Heart Failure: Pathophysiology and Clinical Picture

Author(s):  
Alberto Palazzuoli ◽  
Ranuccio Nuti

The article presents a clinical case of advanced malignant lymphoma of the anterior mediastinum with the development of total heart failure. In most cases, this type of tumors are detected at the last stage, in the absence of a clinical picture at an earlier stage. Thus, the guarantee of timely provision of medical care is on time medical examinations with the performance of radiographic examinations of the chest organs.


Author(s):  
Kengo Kusano ◽  
Kohei Ishibashi ◽  
Kosuke Nakasuka ◽  
Yoichi Takaya ◽  
Toshiyuki Nagai ◽  
...  

2017 ◽  
Vol 10 (3) ◽  
pp. 1138-1143
Author(s):  
Martin Ignacio Zapata Laguado ◽  
Jonathan Orlando Palacios Rojas ◽  
Efraín Alonso Gómez Lopez ◽  
Martha Lucía Velasco Morales ◽  
Carlos Eduardo Orozco de la Hoz

Primary pleomorphic sarcoma of the left atrium is a rare tumor. There is no actual evidence of the management of this pathological entity, so the main treatment is individualized, surgical management being the cornerstone of the treatment. We present a 78-year-old female who had a clinical picture of heart failure, documenting an atrial mass of the left atrium, with high-grade pleomorphic sarcoma revealed in histopathology. The tumor was surgical removed, with no clinical evidence of residual mass. The tumor recurred again within 3 years, to which the patient succumbed.


2015 ◽  
Vol 2 (2) ◽  
pp. 47-48
Author(s):  
Abdelilah Ghannam ◽  
Zakaria Ouassou ◽  
Jawad Tadili ◽  
Ali Kettani ◽  
Mamoun Faroudy

Cardiothyreosis is a rare and serious complication of thyroid disease. We report a case that is unique in its inaugural clinical picture (status epilepticus) due to late diagnosis and iatrogenic drug which precipitated the patient in an array of congestive heart failure where therapeutic management was limited by insufficient technical facilities leading to death.


2013 ◽  
Vol 4 (3) ◽  
pp. 56-60
Author(s):  
E L Soyustova

It is considered the case of severe heart failure in patient with Graves' Disease. Its special feature is the dominance of circulatory decompensation events in clinical picture.


F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 1006
Author(s):  
Attila Frigy ◽  
Zoltán Fogarasi ◽  
Ildikó Kocsis ◽  
Lehel Máthé ◽  
Előd Nagy

Abstract In a cohort of patients hospitalized with acute heart failure (AHF) the prevalence of anemia and the existence of a correlation between anemia and the severity of the clinical picture were assessed. Methods. 50 consecutive patients (34 men, 16 women, mean age 67.5 years) hospitalized with AHF were enrolled.  Statistical analysis was performed using a chi-square test, for studying univariate correlation between anemia and the presence of diverse parameters reflecting the severity and prognosis of AHF (α=0.05). Results. 21 patients (14 men, 7 women, mean age 69.6 years), representing 42%, had anemia (Hb<12 g/dl) at admission. Comparing patients with and without anemia there were no significant differences regarding age,  gender,  presence of atrial fibrillation (p=0.75), diabetes (p=1), ischemic heart disease (p=0.9), ejection fraction < 35% (p=1), hypotension at admission (p=0.34), tachycardia>100 b/min at admission (p=0.75), creatinine level >1.5mg% (p=0.12), and need of high dose of loop diuretic >80 mg/day (p=0.23). Conclusions. Anemia is a frequent finding in patients hospitalized with AHF. The presence of anemia was not correlated with other factors related to AHF severity and prognosis. This fact suggests its independent role in influencing the clinical picture and prognosis.


2020 ◽  
Vol 25 (1) ◽  
pp. 26-32
Author(s):  
O. G. Goryacheva ◽  
A. N. Koziolova

Aim. To determine the features of heart failure (HF) development in patients with human immunodeficiency virus (HIV) infection.Material and methods. In a general hospital, 160 patients were examined during the year. All of them were divided into 2 groups: group 1 (n=100) — HIV-infected patients with specific clinical picture of HF; group 2 (n=60) — patients without HIV infection and with HF verified by echocardiography and concentration of N-terminal prohormone of brain natriuretic peptide (NT-proBNP).Results. In comparison with group 2, HIV-infected patients had the following statistically significant differences: lower left ventricular ejection fraction (LVEF), lower prevalence and severity of left ventricle diastolic dysfunction, higher LV mass index (LVMI), and lower NT-proBNP. HIV-infected patients had statistically significant moderate inverse relationship of LVEF (r=-0,43; p=0,015), E/e’ (r=-0,32; p=0,045), LVMI (r=-0,46; p=0,002) and strong relationship of NT-proBNP (r=-0,54; p<0,001) with CD4 T-lymphocyte count in 1 mm3 in the presence of HF symptoms and signs and an increase in NT-proBNP over 125 pg/ml. In group 1, there was a significantly higher prevalence of smoking, chronic alcoholism, drug use, chronic hepatitis C and cirrhosis (especially manifested by hepatomegaly and splenomegaly in combination with ascites and hepatic cytolysis), chronic pancreatitis, pneumonia and inflammatory diseases accompanied by higher erythrocyte sedimentation rate and C-reactive protein concentration, and lower hemoglobin level. HIV-infected patients were statistically less likely to use all groups of drugs for HF treatment, with the exception of spironolactone, and more likely to use drugs for multimorbidity treatment.Conclusion. The HF prevalence in hospitalized HIV-infected patients, estimated on the basis of symptoms and NT-proBNP increase >125 pg/ml, was 54%; on the basis of LVEF decrease <50% — 32%. The clinical picture of HIV-infected patients is characterized by various symptoms, including those typical for HF with normal NT-proBNP level, due to the high prevalence of comorbidities and concurrent medication.


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