‘Red Alert’ or Not? – Do We Give Our Inflammatory Bowel Disease Patients the Right Dietary Recommendations?

Digestion ◽  
2011 ◽  
Vol 84 (3) ◽  
pp. 236-237
Author(s):  
Gerhard Rogler
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Dietary Recommendations ◽  
Inflammatory Bowel ◽  
The Right

Current recommendations on the role of diet in the aetiology and management of IBD

2021 ◽  
pp. flgastro-2020-101429
Author(s):  
Konstantinos Gerasimidis ◽  
Lihi Godny ◽  
Rotem Sigall-Boneh ◽  
Vaios Svolos ◽  
Catherine Wall ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Disease Onset ◽  
Well Being ◽  
Disease Development ◽  
Dietary Recommendations ◽  
Exclusive Enteral Nutrition ◽  
Established Disease ◽  
Inflammatory Bowel

Diet is a key modifier of risk of inflammatory bowel disease development and potentially a treatment option in patients with established disease. International organisations in gastroenterology and inflammatory bowel disease have published guidelines for the role of diet in disease onset and its management. Here, we discuss the major overarching themes arising from these guidelines and appraise recent literature on the role of diet for inflammatory bowel disease prevention, treatment of active disease and maintenance of remission, considering these themes. Except for exclusive enteral nutrition in active Crohn’s disease, we currently possess very little evidence to make any further dietary recommendations for the management of inflammatory bowel disease. There is also currently uncertainty on the extrapolation of epidemiological dietary signals on risk of disease development and preclinical experiments in animal models to management, once disease is established. Until high-quality evidence from clinical research becomes available, the only specific recommendations for inflammatory bowel disease we might safely give are those of healthy eating which apply for the general population for overall health and well-being.

scholarly journals Finding the Right Index for Inflammatory Bowel Disease

1995 ◽  
Vol 9 (7) ◽  
pp. 397-400
Author(s):  
E Jan Irvine
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Subjective Symptoms ◽  
Markers Of Inflammation ◽  
Laboratory Markers ◽  
Study Population ◽  
Inflammatory Bowel ◽  
The Right ◽  
Activity Indices ◽  
The Ideal

Several activity indices have been developed to assess the efficacy of new therapies for inflammatory bowel disease. The ideal index should be simple to administer and quantitative. It should be a composite of subjective symptoms, objective findings and laboratory markers of inflammation. Any newly developed indices should be assessed for validity, reliability and responsiveness before application in clinical trials. Obstacles to standardizing disease activity relate to the heterogeneity of disease manifestations, the characteristics of the study population, the therapy being tested, the investigators' preference for which index to apply and the attributes of the index. Examples of available indices are identified, some of their limitations are discussed, and guidelines for how to select an index for a clinical trial are outlined.

scholarly journals Chronic cough in a patient with stable ulcerative colitis: a rare but important extraintestinal manifestation of inflammatory bowel disease

2019 ◽  
Vol 12 (1) ◽  
pp. bcr-2018-227066 ◽  
Author(s):  
Thomas Chad ◽  
Jeremy Brown
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Lower Lobe ◽  
Gas Transfer ◽  
Extraintestinal Manifestation ◽  
Sputum Production ◽  
Inflammatory Bowel ◽  
The Right

A 74-year-old woman presented to her general practitioner with cough and occasional sputum production. Having failed to respond to courses of antibiotics in the community, she was referred to the thoracic medicine clinic. High-resolution CT chest revealed cylindrical bronchiectasis predominantly in the right lower lobe. Lung function revealed preserved FEV1 and FVC but reduced gas transfer values. Bronchiectasis secondary to ulcerative colitis was diagnosed. Inhaled corticosteroid therapy was initiated, with good clinical response noted at 6 monthly follow-up. Remission was sustained with tapering of the steroid dose. Recognition of respiratory complications in cases of inflammatory bowel disease is likely still poor among clinicians. Although rare, a working knowledge of principles of investigation and management will aid timely diagnosis and treatment, potentially preventing progression of respiratory disease.

