Development of Australian Reference Ranges for the Left Fetal Modified Myocardial Performance Index and the Influence of Caliper Location on Time Interval Measurement

2012 ◽  
Vol 32 (1-2) ◽  
pp. 87-95 ◽  
Author(s):  
N. Meriki ◽  
A.W. Welsh
Keyword(s):  
Performance Index ◽  
Myocardial Performance Index ◽  
Time Interval ◽  
Reference Ranges ◽  
Myocardial Performance ◽  
Interval Measurement ◽  
Time Interval Measurement

scholarly journals The Fetal Modified Myocardial Performance Index: Is Automation the Future?

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Priya Maheshwari ◽  
Amanda Henry ◽  
Alec W. Welsh
Keyword(s):  
Performance Index ◽  
Left Ventricular ◽  
Myocardial Performance Index ◽  
Time Interval ◽  
Reference Ranges ◽  
Myocardial Performance ◽  
Time Intervals ◽  
Measurement Variability ◽  
Cardiac Time Intervals ◽  
The Future

The fetal modified myocardial performance index (Mod-MPI) is a noninvasive, pulsed-wave Doppler-derived measure of global myocardial function. This review assesses the progress in technical refinements of its measurement and the potential for automation to be the crucial next step. The Mod-MPI is a ratio of isovolumetric to ejection time cardiac time intervals, and the potential for the left ventricular Mod-MPI as a tool to clinically assess fetal cardiac function is well-established. However, there are wide variations in published reference ranges, as (1) a standardised method of selecting cardiac time intervals used in Mod-MPI calculation has not been established; (2) cardiac time interval measurement currently requires manual, inherently subjective placement of callipers on Doppler ultrasound waveforms; and (3) ultrasound machine settings and ultrasound system type have been found to affect Mod-MPI measurement. Collectively these factors create potential for significant inter- and intraobserver measurement variability. Automated measurement of the Mod-MPI may be the next key development which propels the Mod-MPI into routine clinical use. A novel automated system of Mod-MPI measurement is briefly presented and its implications for the future of the Mod-MPI in fetal cardiology are discussed.

scholarly journals Turkish reference ranges for the left fetal modified myocardial performance index

2021 ◽  
Vol 63 (6) ◽  
pp. 1038
Author(s):  
Kadriye Yakut ◽  
Doğa Fatma Öcal ◽  
Filiz Öztürk ◽  
Merve Öztürk ◽  
Cem Yaşar Sanhal ◽  
...  
Keyword(s):  
Performance Index ◽  
Myocardial Performance Index ◽  
Reference Ranges ◽  
Myocardial Performance

scholarly journals Reference ranges of fetal heart function using a Modified Myocardial Performance Index: a prospective multicentre, cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e049640
Author(s):  
Lijuan Sun ◽  
Jingjing Wang ◽  
Xiaoting Su ◽  
Xinlin Chen ◽  
Yuqing Zhou ◽  
...  
Keyword(s):  
Performance Index ◽  
Cross Sectional Study ◽  
Left Ventricular ◽  
Myocardial Performance Index ◽  
Reference Ranges ◽  
Myocardial Performance ◽  
Sectional Study ◽  
Cross Sectional ◽  
Normal Reference ◽  
Singleton Pregnancies

ObjectivesThe primary aim of this study was to establish the normal reference ranges of the fetal left ventricular (LV) Modified Myocardial Performance Index (Mod-MPI). A secondary aim was to evaluate the agreement between manual and automatic measurements for fetal Mod-MPI.DesignA prospective, multicentre, cross-sectional study.ParticipantsNormal singleton pregnancies.MethodsThe LV functions of normal singleton pregnancies were assessed in nine centres covering eight provinces in China using unified ultrasound protocols and settings and standardised measurements by pulsed Doppler at 20–24, 28–32 and 34–38 weeks of gestation. The isovolumetric relaxation time (IRT), isovolumetric contraction time, ejection time (ET) and Mod-MPI were measured both automatically and manually.ResultsThis cross-sectional study included 2081 fetuses, and there was a linear correlation between gestational age (GA) and Mod-MPI (0.416+0.001×GA (weeks), p<0.001, r2=0.013), IRT (36.201+0.162× GA (weeks), p<0.001, r2=0.021) and ET (171.418–0.078*GA (weeks), p<0.001, r2=0.002). This finding was verified using longitudinal data in a subgroup of 610 women. The agreement between the manual and automated measurements for Mod-MPI was good.ConclusionsWe constructed normal reference values of fetal LV Mod-MPI. Automatic measurement can be considered for ease of measurement in view of the good agreement between the automatic and manual values.

scholarly journals The (Pulsed-Wave) Doppler Fetal Myocardial Performance Index: Technical Challenges, Clinical Applications and Future Research

