Trajectories in the Spinal Cord and the Mediolateral Spread in the Cerebellar Cortex of Spinocerebellar Fibers from the Unilateral Lumbosacral Enlargement in the Chicken

2011 ◽  
Vol 77 (1) ◽  
pp. 45-54 ◽  
Author(s):  
Masato Furue ◽  
Shinsuke Uchida ◽  
Aya Shinozaki ◽  
Tomohiro Imagawa ◽  
Yoshinao Z. Hosaka ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Cerebellar Cortex ◽  
Spinocerebellar Fibers

Reduction of CAG expansions in cerebellar cortex and spinal cord of DRPLA

2008 ◽  
Vol 50 (4) ◽  
pp. 199-201 ◽  
Author(s):  
M. Aoki ◽  
K. Abe ◽  
M. Tobita ◽  
T. Kameya ◽  
M. Watanabe ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Cerebellar Cortex

scholarly journals Partition of the Human Cerebellum in Sensory-Motor Activities, Learning and Cognition

1993 ◽  
Vol 20 (S3) ◽  
pp. S75-S77 ◽  
Author(s):  
P.E. Roland
Keyword(s):  
Spinal Cord ◽  
Cerebellar Cortex ◽  
Temporal Order ◽  
Motor Programs ◽  
Sensory Motor ◽  
Human Cerebellum ◽  
Motor Activities ◽  
Agonist And Antagonist ◽  
The Central Nervous System ◽  
Learning And Cognition

ABSTRACT:The circuitry of the cerebellum is quite well understood. The computation takes place in the cerebellar cortex, which functions in synchronized strips to provide excellent timing signals to the cerebral cortex and the spinal cord. The cerebellar cortex is also the site where error signals from other parts of the central nervous system are incorporated. For voluntary limb movements the cerebellular cortex is important for the timing of the innervation of the agonist and antagonist anterior horn neurons. It is also important for the temporal order of and precision in the execution of motor programs. As will be apparent, the cerebellum is not only a computer taking care of motor programs.

Inhibition of spinal cord dorsal horn neuronal activity by electrical stimulation of the cerebellar cortex

2011 ◽  
Vol 106 (5) ◽  
pp. 2515-2522 ◽  
Author(s):  
Christopher E. Hagains ◽  
Arun K. Senapati ◽  
Paula J. Huntington ◽  
Ji-Wei He ◽  
Yuan B. Peng
Keyword(s):  
Spinal Cord ◽  
Electrical Stimulation ◽  
Dorsal Horn ◽  
Cerebellar Cortex ◽  
Spinal Dorsal Horn ◽  
Dynamic Range ◽  
Spinal Cord Dorsal Horn ◽  
Spinal Dorsal ◽  
Spinal Cord Dorsal ◽  
Stimulation Of

The cerebellum plays a major role in not only modulating motor activity, but also contributing to other functions, including nociception. The intermediate hemisphere of the cerebellum receives sensory input from the limbs. With the extensive connection between the cerebellum to brain-stem structures and cerebral cortex, it is possible that the cerebellum may facilitate the descending system to modulate spinal dorsal horn activity. This study provided the first evidence to support this hypothesis. Thirty-one wide-dynamic-range neurons from the left lumbar and 27 from the right lumbar spinal dorsal horn were recorded in response to graded mechanical stimulation (brush, pressure, and pinch) at the hind paws. Electrical stimulation of the cerebellar cortex of the left intermediate hemisphere significantly reduced spinal cord dorsal horn neuron-evoked responses bilaterally in response to peripheral high-intensity mechanical stimuli. It is concluded that the cerebellum may play a potential antinociceptive role, probably through activating descending inhibitory pathways indirectly.

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