Impaired Growth Hormone Receptor Signaling during Non-Catch-Up Growth in Rats Born Small for Gestational Age

2010 ◽  
Vol 74 (2) ◽  
pp. 106-113 ◽  
Author(s):  
Yuefang Huang ◽  
Minlian Du ◽  
Siqi Zhuang ◽  
Zhenyu Shen ◽  
Yijuan Li
Keyword(s):  
Growth Hormone ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Hormone Receptor ◽  
Growth Hormone Receptor ◽  
Receptor Signaling ◽  
Catch Up

Laron syndrome – A case Report

JMS SKIMS ◽  
2017 ◽  
Vol 20 (2) ◽  
pp. 104-106
Author(s):  
Javaid Ahmad Bhat ◽  
Moomin Hussain Bhat ◽  
Hilal Bhat ◽  
Mona Sood ◽  
Shariq Rashid Masoodi
Keyword(s):  
Growth Hormone ◽  
Case Report ◽  
Hormone Receptor ◽  
Growth Hormone Receptor ◽  
Genetic Disorder ◽  
Female Child ◽  
Receptor Signaling ◽  
Laron Syndrome ◽  
Rare Genetic Disorder ◽  
Igf I

Background : Laron & colleagues (1966) reported a rare genetic disorder in Israliei Jewish sublings which was characterized by insensitivity to growth hormone due to abnormality in growth hormone receptor or post receptor signaling pathway.Case Report: We hereby report a case of a 5 year old female child who presented to us with features similar to Laron syndrome. The diagnosis was made & confirmed by various Lab. investigations like low IGF-I levels and managed accordingly. JMS 2017; 20 (2):104-106  

scholarly journals Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice

2010 ◽  
Vol 120 (11) ◽  
pp. 4007-4020 ◽  
Author(s):  
Mahendra D. Mavalli ◽  
Douglas J. DiGirolamo ◽  
Yong Fan ◽  
Ryan C. Riddle ◽  
Kenneth S. Campbell ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Growth Hormone ◽  
Insulin Sensitivity ◽  
Hormone Receptor ◽  
Growth Hormone Receptor ◽  
Muscle Development ◽  
Receptor Signaling ◽  
Skeletal Muscle Development

scholarly journals Protein-tyrosine Phosphatase H1 Controls Growth Hormone Receptor Signaling and Systemic Growth

2007 ◽  
Vol 282 (48) ◽  
pp. 35405-35415 ◽  
Author(s):  
Iwona Pilecka ◽  
Claudia Patrignani ◽  
Rosanna Pescini ◽  
Marie-Laure Curchod ◽  
Dominique Perrin ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Protein Tyrosine Phosphatase ◽  
Hormone Receptor ◽  
Growth Hormone Receptor ◽  
Tyrosine Phosphatase ◽  
Receptor Signaling ◽  
Protein Tyrosine

Growth Hormone Treatment Induces a Dose-Dependent Catch-Up Growth in Short Children Born Small for Gestational Age: A Summary of Four Clinical Trials

1997 ◽  
Vol 48 (1) ◽  
pp. 67-71 ◽  
Author(s):  
Patrick Wilton ◽  
Kerstin Albertsson-Wikland ◽  
Otfrid Butenandt ◽  
Jean-Louis Chaussain ◽  
Francis de Zegher ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Clinical Trials ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Short Children ◽  
Catch Up ◽  
Dose Dependent

scholarly journals Growth hormone receptor signaling is dispensable for HSC function and aging

Blood ◽  
2014 ◽  
Vol 124 (20) ◽  
pp. 3076-3080 ◽  
Author(s):  
Morag H. Stewart ◽  
Paula Gutierrez-Martinez ◽  
Isabel Beerman ◽  
Brian Garrison ◽  
Emily J. Gallagher ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Hormone Receptor ◽  
Growth Hormone Receptor ◽  
Receptor Signaling ◽  
Hematopoietic System ◽  
Key Points

Key Points Ghr is specifically expressed on HSCs within the hematopoietic system and is dynamically regulated upon HSC aging and activation. Ghr is dispensable for HSC function.

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