoms in the previous 12 months: atopy was defined by positive skin prick tests (SPT) or aeroallergen-specific IgE; intestinal helminths were detected by faecal sample microscopy. In total, 1023 children were evaluated (48.4% female; 57.6% aged 10–14 years; 60.5% urban). Asthma, rhinoconjunctivitis, or eczema were present in 9%, 6%, and 16% of the studies children, respectively. Only 8% of children had positive SPT, but 64% had positive sIgE. Additionally, 40% were infected with any intestinal helminth (A. lumbricoides 25.9%, T. trichiura 7.6%, and H. nana 6.3%). There were no consistent associations between intestinal helminth infections and asthma, allergic diseases, or atopy, except for A. lumbricoides, which was inversely associated with rhinoconjuctivitis and directly associated with aeroallergen-specific IgE. We concluded that, overall, intestinal helminth infections were not consistently associated with allergic symptoms or atopy. Future, preferably longitudinal, studies should collect more detailed information on helminth infections as part of clusters of environmental determinants of allergies.

Comparison between two automated systems to determine specific IgE: CAP and ELItest

1996 ◽  
Vol 26 (12) ◽  
pp. 1420-1427 ◽  
Author(s):  
T. BRUNNEE ◽  
A. SEEBERGER ◽  
J. KLEINE-TEBBE ◽  
G. KUNKEL
Keyword(s):  
Specific Ige ◽  
Automated Systems

CORRELATION OF SERUM SPECIFIC IGE AND SKIN PRICK TESTS IN CHILDREN WITH RESPIRATORY ALLERGY

2011 ◽  
Author(s):  
Esen Demir ◽  
Levent Midyat ◽  
Figen Gulen ◽  
Gulhadiye Akbas ◽  
Sema Tanrıverdi ◽  
...  
Keyword(s):  
Specific Ige ◽  
Respiratory Allergy ◽  
Skin Prick Tests

Component resolved diagnostics in peanut sensitized children with and without a history of clinical reaction

2020 ◽  
Vol 41 (5) ◽  
pp. 336-340
Author(s):  
Yasmin Hamzavi Abedi ◽  
Cristina P. Sison ◽  
Punita Ponda
Keyword(s):  
Retrospective Chart Review ◽  
Clinical History ◽  
Specific Ige ◽  
Exact Test ◽  
Ara H 1 ◽  
Sige Level ◽  
History Of ◽  
Laboratory Procedures ◽  
Ige Mediated ◽  
The Relationship

Background: Serum Peanut-specific-IgE (PN-sIgE) and peanut-component-resolved-diagnostics (CRD) are often ordered simultaneously in the evaluation for peanut allergy. Results often guide the plans for peanut oral challenge. However, the clinical utility of CRD at different total PN-sIgE levels is unclear. A commonly used predefined CRD Ara h2 cutoff value in the literature predicting probability of peanut challenge outcomes is 0.35kUA/L. Objective: To examine the utility of CRD in patients with and without a history of clinical reactivity to peanut (PN). Methods: This was a retrospective chart review of 196 children with PN-sIgE and CRD testing, of which, 98 patients had a clinical history of an IgE-mediated reaction when exposed to PN and 98 did not. The Fisher's exact test was used to assess the relationship between CRD and PN-sIgE at different cutoff levels, McNemar test and Gwet’s approach (AC1 statistic) were used to examine agreement between CRD and PN-sIgE, and logistic regression was used to assess differences in the findings between patients with and without reaction history. Results: Ara h 1, 2, 3, or 9 (ARAH) levels ≤0.35 kUA/L were significantly associated with PN-sIgE levels <2 kUA/L rather than ≥2 kUA/L (p < 0.0001). When the ARAH threshold was increased to 1 kUA/L and 2 kUA/L, these thresholds were still significantly associated with PN-sIgE levels of <2, <5, and <14 kUA/L. These findings were not significantly different in patients with and without a history of clinical reactivity. Conclusion: ARAH values correlated with PN-sIgE. Regardless of clinical history, ARAH levels are unlikely to be below 0.35, 1, or 2 kUA/L if the PN-sIgE level is >2 kUA/L. Thus, if possible, practitioners should consider PN-sIgE rather than automatically ordering CRD with PN-sIgE every time. Laboratory procedures that allow automatically and reflexively adding CRD when the PN-sIgE level is ≤5 kUA/L can be helpful. However, further studies are needed in subjects with challenge-proven PN allergy.

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