Retinol-Binding Protein 4 Levels in Obese Children and Adolescents with Glucose Intolerance

2010 ◽  
Vol 73 (5) ◽  
pp. 335-340 ◽  
Author(s):  
D. Yeste ◽  
J. Vendrell ◽  
R. Tomasini ◽  
L.L. Gallart ◽  
M. Clemente ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Glucose Intolerance ◽  
Binding Protein ◽  
Retinol Binding Protein ◽  
Obese Children ◽  
Retinol Binding Protein 4

Retinol-Binding Protein 4 Levels Are Associated with Measures of Liver and Renal Function and Oxidant/Antioxidant Status in Obese Children

2013 ◽  
Vol 163 (2) ◽  
pp. 593-595 ◽  
Author(s):  
Pilar Codoñer-Franch ◽  
Antonio Mora-Herranz ◽  
Raquel Simó-Jordá ◽  
Clara Pérez-Rambla ◽  
Laura Boix-García ◽  
...  
Keyword(s):  
Renal Function ◽  
Antioxidant Status ◽  
Binding Protein ◽  
Retinol Binding Protein ◽  
Obese Children ◽  
Retinol Binding Protein 4

ALTERED CIRCULATING LEVELS OF RETINOL BINDING PROTEIN 4 AND TRANSTHYRETIN IN RELATION TO INSULIN RESISTANCE, OBESITY, AND GLUCOSE INTOLERANCE IN ASIAN INDIANS

2015 ◽  
Vol 21 (8) ◽  
pp. 861-869 ◽  
Author(s):  
Gautam Kumar Pandey ◽  
Jayashree Balasubramanyam ◽  
Mahalingam Balakumar ◽  
Mohan Deepa ◽  
Ranjit Mohan Anjana ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Glucose Intolerance ◽  
Asian Indians ◽  
Binding Protein ◽  
Retinol Binding Protein ◽  
Retinol Binding Protein 4 ◽  
Circulating Levels

scholarly journals Plasma retinol-binding protein 4 in the first and second trimester and risk of gestational diabetes mellitus in Chinese women: a nested case-control study

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Chuyao Jin ◽  
Lizi Lin ◽  
Na Han ◽  
Zhiling Zhao ◽  
Zheng Liu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Binding Protein ◽  
First Trimester ◽  
Retinol Binding Protein ◽  
Second Trimester ◽  
Retinol Binding Protein 4 ◽  
Plasma Retinol

Abstract Background To assess the association between plasma retinol-binding protein 4 (RBP4) levels both in the first trimester and second trimester and risk of gestational diabetes mellitus (GDM). Methods Plasma RBP4 levels and insulin were measured among 135 GDM cases and 135 controls nested within the Peking University Birth Cohort in Tongzhou. Multivariable linear regression analysis was conducted to assess the influence of RBP4 levels on insulin resistance. Conditional logistic regression models were used to compute the odds ratio (OR) and 95% confidence interval (CI) between RBP4 levels and risk of GDM. Results The GDM cases had significantly higher levels of RBP4 in the first trimester than controls (medians: 18.0 μg/L vs 14.4 μg/L; P < 0.05). Plasma RBP4 concentrations in the first and second trimester were associated with fasting insulin, homeostasis model assessment for insulin resistance (HOMA-IR), and the quantitative insulin sensitivity check index (QUICKI) in the second trimester (all P < 0.001). With adjustment for diet, physical activity, and other risk factors for GDM, the risk of GDM increased with every 1-log μg/L increment of RBP4 levels, and the OR (95% CI) was 3.12 (1.08–9.04) for RBP4 in the first trimester and 3.38 (1.03–11.08) for RBP4 in the second trimester. Conclusions Plasma RBP4 levels both in the first trimester and second trimester were dose-dependently associated with increased risk of GDM.

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