A Prospective Comparison of 99mTc-Labeled Polyclonal Human Immunoglobulin and 111In Granulocytes for Localization of Inflammatory Bowel Disease

1992 ◽  
Vol 33 (2) ◽  
pp. 140-144 ◽  
Author(s):  
J.-W. Arndt ◽  
Veer A. van der Sluys ◽  
D. Blok ◽  
G. Griffioen ◽  
H. W. Verspaget ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Intestinal Inflammation ◽  
Right Colon ◽  
Prospective Comparison ◽  
Intestinal Segments ◽  
Inflammatory Bowel ◽  
Low Sensitivity ◽  
The Right ◽  
Polyclonal Human Immunoglobulin

There is a need for an easily prepared radiopharmaceutical agent for the detection of inflammation and infection. In a group of 14 patients with inflammatory bowel disease (IBD), the detection of actively involved intestinal segments by nonspecific human polyclonal immunoglobulin (IgG) labeled with 99mTc was compared with that of 111In granulocytes. To determine the specificity of 99mTc-IgG scintigraphy, 8 control patients without clinical indications of intestinal inflammation were examined. 99mTc-IgG was found in the left colon in 8 and in the right colon in 7 of the 8 controls 4 hours after the injection. At that time of scintigraphy only 4 IBD patients exhibited a more intense accumulation at the site of the intestinal segments with active disease. In contrast, in a randomized comparison with 111In granulocytes scintigraphy was positive in 11 patients with the latter technique. Moreover, fewer diseased segments were seen in the 4 patients with positive 99mTc-IgG scintigraphy (6 versus 12 with 111In granulocytes). In view of the low sensitivity and specificity, it is concluded that 99mTc-IgG is not suitable for the scintigraphic staging of IBD patients.

scholarly journals Parental knowledge of chronic inflammatory bowel diseases in a child

2021 ◽  
Vol 26 (1) ◽  
pp. 30-34
Author(s):  
Leona Cilar ◽  
Špela Polak ◽  
Barbara Kegl
Keyword(s):  
Quality Of Life ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Chronic Inflammatory Bowel Disease ◽  
Care Providers ◽  
Inflammatory Bowel ◽  
The Right ◽  
The Impact ◽  
Chronic Inflammatory Bowel

Introduction: Chronic inflammatory bowel disease is a chronic lifelong disease with various triggers, intermediate longer and shorter remissions. Parents need to know what kind of nutrition the child with chronic inflammatory bowel disease needs because they must be able to make the right decisions regarding the child‘s diet. The right choice of diet gives a child enough energy in their daily and enables the quality life. They must enjoy a healthy balanced diet so that they receive all the nutrients the body needs. In our work, we presented chronic inflammatory bowel disease in children and parents’ assessment of the child’s quality of life. Methods: We chose a quantitative methodology to establish the impact of diet on the quality of life of the child with chronic inflammatory bowel disease. To describe and define the problem, we used a descriptive method. A structured measurement instrument was based on a review of the relevant foreign and domestic literature. Statistical data analysis was performed using descriptive and inferential statistics. Data were collected by a non-random and occasional sampling survey. Results: We found that most children whose parents participated in this research have Crohn’s disease (n = 20; 50%) and ulcerative colitis (n = 16; 40%). The type of food that is harmful to the child is fatty food (n = 33; 83%), followed by spicy food (n = 32; 80%) and acidic food (n = 10; 25%). According to the parents’ assessment, children with chronic inflammatory bowel disease have good (n = 22; 55%) health. We found that physicians provide parents with the most necessary nutrition information. Through evaluation of the parents, we found that there is no statistically significant correlation between the general assessment of a child’s health and the type of chronic inflammatory bowel disease (X² (2) = 5.925, p = 0.052). Also, there is no statistically significant correlation between the eating pattern and parents ’assessment of their child’s quality of life (U = 38.00, p. = 1.00). Discussion: The health care providers have an important role to play in giving appropriate information to parents to ensure the quality of life of the child. She teaches parents and children about living with chronic inflammatory bowel disease and emphasizes the importance of nutrition, which greatly contributes to a better quality of life.

