Characterization of the Nuclear Progesterone Receptor in Normal Human Endometrium after Progesterone Injection

1987 ◽  
Vol 23 (1) ◽  
pp. 48-53
Author(s):  
I.G. Gorodeski ◽  
C.M. Bahary ◽  
R. Beery ◽  
B. Lunenfeld ◽  
A. Geier
2021 ◽  
Vol 8 ◽  
Author(s):  
Ahmed M. Nagy ◽  
Swanand R. Sathe ◽  
Attia H. Atta ◽  
Abdel Mohsen M. Hammam ◽  
Walter H. Hsu

In equine parturition, the role of progestins along with the nuclear progesterone receptor (nPR) signaling pathway in the placenta is not completely clarified. The progestins play an integral role in maintaining myometrial quiescence during the late stage of pregnancy via acting on nPR isoforms (PRA and PRB; PRB is more active than PRA). The current study aimed to determine the PRA and PRB expressions in the term equine placenta at the gene and protein levels. Six term equine placentas were used in this study. Reverse transcription polymerase chain reaction (RT-PCR) was used to quantify the mRNA expression for PRA and PRB. The protein expression was detected using the Western Blot technique. The results revealed that the mRNA and protein expressions for PRA were significantly higher (P < 0.0001) in the term equine placental tissue compared to the mRNA and protein expressions of PRB. These results demonstrated that nPRs are detectable in the term placenta of mares and PRA is the dominant isoform expressed. The present findings raised the possibility that the PRA plays an important role in the parturition process and expulsion of the placenta in mares.


Author(s):  
Israel G. Gorodeski ◽  
Avraham Geier ◽  
Rachel Beery ◽  
Charles M. Bahary ◽  
Alexander Neri ◽  
...  

Maturitas ◽  
1986 ◽  
Vol 8 (4) ◽  
pp. 345-352 ◽  
Author(s):  
I.G. Gorodeski ◽  
A. Geier ◽  
R. Beery ◽  
B. Lunenfeld ◽  
D. Serr ◽  
...  

Endocrinology ◽  
1988 ◽  
Vol 123 (5) ◽  
pp. 2506-2513 ◽  
Author(s):  
PETER D. FEIL ◽  
CHRISTINE L. CLARKE ◽  
PONDICHERY G. SATYASWAROOP

In Vitro ◽  
1984 ◽  
Vol 20 (6) ◽  
pp. 451-462 ◽  
Author(s):  
G. M. Centola ◽  
M. Cisar ◽  
D. R. Knab

Sign in / Sign up

Export Citation Format

Share Document