2015 ◽  
Vol 38 (1) ◽  
pp. 1-13 ◽  
Author(s):  
Aditi Mahajan ◽  
Amanda Henry ◽  
Neama Meriki ◽  
Edgar Hernandez-Andrade ◽  
Fatima Crispi ◽  
...  
Keyword(s):  
Performance Index ◽  
Myocardial Performance Index ◽  
Future Research ◽  
Reference Ranges ◽  
Myocardial Performance ◽  
Cardiac Strain ◽  
Highly Sensitive ◽  
Cardiovascular Assessment ◽  
Pulsed Wave Doppler ◽  
Parameter Measuring

Functional cardiovascular assessment is becoming an increasingly important tool in the study of fetal pathology. The myocardial performance index (MPI) is a parameter measuring global myocardial function. Since its introduction, several studies have proposed methods to improve its reproducibility and have constructed normative reference ranges. Fetal heart evaluation using the MPI is technically challenging, requiring specific training and expertise, and a consensus has yet to be reached on the method of delineating the time periods used to calculate the index. Despite these limitations, it has been shown to be a useful and highly sensitive parameter of dysfunction in a number of fetal pathologies. Further research is warranted into the effect of pathology on MPI, parameters of unilateral cardiac strain that utilise MPI, and automation of the MPI to encourage incorporation of the MPI as a useful tool in clinical practice.

scholarly journals The evaluation of myocardial performance index in patients with COVID-19: An echocardiographic follow-up study

2021 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
H Kaya ◽  
R Asoglu ◽  
A Afsin ◽  
H Tibilli ◽  
E Kurt ◽  
...  
Keyword(s):  
Performance Index ◽  
Left Ventricular ◽  
Myocardial Performance Index ◽  
World Health ◽  
Time Interval ◽  
Intensive Care Treatment ◽  
Myocardial Performance ◽  
Clinical Recovery ◽  
Follow Up Study

Abstract Funding Acknowledgements Type of funding sources: None. Introduction The epidemic of pneumonia caused by a new coronavirus rapidly spread all over the world. World Health Organization called the condition as coronavirus disease 2019 (COVID-19). COVID-19 has become a life-threatening public health emergency internationally. COVID-19 mostly presents by respiratory tract symptoms including fever, dry cough, and dyspnea. The disease progression causes pneumonia and acute respiratory distress syndrome. Pathophisyology of cardiovascular effects of COVID-19 have not been well known yet. Myocardial dysfunction may occur in cytokine-originated immune reactions. Myocardial performance index (MPI) is a feasible parameter that reflects systolic and diastolic cardiac functions. Purpose We aimed to evaluate the MPI in patients with COVID-19. Methods The study consisted of 40 patients diagnosed with COVID-19 who had mild pneumonia and had not needed intensive care treatment. Transthoracic echocardiographic examination was performed in all patients at the acute stage of infection and after clinical recovery. The average time interval between the baseline and recovery echocardiography exam was about 28 ± 3,4 days. Blood samples were studied on day 0 and on days 7, 14, 21, and 28.  Immunofluorescence assay was used for COVID-19 antibody titers.  Respiratory secretions were sent for RT-PCR tests. Results The mean age was 54 ± 11 years ( male 26 (65% ) ). Statistically significant higher MPI (0.56 ± 0.09 versus 0.44 ± 0.07, p &lt; 0.001), longer isovolumic relaxation time (112.3 ± 13.4 versus 91.8 ± 12.1ms, p &lt; 0.001), longer deceleration time (182.1 ± 30.6 versus 161.5 ± 43.5ms, p = 0.003), shorter ejection time (279.6 ± 20.3 versus 298.8 ± 36.8ms, p &lt; 0.001) and higher E/A ratio (1.53 ± 0.7 versus  1.22 ± 0.4, p &lt; 0.001), were observed during acute period of  infection compared to ones after clinical recovery. Compared with basal values, no significant change in left ventricular systolic ejection fraction was observed after clinical recovery (60.3± 3.2% versus 61.7 ± 2.4%, p &gt; 0.05). Isovolumic contraction time was similar at acute infection and after clinical recovery ( 44.3 ± 7.8 versus 40.6 ± 9.7ms, p &gt; 0.05) Conclusion In conclusion, our study suggests global reversible LV dysfunction in COVID-19 patients with preserved LV systolic function based on tissue Doppler derived MPI. This could be due to isolated subclinical diastolic dysfunction. To our knowledge, this study is the first echocardiographic follow-up study that evaluated the systolic and diastolic function of the left ventricle in COVID -19 patients. The underlying mechanism and its clinical significance can be established by further studies.

Reference ranges of myocardial performance index from 12 to 40 weeks of gestation

2014 ◽  
Vol 290 (5) ◽  
pp. 859-865 ◽  
Author(s):  
Suchaya Luewan ◽  
Fuanglada Tongprasert ◽  
Kasemsri Srisupundit ◽  
Kuntharee Traisrisilp ◽  
Theera Tongsong
Keyword(s):  
Performance Index ◽  
Myocardial Performance Index ◽  
Reference Ranges ◽  
Myocardial Performance
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