Normal Reference Ranges from 11 to 41 Weeks’ Gestation of Fetal Left Modified Myocardial Performance Index by Conventional Doppler with the Use of Stringent Criteria for Delimitation of the Time Periods

2012 ◽  
Vol 32 (1-2) ◽  
pp. 79-86 ◽  
Author(s):  
R. Cruz-Martínez ◽  
F. Figueras ◽  
M. Bennasar ◽  
R. García-Posadas ◽  
F. Crispi ◽  
...  
BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e049640
Author(s):  
Lijuan Sun ◽  
Jingjing Wang ◽  
Xiaoting Su ◽  
Xinlin Chen ◽  
Yuqing Zhou ◽  
...  

ObjectivesThe primary aim of this study was to establish the normal reference ranges of the fetal left ventricular (LV) Modified Myocardial Performance Index (Mod-MPI). A secondary aim was to evaluate the agreement between manual and automatic measurements for fetal Mod-MPI.DesignA prospective, multicentre, cross-sectional study.ParticipantsNormal singleton pregnancies.MethodsThe LV functions of normal singleton pregnancies were assessed in nine centres covering eight provinces in China using unified ultrasound protocols and settings and standardised measurements by pulsed Doppler at 20–24, 28–32 and 34–38 weeks of gestation. The isovolumetric relaxation time (IRT), isovolumetric contraction time, ejection time (ET) and Mod-MPI were measured both automatically and manually.ResultsThis cross-sectional study included 2081 fetuses, and there was a linear correlation between gestational age (GA) and Mod-MPI (0.416+0.001×GA (weeks), p<0.001, r2=0.013), IRT (36.201+0.162× GA (weeks), p<0.001, r2=0.021) and ET (171.418–0.078*GA (weeks), p<0.001, r2=0.002). This finding was verified using longitudinal data in a subgroup of 610 women. The agreement between the manual and automated measurements for Mod-MPI was good.ConclusionsWe constructed normal reference values of fetal LV Mod-MPI. Automatic measurement can be considered for ease of measurement in view of the good agreement between the automatic and manual values.


2019 ◽  
Vol 34 (3) ◽  
pp. 456-465
Author(s):  
Alberto Borges Peixoto ◽  
Nathalie Jeanne Magioli Bravo-Valenzuela ◽  
Wellington P. Martins ◽  
Rosiane Mattar ◽  
Antonio Fernandes Moron ◽  
...  

2021 ◽  
Vol 63 (6) ◽  
pp. 1038
Author(s):  
Kadriye Yakut ◽  
Doğa Fatma Öcal ◽  
Filiz Öztürk ◽  
Merve Öztürk ◽  
Cem Yaşar Sanhal ◽  
...  

2015 ◽  
Vol 38 (1) ◽  
pp. 1-13 ◽  
Author(s):  
Aditi Mahajan ◽  
Amanda Henry ◽  
Neama Meriki ◽  
Edgar Hernandez-Andrade ◽  
Fatima Crispi ◽  
...  

Functional cardiovascular assessment is becoming an increasingly important tool in the study of fetal pathology. The myocardial performance index (MPI) is a parameter measuring global myocardial function. Since its introduction, several studies have proposed methods to improve its reproducibility and have constructed normative reference ranges. Fetal heart evaluation using the MPI is technically challenging, requiring specific training and expertise, and a consensus has yet to be reached on the method of delineating the time periods used to calculate the index. Despite these limitations, it has been shown to be a useful and highly sensitive parameter of dysfunction in a number of fetal pathologies. Further research is warranted into the effect of pathology on MPI, parameters of unilateral cardiac strain that utilise MPI, and automation of the MPI to encourage incorporation of the MPI as a useful tool in clinical practice.


2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Priya Maheshwari ◽  
Amanda Henry ◽  
Alec W. Welsh

The fetal modified myocardial performance index (Mod-MPI) is a noninvasive, pulsed-wave Doppler-derived measure of global myocardial function. This review assesses the progress in technical refinements of its measurement and the potential for automation to be the crucial next step. The Mod-MPI is a ratio of isovolumetric to ejection time cardiac time intervals, and the potential for the left ventricular Mod-MPI as a tool to clinically assess fetal cardiac function is well-established. However, there are wide variations in published reference ranges, as (1) a standardised method of selecting cardiac time intervals used in Mod-MPI calculation has not been established; (2) cardiac time interval measurement currently requires manual, inherently subjective placement of callipers on Doppler ultrasound waveforms; and (3) ultrasound machine settings and ultrasound system type have been found to affect Mod-MPI measurement. Collectively these factors create potential for significant inter- and intraobserver measurement variability. Automated measurement of the Mod-MPI may be the next key development which propels the Mod-MPI into routine clinical use. A novel automated system of Mod-MPI measurement is briefly presented and its implications for the future of the Mod-MPI in fetal cardiology are discussed.


2014 ◽  
Vol 290 (5) ◽  
pp. 859-865 ◽  
Author(s):  
Suchaya Luewan ◽  
Fuanglada Tongprasert ◽  
Kasemsri Srisupundit ◽  
Kuntharee Traisrisilp ◽  
Theera Tongsong

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