scholarly journals A Novel Anticancer Agent, SKLB70359, Inhibits Human Hepatic Carcinoma Cells proliferation via G0/G1 Cell Cycle Arrest and Apoptosis Induction

2012 ◽  
Vol 29 (1-2) ◽  
pp. 281-290 ◽  
Author(s):  
Xiao-Yun Dai ◽  
Xiu-Xiu Zeng ◽  
Feng Peng ◽  
Yuan-Yuan Han ◽  
Hong-Jun Lin ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Anticancer Agent ◽  
Carcinoma Cells ◽  
Apoptosis Induction ◽  
Hepatic Carcinoma ◽  
Cycle Arrest ◽  
G1 Cell Cycle Arrest

scholarly journals Induction of p53-Independent Apoptosis and G1 Cell Cycle Arrest by Fucoidan in HCT116 Human Colorectal Carcinoma Cells

Marine Drugs ◽  
2017 ◽  
Vol 15 (6) ◽  
pp. 154 ◽  
Author(s):  
Hye Park ◽  
Shin-Hyung Park ◽  
Jin-Woo Jeong ◽  
Dahye Yoon ◽  
Min Han ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Colorectal Carcinoma ◽  
Cell Cycle Arrest ◽  
Carcinoma Cells ◽  
Cycle Arrest ◽  
G1 Cell Cycle Arrest ◽  
Human Colorectal Carcinoma

scholarly journals Induction of G0/G1 cell cycle arrest in ovarian carcinoma cells by the anti-inflammatory drug NS-398, but not by COX-2-specific RNA interference

Oncogene ◽  
2003 ◽  
Vol 22 (54) ◽  
pp. 8653-8661 ◽  
Author(s):  
Carsten Denkert ◽  
Antje Fürstenberg ◽  
Peter Ted Daniel ◽  
Ines Koch ◽  
Martin Köbel ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Rna Interference ◽  
Ovarian Carcinoma ◽  
Cell Cycle Arrest ◽  
Carcinoma Cells ◽  
Inflammatory Drug ◽  
Cycle Arrest ◽  
Ovarian Carcinoma Cells ◽  
G1 Cell Cycle Arrest ◽  
Cox 2

scholarly journals EVALUATION OF THE ANTICANCER PROPERTIES OF TURMESAC® IN HUMAN CERVICAL ADENOCARCINOMA

2020 ◽  
pp. 109-113
Author(s):  
FIROZ HM ◽  
NANJUNDAIAH S ◽  
SADASHIVA CT
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Hela Cells ◽  
Anticancer Agent ◽  
Cervical Adenocarcinoma ◽  
Apoptosis Induction ◽  
Anticancer Properties ◽  
Cycle Arrest ◽  
Diphenyltetrazolium Bromide ◽  
Ic50 Value

Objective: In the current study, an extract of turmeric rhizome (Turmesac®) was evaluated for possible anticancer activity in human cervical adenocarcinoma (HeLa) cells. Methods: Turmesac®’s ability to elicit cytotoxicity in cancer cells was evaluated by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay (MTT) assay, where the IC50 value was determined. Apoptosis induction and cell cycle arrest were analyzed by flow cytometry post-Turmesac® IC50 value treatment for 24 h. Results: The determined IC50 value of Turmesac® in HeLa cells was 115.12 μg/ml. This concentration was able to induce apoptosis 2 times greater than the apoptotic standard, camptothecin, treated cells. Cell cycle arrest was observed at the G0/G1 and S phases in Turmesac® treated HeLa cells. Conclusion: Turmesac® shows the potential of being a promising anticancer agent that may be incorporated into chemotherapies, but further study is required to elucidate the exact mechanisms involved with longer treatment duration, as would be the case in clinical trial phases.

scholarly journals Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells

Cancer ◽  
2003 ◽  
Vol 98 (11) ◽  
pp. 2511-2520 ◽  
Author(s):  
Joann Zhang ◽  
Jocelyn C. Hsu B.A. ◽  
Matthew A. Kinseth B.A. ◽  
Leonard F. Bjeldanes ◽  
Gary L. Firestone
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Prostate Specific Antigen ◽  
Prostate Carcinoma ◽  
Specific Antigen ◽  
Carcinoma Cells ◽  
Antigen Production ◽  
Cycle Arrest ◽  
G1 Cell Cycle Arrest

Artesunate induces G0/G1 cell cycle arrest and iron-mediated mitochondrial apoptosis in A431 human epidermoid carcinoma cells

2012 ◽  
Vol 23 (6) ◽  
pp. 606-613 ◽  
Author(s):  
Zhongyong Jiang ◽  
Jin Chai ◽  
Henry Hon Fung Chuang ◽  
Shifeng Li ◽  
Tianran Wang ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Carcinoma Cells ◽  
Epidermoid Carcinoma ◽  
Mitochondrial Apoptosis ◽  
Cycle Arrest ◽  
G1 Cell Cycle Arrest ◽  
Human Epidermoid Carcinoma
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