The Induction of the Shwartzman Phenomenon in the Rabbit Cornea

1956 ◽  
Vol 132 (3) ◽  
pp. 137-140 ◽  
Author(s):  
R. Raus
Keyword(s):  
Rabbit Cornea ◽  
Shwartzman Phenomenon

The Local Sanarelli-Shwartzman Phenomenon in Rats Induced by Human Leukaemic Cells

1973 ◽  
Vol 29 (02) ◽  
pp. 353-362
Author(s):  
J Lisiewicz ◽  
A Pituch ◽  
J. A Litwin
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Intravenous Injection ◽  
Peripheral Blood ◽  
Lymphocytic Leukaemia ◽  
Acute Myeloblastic Leukaemia ◽  
Demarcation Line ◽  
E Coli ◽  
Leukaemic Cells ◽  
Shwartzman Phenomenon

SummaryThe local Sanarelli-Shwartzman phenomenon (SSP-L) in the skin of 30 rats was induced by an intr a cutaneous sensitizing injection of leukaemic leucocytes isolated from the peripheral blood of patients with chronic lymphocytic leukaemia (CLL), acute myeloblastic leukaemia (AL) and chronic granulocytic leukaemia (CGL) and challenged by an intravenous injection of 100(μ of E. coli endotoxin. SSP-L was observed in 7 rats after injection of CLL lymphocytes and in 6 and 2 rats after AL myeloblasts and the CGL granulocytes, respectively. The lesions in the skin after AL myeloblasts appeared in a shorter time and were of longer duration compared with those observed after CLL lymphocytes and CGL granulocytes. Histologically, the lesions consisted of areas of destruction in the superficial layers of the skin ; the demarcation line showed the presence of neutrophils, macrophages and erythrocytes. Haemorrhages and fibrin deposits near the demarcation line were larger after injection of CLL lymphocytes and AL myeloblasts than after CGL granulocytes. The possible role of leucocyte procoagulative substances in the differences observed have been discussed.

A Re-Appraisal of the Role of Blood Coagulation and Platelets in the Generalized Shwartzman Phenomenon

1966 ◽  
Vol 15 (03/04) ◽  
pp. 519-538 ◽  
Author(s):  
J Levin ◽  
E Beck
Keyword(s):  
Blood Coagulation ◽  
The State ◽  
Coagulation System ◽  
Renal Lesions ◽  
Intravascular Coagulation ◽  
Renal Glomeruli ◽  
Coagulation Mechanism ◽  
Shwartzman Phenomenon ◽  
Do So

SummaryThe role of intravascular coagulation in the production of the generalized Shwartzman phenomenon has been evaluated. The administration of endotoxin to animals prepared with Thorotrast results in activation of the coagulation mechanism with the resultant deposition of fibrinoid material in the renal glomeruli. Anticoagulation prevents alterations in the state of the coagulation system and inhibits development of the renal lesions. Platelets are not primarily involved. Platelet antiserum produces similar lesions in animals prepared with Thorotrast, but appears to do so in a manner which does not significantly involve intravascular coagulation.The production of adrenal cortical hemorrhage, comparable to that seen in the Waterhouse-Friderichsen syndrome, following the administration of endotoxin to animals that had previously received ACTH does not require intravascular coagulation and may not be a manifestation of the generalized Shwartzman phenomenon.

Local Anesthetic Action of Aqueous Extract of Citrullous Colocynthis Fruit on Rabbit Cornea

2012 ◽  
Vol 3 (4) ◽  
pp. 209-211
Author(s):  
Dr.T.Jayasree Dr.T.Jayasree ◽  
◽  
Dr Shaikh Ubedulla ◽  
Dr. Chandrasekhar Nutalapati ◽  
Naveen Aalasyam ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Local Anesthetic ◽  
Rabbit Cornea ◽  
Anesthetic Action

scholarly journals Biomechanical Measurement of Rabbit Cornea by a Modified Scheimpflug Device

2016 ◽  
Vol 2016 ◽  
pp. 1-6
Author(s):  
Bo Zhang ◽  
Jianjun Gu ◽  
Xiaoxiao Zhang ◽  
Bin Yang ◽  
Zheng Wang ◽  
...  
Keyword(s):  
Bulk Modulus ◽  
Correlation Coefficient ◽  
Intraclass Correlation Coefficient ◽  
Intraclass Correlation ◽  
Anterior Segment ◽  
Intraobserver Reliability ◽  
Rabbit Cornea ◽  
Deformation Response ◽  
Biomechanical Measurements ◽  
Biomechanical Measurement

Purpose. To explore the probability and variation in biomechanical measurements of rabbit cornea by a modified Scheimpflug device.Methods. A modified Scheimpflug device was developed by imaging anterior segment of the model imitating the intact eye at various posterior pressures. The eight isolated rabbit corneas were mounted on the Barron artificial chamber and images of the anterior segment were taken at posterior pressures of 15, 30, 45, 60, and 75 mmHg by the device. The repeatability and reliability of the parameters including CCT, ACD, ACV, and CV were evaluated at each posterior pressure. All the variations of the parameters at the different posterior pressures were calculated.Results. All parameters showed good intraobserver reliability (Cronbach’s alpha; intraclass correlation coefficient,α, ICC > 0.96) and repeatability in the modified Scheimpflug device. With the increase of posterior pressures, the ratio of CCT decreased linearly and the bulk modulus gradually reduced to a platform. The increase of ACD was almost linear with the posterior pressures elevated.Conclusions. The modified Scheimpflug device was a valuable tool to investigate the biomechanics of the cornea. The posterior pressure 15–75 mmHg range produced small viscoelastic deformations and nearly linear pressure-deformation response in the rabbit cornea.

scholarly journals Effects of ultraviolet laser beam irradiation on rabbit cornea and lens.

Sangyo Igaku ◽  
1988 ◽  
Vol 30 (2) ◽  
pp. 112-120 ◽  
Author(s):  
Sadafumi TAKISE ◽  
Shun'ichi HORIGUCHI ◽  
Ichiro KARAI ◽  
Shinya MATSUMURA ◽  
Makoto HARIMA ◽  
...  
Keyword(s):  
Laser Beam ◽  
Beam Irradiation ◽  
Rabbit Cornea ◽  
Ultraviolet Laser ◽  
Laser Beam Irradiation

Acute ocular effects of mustard gas: ultrastructural pathology and immunohistopathology of exposed rabbit cornea†

2001 ◽  
Vol 20 (S1) ◽  
pp. S173-S175 ◽  
Author(s):  
J. P. Petrali ◽  
E. J. Dick ◽  
J. J. Brozetti ◽  
T. A. Hamilton ◽  
A. V. Finger
Keyword(s):  
Mustard Gas ◽  
Rabbit Cornea ◽  
Ultrastructural Pathology

scholarly journals Analysis of glycosaminoglycans in rabbit cornea after excimer laser keratectomy

1999 ◽  
Vol 83 (5) ◽  
pp. 609-612 ◽  
Author(s):  
T. Kato ◽  
K. Nakayasu ◽  
K. Ikegami ◽  
T. Obara ◽  
T. Kanayama ◽  
...  
Keyword(s):  
Excimer Laser ◽  
Rabbit Cornea

The break-up time of artificial pre-ocular films on the rabbit cornea

1976 ◽  
Vol 28 (5) ◽  
pp. 450-451 ◽  
Author(s):  
J. W. Lamble ◽  
D. Gilbert ◽  
J. J. Ashford
Keyword(s):  
Rabbit Cornea ◽  
Break Up
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