scholarly journals Osteopontin Overproduction Is Associated with Progression of Glomerular Fibrosis in a Rat Model of Anti-Glomerular Basement Membrane Glomerulonephritis

2010 ◽  
Vol 32 (3) ◽  
pp. 262-271 ◽  
Author(s):  
Justin Merszei ◽  
Jean Wu ◽  
Lisa Torres ◽  
John M. Hicks ◽  
Todd Bartkowiak ◽  
...  
Keyword(s):  
Basement Membrane ◽  
Rat Model ◽  
Glomerular Basement Membrane

Losartan preserves glomerular basement membrane anionic charge sites in a rat model of nephropathy

2012 ◽  
Vol 26 (4) ◽  
pp. 660-666 ◽  
Author(s):  
Yan Liu ◽  
Daoyuan Zhou ◽  
Xiao Xiao ◽  
Danping Qin ◽  
Xiaoshi Zhong ◽  
...  
Keyword(s):  
Basement Membrane ◽  
Rat Model ◽  
Glomerular Basement Membrane ◽  
Anionic Charge

Antiproteinuric effect of pirfenidone in a rat model of anti-glomerular basement membrane glomerulonephritis

2014 ◽  
Vol 737 ◽  
pp. 106-116 ◽  
Author(s):  
Koji Takakura ◽  
Kazuhiko Mizukami ◽  
Hikaru Mitori ◽  
Takahisa Noto ◽  
Yuichi Tomura
Keyword(s):  
Basement Membrane ◽  
Rat Model ◽  
Glomerular Basement Membrane ◽  
Antiproteinuric Effect

The effect of losartan and captopril on glomerular basement membrane anionic charge in a diabetic rat model

1999 ◽  
Vol 17 (8) ◽  
pp. 1217-1223 ◽  
Author(s):  
Dilek G. Yavuz ◽  
Önder Ersöz ◽  
Belgin Kuçükkaya ◽  
Yasemin Budak ◽  
Rengin Ahiskali ◽  
...  
Keyword(s):  
Basement Membrane ◽  
Rat Model ◽  
Glomerular Basement Membrane ◽  
Diabetic Rat ◽  
Anionic Charge ◽  
Diabetic Rat Model

Electron microscopic radioautographic studies on the incorporation of 3H proline in the glomerular basement membrane (GBM) in antistreptococcal-cell-membrane (SCM) injected mice

1984 ◽  
Vol 42 ◽  
pp. 188-189
Author(s):  
R.P. Nayyar ◽  
C.F. Lange ◽  
J. L. Borke
Keyword(s):  
Body Weight ◽  
Cell Membrane ◽  
Basement Membrane ◽  
Glomerular Basement Membrane ◽  
Mesangial Matrix ◽  
Electron Microscopic ◽  
Group A ◽  
Injection Protocol

Streptococcal cell membrane (SCM) antiserum injected mice show a significant thickening of glomerular basement membrane (GBM) and an increase in mesangial matrix within 4 to 24 hours of antiserum administration (1,2,3). This study was undertaken to evaluate the incorporation of 3H proline into glomerular cells and GBM under normal and anti-SCM induced conditions. Mice were administered, intraperitoneally, 0.1 ml of normal or anti-SCM serum followed by a 10 µC/g body weight injection of 3H proline. Details of the preparation of anti-SCM (Group A type 12 streptococcal pyogenes) and other sera and injection protocol have been described elsewhere (2). After 15 minutes of isotope injection a chase of cold proline was given and animal sacrificed at 20 minutes, 1,2,4,8,24 and 48 hours. One of the removed kidneys was processed for immunofluorescence, light and electron microscopic radioautographic studies; second kidney was used for GBM isolation and aminoacid analysis.

Fibronectin binding to glomerular basement membrane is altered in diabetes

Diabetes ◽  
1987 ◽  
Vol 36 (6) ◽  
pp. 758-763 ◽  
Author(s):  
M. P. Cohen ◽  
R. Saini ◽  
H. Klepser ◽  
L. G. Vasanthi
Keyword(s):  
Basement Membrane ◽  
Glomerular Basement Membrane ◽  
Fibronectin Binding
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