A Risk-Adapted Strategy of Adjuvant Paclitaxel/Carboplatin in Early-Stage Ovarian Cancer: Time-Dependent Effect of 4 versus 6 Cycles on Outcome

Oncology ◽  
2011 ◽  
Vol 81 (5-6) ◽  
pp. 365-371 ◽  
Author(s):  
Aristotle Bamias ◽  
Christina Bamia ◽  
Alexandra Karadimou ◽  
Nikolaos Soupos ◽  
Flora Zagouri ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Early Stage ◽  
Time Dependent ◽  
Dependent Effect ◽  
Time Dependent Effect ◽  
Early Stage Ovarian Cancer

scholarly journals Comparison of the survival outcomes of laparoscopy versus laparotomy in treatment of early-stage ovarian cancer: a systematic review and meta-analysis

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Qingduo Kong ◽  
Hongyi Wei ◽  
Jing Zhang ◽  
Yilin Li ◽  
Yongjun Wang
Keyword(s):  
Ovarian Cancer ◽  
Overall Survival ◽  
Early Stage ◽  
Meta Analysis ◽  
Progression Free Survival ◽  
Cochrane Library ◽  
Survival Outcomes ◽  
Free Survival ◽  
Review Manager ◽  
Early Stage Ovarian Cancer

Abstract Background Laparoscopy has been widely used for patients with early-stage epithelial ovarian cancer (eEOC). However, there is limited evidence regarding whether survival outcomes of laparoscopy are equivalent to those of laparotomy among patients with eEOC. The result of survival outcomes of laparoscopy is still controversial. The aim of this meta-analysis is to analyze the survival outcomes of laparoscopy versus laparotomy in the treatment of eEOC. Methods According to the keywords, Pubmed, Embase, Cochrane Library and Clinicaltrials.gov were searched for studies from January 1994 to January 2021. Studies comparing the efficacy and safety of laparoscopy versus laparotomy for patients with eEOC were assessed for eligibility. Only studies including outcomes of overall survival (OS) were enrolled. The meta-analysis was performed using Stata software (Version 12.0) and Review Manager (Version 5.2). Results A total of 6 retrospective non-random studies were included in this meta-analysis. The pooled results indicated that there was no difference between two approaches for patients with eEOC in OS (HR = 0.6, P = 0.446), progression-free survival (PFS) (HR = 0.6, P = 0.137) and upstaging rate (OR = 1.18, P = 0.54). But the recurrence rate of laparoscopic surgery was lower than that of laparotomic surgery (OR = 0.48, P = 0.008). Conclusions Laparoscopy and laparotomy appear to provide comparable overall survival and progression-free survival outcomes for patients with eEOC. Further high-quality studies are needed to enhance this statement.

Time-dependent effect of an oral hypoglycemic agent upon serum glucose levels

1973 ◽  
Vol 10 (4) ◽  
pp. 841-851
Author(s):  
Juan J. Gagliardino ◽  
María T. Pessacq ◽  
Oscar Marcote ◽  
Elma E. Gagliardino
Keyword(s):  
Serum Glucose ◽  
Time Dependent ◽  
Oral Hypoglycemic Agent ◽  
Dependent Effect ◽  
Glucose Levels ◽  
Hypoglycemic Agent ◽  
Time Dependent Effect

Clinical Picture of Women with Early Stage Ovarian Cancer

2001 ◽  
Vol 81 (2) ◽  
pp. 337 ◽  
Author(s):  
Gamal H. Eltabbakh ◽  
Pramila R. Yadev ◽  
Ann Morgan
Keyword(s):  
Ovarian Cancer ◽  
Clinical Picture ◽  
Early Stage ◽  
Early Stage Ovarian Cancer
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