Validity of the Mattis Dementia Rating Scale to Detect Mild Cognitive Impairment in Parkinson’s Disease and REM Sleep Behavior Disorder

2011 ◽  
Vol 31 (3) ◽  
pp. 210-217 ◽  
Author(s):  
Sylvia Villeneuve ◽  
Jessica Rodrigues-Brazète ◽  
Steve Joncas ◽  
Ronald B. Postuma ◽  
Véronique Latreille ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Rem Sleep ◽  
Rating Scale ◽  
Rem Sleep Behavior Disorder ◽  
Behavior Disorder ◽  
Sleep Behavior ◽  
Mattis Dementia Rating Scale ◽  
Dementia Rating Scale

REM sleep behavior disorder, hallucinations, and cognitive impairment in Parkinson's disease

2005 ◽  
Vol 21 (4) ◽  
pp. 462-466 ◽  
Author(s):  
Elena Sinforiani ◽  
Roberta Zangaglia ◽  
Raffaele Manni ◽  
Silvano Cristina ◽  
Enrico Marchioni ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Rem Sleep ◽  
Rem Sleep Behavior Disorder ◽  
Behavior Disorder ◽  
Sleep Behavior

The utility of the Mattis Dementia Rating Scale in Parkinson's disease mild cognitive impairment

2014 ◽  
Vol 20 (6) ◽  
pp. 627-631 ◽  
Author(s):  
Eva Pirogovsky ◽  
Dawn M. Schiehser ◽  
Irene Litvan ◽  
Kristalyn M. Obtera ◽  
Mathes M. Burke ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Rating Scale ◽  
Mattis Dementia Rating Scale ◽  
Dementia Rating Scale

Electroencephalographic slowing heralds mild cognitive impairment in idiopathic REM sleep behavior disorder

2010 ◽  
Vol 11 (6) ◽  
pp. 534-539 ◽  
Author(s):  
Alex Iranzo ◽  
Valentina Isetta ◽  
Jose Luis Molinuevo ◽  
Monica Serradell ◽  
Daniel Navajas ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Rem Sleep ◽  
Rem Sleep Behavior Disorder ◽  
Behavior Disorder ◽  
Sleep Behavior

scholarly journals Preliminary finding of a randomized, double-blind, placebo-controlled, crossover study to evaluate the safety and efficacy of 5-hydroxytryptophan on REM sleep behavior disorder in Parkinson’s disease

2021 ◽  
Author(s):  
Mario Meloni ◽  
Michela Figorilli ◽  
Manolo Carta ◽  
Ludovica Tamburrino ◽  
Antonino Cannas ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Rem Sleep ◽  
Rating Scale ◽  
Sleep Onset ◽  
Rem Sleep Behavior Disorder ◽  
Behavior Disorder ◽  
Double Blind ◽  
Sleep Behavior ◽  
Double Blind Placebo

Abstract Purpose Altered serotonergic neurotransmission may contribute to the non-motor features commonly associated with Parkinson’s disease (PD) such as sleep disorders. The 5-hydroxytryptophan (5-HTP) is the intermediate metabolite of l-tryptophan in the production of serotonin and melatonin. The purpose of this study was to compare the effects of 5-HTP to placebo on REM sleep behavior disorder (RBD) status in patients with PD. Methods A single-center, randomized, double-blind placebo-controlled crossover trial was performed in a selected population of 18 patients with PD and RBD. The patients received a placebo and 50 mg of 5-HTP daily in a crossover design over a period of 4 weeks. Results 5-HTP produced an increase in the total percentage of stage REM sleep without a related increase of RBD episodes, as well as a marginal, non-significant reduction in both arousal index and wake after sleep onset. The self-reported RBD frequency and clinical global impression (CGI) were improved during 5-HTP and placebo treatment in comparison to baseline. 5-HTP significantly improved our patients’ motor experiences of daily living as rated by the Unified Parkinson’s Disease Rating Scale (UPDRS) part II. Conclusions This study provides evidence that 5-HTP is safe and effective in improving sleep stability in PD, contributing to ameliorate patients’ global sleep quality. Larger studies with higher doses and longer treatment duration are needed to corroborate these preliminary findings.

