scholarly journals ATYPICAL CLINICAL FEATURES OF HYPERTHYROIDISM. CASE STUDY

2013 ◽  
Vol 4 (3) ◽  
pp. 56-60
Author(s):  
E L Soyustova
Keyword(s):  
Heart Failure ◽  
Clinical Features ◽  
Clinical Picture ◽  
Severe Heart Failure ◽  
Graves Disease

It is considered the case of severe heart failure in patient with Graves' Disease. Its special feature is the dominance of circulatory decompensation events in clinical picture.

scholarly journals Pseudo-Myasthenia Gravis and Thymic Hyperplasia in Graves’ Disease

1999 ◽  
Vol 26 (3) ◽  
pp. 201-203 ◽  
Author(s):  
Michael W. Nicolle
Keyword(s):  
Myasthenia Gravis ◽  
Clinical Features ◽  
Mediastinal Mass ◽  
Lymphoid Hyperplasia ◽  
Thymic Hyperplasia ◽  
Graves Disease ◽  
Grave’S Disease ◽  
Diagnostic Confusion ◽  
Grave's Disease

Background:Diagnostic confusion between thyroid disease and myasthenia gravis (MG) can arise because the two may have similar clinical features, and also because of the more frequent coexistence of these autoimmune disorders in the same individual. In MG, autoantibodies directed against the acetylcholine receptor result in muscle weakness. Thymic pathology is well recognized in MG, with thymic hyperplasia frequent in early onset MG and thymoma more common in later onset MG. In Graves’ disease, autoantibodies against thyroid antigens result in hyperthyroidism. A seldom-recognized feature of Grave’s disease is the occurrence of an enlarged thymus (thymic hyperplasia) on chest CT, or of thymic lymphoid hyperplasia pathologically.Case study:This report describes a case in which the discovery of a mediastinal mass during imaging of the thyroid, and the presence of myasthenic-like symptoms, in a patient with Graves’ disease prompted investigations into whether the patient also had MG.Results:Despite symptoms which strongly suggested MG, subsequent investigations did not confirm the diagnosis, and treatment of Grave’s lead to a resolution of the symptoms and regression of the thymic enlargement seen on CT.Conclusion:The case study highlighted clinical similarities between Grave’s disease and myasthenia gravis which might cause diagnostic confusion, and also the investigations which are useful in order to differentiate the two diseases. In addition to common clinical features, the autoimmune diseases Grave’s disease and myasthenia gravis may both produce radiological thymic enlargement.

scholarly journals Clinical features of Neonatal Cardiomyopathy

2019 ◽  
Vol 2 (3) ◽  
pp. 115-119
Author(s):  
Sakurai K ◽  
Nakano M ◽  
Masumori C ◽  
Mizuno M ◽  
Aso K
Keyword(s):  
Heart Failure ◽  
Heart Transplantation ◽  
Clinical Features ◽  
Noonan Syndrome ◽  
Severe Heart Failure ◽  
Left Ventricular ◽  
Leopard Syndrome ◽  
Cardiac Murmur ◽  
Underlying Diseases

Background: Neonatal cardiomyopathy is a rare disease that ranges from being asymptomatic to abruptly lethal and is not well characterized [1]. We investigated the clinical features of five neonates with cardiomyopathy in our hospital to determine key clinical characteristics. Methods: We retrospectively reviewed the records of five newborns who were diagnosed with cardiomyopathy between January 2000 and December 2018. The primary evaluation included reasons for diagnosis, underlying diseases, therapy, and turning point. Results: Patients with hypertrophic cardiomyopathy (HCM) or left ventricular noncompaction (LVNC) were diagnosed on the basis of cardiac murmur, while the patient with dilated cardiomyopathy (DCM) was diagnosed on the basis of sucking failure. Underlying diseases included Noonan syndrome and LEOPARD syndrome. All patients had received β-blockers, and those with DCM and LVNC were also administered diuretics and angiotensin-converting enzyme inhibitors. The two patients with HCM underwent follow-up as out-patients. One patient with HCM died at 3 years old because of arrhythmia. The patient with DCM died due to heart failure 38 days after birth. The patient with LVNC exhibited severe heart failure after birth, requiring follow-up while considering heart transplantation. Conclusion: Noonan syndrome and LEOPARD syndrome, which is RAS/MAPK-related diseases, should be considered in patients diagnosed HCM. Because heart failure progresses rapidly in patients with neonatal DCM and those with LVNC, planned therapy should include consideration of heart transplantation.

523 Troponin I could stratify the patients with severe heart failure

2003 ◽  
Vol 2 (1) ◽  
pp. 108
Author(s):  
G DAN ◽  
A DAN ◽  
I DAHA ◽  
C STANESCU ◽  
V ILIE ◽  
...  
Keyword(s):  
Heart Failure ◽  
Troponin I ◽  
Severe Heart Failure
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