Case 17.30

2014 ◽  
pp. 846-846
Author(s):  
Christine U. Lee ◽  
James F. Glockner
Keyword(s):  
Inflammatory Bowel Disease ◽  
Fundamental Frequency ◽  
Bowel Disease ◽  
Perianal Fistula ◽  
Larmor Frequency ◽  
Receiver Coil ◽  
Phase Encoding ◽  
Inflammatory Bowel ◽  
The Right

19-year-old woman with inflammatory bowel disease and suspected perianal fistula Axial postgadolinium 2D SPGR image (Figure 17.30.1) demonstrates a prominent artifact extending across the right side of the pelvis along the phase encoding direction. Zipper artifact Zipper artifacts most often occur as a result of a frequency leak—this is just extraneous RF radiation detected by the receiver coil. Notice that the line of artifact is off-center, indicating that the fundamental frequency is different from the Larmor frequency of the MRI system, which is what you would expect from an extraneous source....

scholarly journals A Case of Intestinal Mastocytosis Misdiagnosed as Crohn's Disease

2015 ◽  
Vol 9 (2) ◽  
pp. 188-193 ◽  
Author(s):  
Stefania Reggiani ◽  
Loretta Cosso ◽  
Alessandro Adriani ◽  
Stefano Pantaleoni ◽  
Alessandro Risso ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Progressive Disease ◽  
Systemic Mastocytosis ◽  
Gastrointestinal Symptoms ◽  
Poor Response ◽  
Skin Lesions ◽  
Surgical Specimen ◽  
Inflammatory Bowel ◽  
The Right

Systemic mastocytosis (SM) is a rare, heterogeneous and progressive disease, characterized by the accumulation of atypical mast cells in various organs, including the gastrointestinal tract. Gastrointestinal symptoms are present in up to 80% of patients with SM, the most common being abdominal pain, diarrhea, nausea and vomiting. Up to 50% of patients with SM do not have classical skin lesions at presentation, and in these patients the diagnosis of SM can be difficult for years. Here we report a case of SM that initially mimicked inflammatory bowel disease, although the patient showed poor response to steroid therapy. The right diagnosis was made only on the surgical specimen obtained after emergency surgery for intestinal obstruction. SM should therefore be considered in the diagnostic approach in patients with gastrointestinal symptoms not attributable to other pathologies and in cases of suspected inflammatory bowel disease with unusual course.

Serrated Lesions in Inflammatory Bowel Disease: Genotype-Phenotype Correlation

2020 ◽  
pp. 106689692096379
Author(s):  
Iva Brcic ◽  
Heather Dawson ◽  
Hans Peter Gröchenig ◽  
Christoph Högenauer ◽  
Karl Kashofer
Keyword(s):  
Inflammatory Bowel Disease ◽  
Molecular Analysis ◽  
Bowel Disease ◽  
Low Grade ◽  
Right Colon ◽  
Kras Mutations ◽  
Increased Risk ◽  
Serrated Lesions ◽  
Inflammatory Bowel ◽  
The Right

Background Patients with inflammatory bowel disease (IBD) and hyperplastic/serrated polyposis have an increased risk of colorectal cancer. The aim of our study was to elucidate the nature of serrated lesions in IBD patients. Materials and Methods Sixty-five lesions with serrated morphology were analyzed in 39 adult IBD patients. Lesions were classified according to the WHO 2019 criteria or regarded as reactive, and molecular analysis was performed. Results 82.1% of patients had ulcerative colitis, 17.9% had Crohn’s disease; 51.3% were female, and the mean age was 54.5 years. The duration of IBD varied significantly (16.7 ± 11.4 years). Endoscopy showed polypoid lesions in 80.3%; the size ranged from 2 to 20 mm. A total of 21.6% of the lesions were located in the right colon. Five lesions were classified as inflammatory pseudopolyps, 28 as hyperplastic polyp, 21 and 2 as sessile serrated lesion without and with dysplasia, respectively, and 9 as traditional serrated adenoma with low-grade dysplasia. Analysis of all true serrated lesions revealed 31 mutations in KRAS and 32 in BRAF gene. No mutations were identified in inflammatory pseudopolyps. In the right colon BRAF mutations were more frequent than KRAS (16 vs 3), while KRAS mutations prevailed on the left side (28 vs 16, P < .001). One patient with traditional serrated adenomas progressed to an adenocarcinoma after 61 months. Conclusion The molecular analysis could help discriminate true serrated lesions (IBD-associated or not) from reactive pseudopolyps with serrated/hyperplastic epithelial change. These should help in more accurate classification of serrated lesions.

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