scholarly journals Factors Associated with Insulin Resistance among Children and Adolescents Perinatally Infected with HIV-1 in the Pediatric HIV/AIDS Cohort Study

2011 ◽  
Vol 76 (6) ◽  
pp. 386-391 ◽  
Author(s):  
Mitchell E. Geffner ◽  
Kunjal Patel ◽  
Tracie L. Miller ◽  
Rohan Hazra ◽  
Margarita Silio ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Cohort Study ◽  
Children And Adolescents ◽  
Pediatric Hiv ◽  
Factors Associated ◽  
Perinatally Infected ◽  
Hiv 1 ◽  
Hiv Aids

scholarly journals Prevalence and Factors Associated With Suicidal Ideation Among Children and Adolescents Attending a Pediatric HIV Clinic in Uganda

2021 ◽  
Vol 6 ◽  
Author(s):  
Justine Diana Namuli ◽  
Joyce Sserunjogi Nalugya ◽  
Paul Bangirana ◽  
Etheldreda Nakimuli-Mpungu
Keyword(s):  
Suicidal Ideation ◽  
Children And Adolescents ◽  
Pediatric Hiv ◽  
Parent Child Relationship ◽  
Child Exposure ◽  
Factors Associated ◽  
Wasting Syndrome ◽  
Child Relationship ◽  
Living With Hiv ◽  
Hiv Aids

Background: Suicidal behavior and HIV/AIDS are vital public health challenges especially in low and middle-income countries. As suicide in adults is perturbing for those closest to them, this sentiment is much more intense and generalized in the case of a child or adolescent. Knowledge of factors associated with suicidal ideation in HIV infected children and adolescents may inform suicide prevention strategies needed to improve their quality of life. This study aimed to assess the prevalence and factors associated with suicidal ideation among HIV infected children and adolescents attending a pediatric HIV clinic in Uganda.Methods: Data from a sample of 271 children and adolescents aged 6–18 years living with HIV/AIDS attending a pediatric HIV clinic was analyzed. Child characteristics and clinical variables were assessed using a socio-demographic questionnaire and medical records respectively. Suicidal ideation and depression were assessed using the Child Depression Inventory. The types of behavioral problems and the parent–child relationship were assessed using Child Behavioral Check List (6–18 years) and the Parent Child Relationship Scale respectively. Child exposure to different stressful life events was assessed with a series of standardized questions. Logistic regression models were used to explore factors independently associated with suicidal ideation.Results: The prevalence of suicidal ideation was 17%. In the multivariate analysis; Child exposure to family or friend’s death (prevalence rate ratio (PRR = 2.02; 95% CI, 1.01–4.03), p = 0.046), HIV wasting syndrome (PRR = 0.39; 95% CI, 0.21–0.75, p = 0.04), Depression (PRR = 1.08; 95% CI, 1.03–1.12, p = 0.001), Anxiety symptoms (PRR = 1.10; 95% CI, 1.01–1.20, p = 0.024) and Rule breaking behavior (PRR = 1.06; 95% CI, 0.99–1.13, p = 0.051) were independently associated with suicidal ideations.Conclusion: The prevalence of suicidal ideation among children and adolescents living with HIV/AIDS is substantial. Children and adolescents with exposure to family or friend’s death, those with higher depression scores, anxiety symptoms and rule breaking behavior are more likely to report suicidal ideation. Those with HIV wasting syndrome were less likely to report suicidal ideation. There is urgent need for HIV care providers to screen for suicide and link to mental health services.

scholarly journals Exposure to Violence and Virologic and Immunological Outcomes Among Youth With Perinatal HIV in the Pediatric HIV/AIDS Cohort Study

2016 ◽  
Vol 59 (1) ◽  
pp. 30-37 ◽  
Author(s):  
Deborah Kacanek ◽  
Kathleen Malee ◽  
Claude A. Mellins ◽  
Katherine Tassiopoulos ◽  
Renee Smith ◽  
...  
Keyword(s):  
Cohort Study ◽  
Exposure To Violence ◽  
Pediatric Hiv ◽  
Perinatal Hiv ◽  
Hiv Aids

Prevalence and Factors Associated With Virological Treatment Failure Among Children and Adolescents on Antiretroviral Therapy Attending HIV/AIDS Care and Treatment Clinics in Dodoma Municipality, Central Tanzania

2020 ◽  
Author(s):  
Niyonziza Z Bitwale ◽  
David P Mnzava ◽  
Francisca D Kimaro ◽  
Theopista Jacob ◽  
Bonaventura C T Mpondo ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Treatment Failure ◽  
Children And Adolescents ◽  
Virological Suppression ◽  
World Health ◽  
Hiv Status ◽  
Factors Associated ◽  
Current Prevalence ◽  
Virological Treatment Failure ◽  
Hiv Aids

Abstract Background As the World Health Organization (WHO) and its joint partners such as USAIDS target achieving 90% sustained virological suppression among children and adolescents living with Human Immunodeficience Virus (HIV)/AIDS, it is imperative to elucidate the current prevalence and factors associated with virological treatment failure for formulation of appropriate strategies. This study was conducted determine the prevalence and factors associated with virological treatment failure among children and adolescents with HIV/AIDS on antiretroviral therapy (ART) attending HIV/AIDS care clinics in Dodoma, Central Tanzania. Methods This was a cross-sectional study of children aged 1–19 years attending 3 HIV/AIDS care clinics in Dodoma (central Tanzania) from November 2018 to February 2019. Sociodemographic and clinical factors were documented, HIV viral load and CD4+ T lymphocytes were evaluated for children on ART for ≥6 months. The primary outcomes were the prevalence and factors associated with viralogic treatment failure. Results Of 300 children enrolled, 102 (34%) had virological treatment failure. Poor adherence to ART (adjusted odds ratio [AOR] = 3.221; 95% confidence interval [CI], 1.867–5.558; P = .032), nevirapine regimen (AOR = 3.185; 95% CI, 1.473–6.886; P ≤ .001), not using cotrimoxazole prophylaxis (AOR = 25.56; 95% CI, 3.15–27.55; P = .002) and nondisclosure of HIV status to others (AOR = 7.741; 95% CI, 2.351–25.489; P = .001) were independently associated with virological treatment failure. Conclusions Current prevalence of virological treatment failure among children and adolescents living with HIV on ART remain high. Factors such as ART adherence, nevirapine based regimen, HIV status disclosure to those caring for the child need to be addressed to achieve sustained virological suppression.

scholarly journals The impact of HAART on cardiomyopathy among children and adolescents perinatally infected with HIV-1

AIDS ◽  
2012 ◽  
Vol 26 (16) ◽  
pp. 2027-2037 ◽  
Author(s):  
Kunjal Patel ◽  
Russell B. Van Dyke ◽  
Murray A. Mittleman ◽  
Steven D. Colan ◽  
James M. Oleske ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Perinatally Infected ◽  
The Impact ◽  
Hiv 1

scholarly journals Oral Human Papillomavirus in Youth From the Pediatric HIV/AIDS Cohort Study

2016 ◽  
Vol 43 (8) ◽  
pp. 498-500 ◽  
Author(s):  
Anna-Barbara Moscicki ◽  
Sepideh Farhat ◽  
Tzy-Jyun Yao ◽  
Mark I. Ryder ◽  
Jonathan S. Russell ◽  
...  
Keyword(s):  
Cohort Study ◽  
Human Papillomavirus ◽  
Pediatric Hiv ◽  
Hiv Aids
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