The fate of patients with REM sleep behavior disorder and mild cognitive impairment

2020 ◽  
Author(s):  
Dario Arnaldi ◽  
Andrea Chincarini ◽  
Fabrizio De Carli ◽  
Francesco Famà ◽  
Nicola Girtler ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Rem Sleep ◽  
Rem Sleep Behavior Disorder ◽  
Behavior Disorder ◽  
Sleep Behavior

[P1-483]: LONGITUDINAL PERFORMANCE ON THE KING DEVICK TEST IN PATIENTS WITH REM SLEEP BEHAVIOR DISORDER +/- MILD COGNITIVE IMPAIRMENT

2017 ◽  
Vol 13 (7S_Part_9) ◽  
pp. P474-P474
Author(s):  
Angelica R. Boeve ◽  
Paul C. Timm ◽  
Siri V. McCord ◽  
David J. Sandness ◽  
Stuart J. McCarter ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Rem Sleep ◽  
Rem Sleep Behavior Disorder ◽  
Behavior Disorder ◽  
Sleep Behavior

The Montreal Cognitive Assessment: A screening tool for mild cognitive impairment in REM sleep behavior disorder

2010 ◽  
Vol 25 (7) ◽  
pp. 936-940 ◽  
Author(s):  
Jean-François Gagnon ◽  
Ronald B. Postuma ◽  
Steve Joncas ◽  
Catherine Desjardins ◽  
Véronique Latreille
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Rem Sleep ◽  
Cognitive Assessment ◽  
Screening Tool ◽  
Rem Sleep Behavior Disorder ◽  
Behavior Disorder ◽  
Montreal Cognitive Assessment ◽  
Sleep Behavior

scholarly journals REM Sleep Behavior Disorder and Cognitive Impairment in Parkinson’s Disease

SLEEP ◽  
2017 ◽  
Vol 40 (8) ◽  
Author(s):  
Natalia Jozwiak ◽  
Ronald B Postuma ◽  
Jacques Montplaisir ◽  
Véronique Latreille ◽  
Michel Panisset ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Rem Sleep ◽  
Rem Sleep Behavior Disorder ◽  
Behavior Disorder ◽  
Sleep Behavior

Clinical Validity of the Mattis Dementia Rating Scale in Differentiating Mild Cognitive Impairment in Parkinson's Disease and Normative Data

2015 ◽  
Vol 39 (5-6) ◽  
pp. 303-311 ◽  
Author(s):  
Ondrej Bezdicek ◽  
Jiri Michalec ◽  
Tomas Nikolai ◽  
Petra Havránková ◽  
Jan Roth ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Normative Data ◽  
Rating Scale ◽  
Mattis Dementia Rating Scale ◽  
Level Ii ◽  
Dementia Rating Scale ◽  
Level I

Background/Aims: The aim of the present study was to provide normative data and determine the validity of the Czech version of the Mattis Dementia Rating Scale 2 (czDRS-2) in screening for mild cognitive impairment in Parkinson's disease (PD-MCI) based on the Movement Disorder Society (MDS) Level II criteria. Methods: For validation purposes, 41 healthy controls (HC), 46 patients with PD-NI (Parkinson's disease, no impairment) and 41 patients with PD-MCI (all groups assessed by the MDS Level II criteria for PD-MCI) were matched according to age and education. Results: With screening and diagnostic cutoff scores determined at ≤139 points, the czDRS-2 showed a sensitivity of 78% and a specificity of 88% in the detection of PD-MCI versus HC and a sensitivity of 78% and a specificity of 76% in the detection of PD-MCI versus PD-NI. The AUC (95% confidence interval) for the czDRS-2 was 84% (75-93) and 82% (73-91), respectively. We report percentile values for 286 subjects from the Czech population stratified by education level. Conclusion: Our results show that the czDRS-2 is a valid instrument at Level I for screening PD-MCI and support its construct validity and diagnostic equivalence in a cross-cultural setting.

Prospective memory in idiopathic REM sleep behavior disorder with or without mild cognitive impairment: A preliminary study

2018 ◽  
Vol 33 (3) ◽  
pp. 571-593 ◽  
Author(s):  
Sonia Marcone ◽  
Jean-François Gagnon ◽  
Catherine Desjardins ◽  
Annie-Claude David ◽  
Ronald B. Postuma ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Prospective Memory ◽  
Rem Sleep ◽  
Rem Sleep Behavior Disorder ◽  
Behavior Disorder ◽  
Sleep Behavior ◽  
Preliminary Study
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