Transgenic Overexpression of Tartrate-Resistant Acid Phosphatase Is Associated with Induction of Osteoblast Gene Expression and Increased Cortical Bone Mineral Content and Density

2012 ◽  
Vol 196 (1) ◽  
pp. 68-81 ◽  
Author(s):  
Per Gradin ◽  
Karin Hollberg ◽  
A. Ian Cassady ◽  
Pernilla Lång ◽  
Göran Andersson
Keyword(s):  
Gene Expression ◽  
Acid Phosphatase ◽  
Bone Mineral Content ◽  
Cortical Bone ◽  
Bone Mineral ◽  
Mineral Content ◽  
Tartrate Resistant Acid Phosphatase

Bone Metabolism, Bone Mineral Content, and Density in Elite Late Teen Female Sprinters

2021 ◽  
Author(s):  
Yuka Tsukahara ◽  
Suguru Torii ◽  
Fumihiro Yamasawa ◽  
Jun Iwamoto ◽  
Takanobu Otsuka ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Bone Mineral Content ◽  
Bone Metabolism ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Mineral Content ◽  
Whole Body ◽  
Tartrate Resistant Acid Phosphatase ◽  
Intensive Training ◽  
Turnover Markers

AbstractWith intensive training, bone injuries are a major concern for athletes. To assess bone condition, we often measure bone turnover markers, bone mineral content and density; however, in junior athletes, it is not easy to distinguish changes caused by bone injuries from those caused by growth, because the metabolism is increased in both cases. Moreover, although some studies have examined female endurance athletes, knowledge regarding changes in static and dynamic bone conditions in late teen athletes is limited. In this study, we measured the bone mineral content and density, as well as bone turnover markers, in 40 elite female sprinters in their late teens. Whole body mode dual-energy X-ray absorptiometry was performed to measure bone mineral content and density. Blood samples were collected to determine bone resorption and formation markers at the end of track season in 2016 and during the same period of the following year. Body weight and bone mineral content significantly increased, and tartrate-resistant acid phosphatase type 5b, bone-type alkaline phosphatase, and osteocalcin significantly decreased after a year. Furthermore, the rate of change in bone mineral content was higher in younger athletes, indicating that bone growth approaches completion in the late teen years and that bone metabolism accordingly decreases.

Intramedullary Nailing and Cortical Bone Mineral Content

1993 ◽  
Vol 34 (5) ◽  
pp. 464-467 ◽  
Author(s):  
Esko Kaartinen ◽  
L. Keskisaari ◽  
T. Holmström
Keyword(s):  
Bone Mineral Content ◽  
Cortical Bone ◽  
Intramedullary Nailing ◽  
Bone Mineral ◽  
Mineral Content

Altitude, pasture type, and sheep breed affect bone metabolism and serum 25-hydroxyvitamin D in grazing lambs

2013 ◽  
Vol 114 (10) ◽  
pp. 1441-1450 ◽  
Author(s):  
Helen Willems ◽  
Florian Leiber ◽  
Martina Kohler ◽  
Michael Kreuzer ◽  
Annette Liesegang
Keyword(s):  
Bone Mineral Content ◽  
Bone Metabolism ◽  
Cortical Bone ◽  
Bone Mineral ◽  
Mineral Content ◽  
Mineral Density ◽  
Hydroxyvitamin D ◽  
Alpine Pastures ◽  
25 Hydroxyvitamin D ◽  
Ca:P Ratio

This study aimed to investigate the bone development of two mountain sheep breeds during natural summer grazing either in the lowlands or on different characteristic alpine pastures. Pasture types differed in topographic slope, plant species composition, general nutritional feeding value, Ca and P content, and Ca:P ratio of herbage. Twenty-seven Engadine sheep (ES) lambs and 27 Valaisian Black Nose sheep (VS) lambs were divided into four groups of 6 to 7 animals per breed and allocated to three contrasting alpine pasture types and one lowland pasture type. The lambs were slaughtered after 9 wk of experimental grazing. The steep alpine pastures in combination with a high (4.8) to very high (13.6) Ca:P ratio in the forage decreased total bone mineral content as measured in the middle of the left metatarsus of the lambs from both breeds, and cortical bone mineral content and cortical bone mineral density of ES lambs. Breed × pasture type interactions occurred in the development of total and cortical bone mineral content, and in cortical thickness, indicating that bone metabolism of different genotypes obviously profited differently from the varying conditions. An altitude effect occurred for 25-hydroxyvitamin D with notably higher serum concentrations on the three alpine sites, and a breed effect led to higher concentrations for ES than VS. Despite a high variance, there were pasture-type effects on serum markers of bone formation and resorption.

Cortical bone mineral content in primary hyperparathyroidism. Changes after parathyroidectomy

1986 ◽  
Vol 111 (4) ◽  
pp. 494-497 ◽  
Author(s):  
Carlos Mautalen ◽  
Harry Romero Reyes ◽  
Gualterio Ghiringhelli ◽  
Günther Fromm
Keyword(s):  
Bone Loss ◽  
Primary Hyperparathyroidism ◽  
Bone Mass ◽  
Bone Mineral Content ◽  
Cortical Bone ◽  
Bone Mineral ◽  
Mineral Content ◽  
Significant Negative Correlation ◽  
Average Serum ◽  
Severe Degree

Abstract. The bone mineral content (BMC) of 35 patients with primary hyperparathyroidism (PHPT) was measured at the mid radius (95% cortical bone) by photon absorptiometry of a 241Am source. The majority of the patients had an overt disease of moderate to severe degree. Average serum calcium of the group was 12.3 mg/100 ml (range 10.6 to 18.0 mg/100 ml). The percentage of normality of the BMC was (Av ± 1 sd) 75.1 ± 13.0% for the whole group. The average increment of BMC in 14 patients 9 to 26 months after parathyroidectomy was 9.9%, with a wide dispersion. However a highly significant negative correlation (r: 0.83; P < 0.01) was found between the initial bone mass and the percentage increment per month after surgery. No further gain was observed 2 years after parathyroidectomy except in one patient with an extremely severe bone loss. In spite of the gain obtained after surgery the bone mass remained markedly diminished in most patients showing that the cortical bone loss caused by PHPT is mainly irreversible.

High-acceleration whole body vibration stimulates cortical bone accrual and increases bone mineral content in growing mice

2016 ◽  
Vol 49 (9) ◽  
pp. 1899-1908 ◽  
Author(s):  
Vasily Gnyubkin ◽  
Alain Guignandon ◽  
Norbert Laroche ◽  
Arnaud Vanden-Bossche ◽  
Luc Malaval ◽  
...  
Keyword(s):  
Bone Mineral Content ◽  
Cortical Bone ◽  
Bone Mineral ◽  
Mineral Content ◽  
Whole Body Vibration ◽  
Whole Body ◽  
Body Vibration ◽  
High Acceleration
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