scholarly journals Antibiotic Concentration in Maternal Blood, Cord Blood and Placental Tissue in Women with Chorioamnionitis

1992 ◽  
Vol 33 (3) ◽  
pp. 185-186 ◽  
Author(s):  
Mark C. Maberry ◽  
Kenneth J. Trimmer ◽  
Roger E. Bawdon ◽  
Sorab Sobhi ◽  
Jody B. Dax ◽  
...  
Keyword(s):  
Cord Blood ◽  
Placental Tissue ◽  
Maternal Blood ◽  
Antibiotic Concentration

Associations between maternal prenatal stress, methylation changes in IGF1 and IGF2, and birth weight

2017 ◽  
Vol 9 (2) ◽  
pp. 215-222 ◽  
Author(s):  
D. Montoya-Williams ◽  
J. Quinlan ◽  
C. Clukay ◽  
N. C. Rodney ◽  
D. A. Kertes ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Cord Blood ◽  
Prenatal Stress ◽  
Maternal Stress ◽  
Democratic Republic Of Congo ◽  
Placental Tissue ◽  
Maternal Blood ◽  
Tissue Samples

Maternal stress has been linked to low birth weight in newborns. One potential pathway involves epigenetic changes at candidate genes that may mediate the effects of prenatal maternal stress on birth weight. This relationship has been documented in stress-related genes, such as NR3C1. There is less literature exploring the effect of stress on growth-related genes. IGF1 and IGF2 have been implicated in fetal growth and development, though via different mechanisms as IGF2 is under imprinting control. In this study, we tested for associations between prenatal stress, methylation of IGF1 and IGF2, and birth weight. A total of 24 mother–newborn dyads in the Democratic Republic of Congo were enrolled. Ethnographic interviews were conducted with mothers at delivery to gather culturally relevant war-related and chronic stressors. DNA methylation data were generated from maternal venous, cord blood and placental tissue samples. Multivariate regressions were used to test for associations between stress measures, DNA methylation and birth weight in each of the three tissue types. We found an association between IGF2 methylation in maternal blood and birth weight. Previous literature on the relationship between IGF2 methylation and birth weight has focused on methylation at known differentially methylated regions in cord blood or placental samples. Our findings indicate there may be links between the maternal epigenome and low birth weight that rely on mechanisms outside known imprinting pathways. It thus may be important to consider the effect of maternal exposures and epigenetic profiles on birth weight even in the setting of maternally imprinted genes such as IGF2.

Is there a relationship between metallothionein polymorphism and mercury levels of maternal blood, placental tissue and cord blood?

2016 ◽  
Vol 258 ◽  
pp. S290
Author(s):  
Z. Kayaaltı ◽  
D. Kaya Akyüzlü ◽  
B. Yüksel ◽  
F. Özdemir ◽  
T. Söylemezoğlu
Keyword(s):  
Cord Blood ◽  
Placental Tissue ◽  
Maternal Blood

Low maternal B12 associates with higher leptin in maternal adipose tissue, placental tissue and cord blood

2016 ◽  
Author(s):  
Antonysunil Adaikalakoteswari ◽  
Manu Vatish ◽  
Ilona Goljan ◽  
Ponnusamy Saravanan
Keyword(s):  
Adipose Tissue ◽  
Cord Blood ◽  
Placental Tissue

Florid Bacillus cereus Infection of the Placenta Associated With Intrauterine Fetal Demise

2021 ◽  
pp. 109352662199902
Author(s):  
Stephanie Shea ◽  
Alberto Paniz-Mondolfi ◽  
Emilia Sordillo ◽  
Michael Nowak ◽  
Fumiko Dekio
Keyword(s):  
Bacillus Cereus ◽  
Placental Tissue ◽  
Maternal Blood ◽  
Gastrointestinal Infections ◽  
Gram Positive ◽  
Fetal Demise ◽  
Placental Infection ◽  
Intrauterine Fetal Demise ◽  
Acute Necrotizing ◽  
Poor Outcomes

Bacillus cereus is a gram-positive, rod-shaped bacterium that is commonly implicated in foodborne illness but has also become increasingly recognized as a source of serious non-gastrointestinal infections, including sepsis, meningitis, and pneumonia. Non-gastrointestinal B. cereus infections have been identified in children, especially in neonates; however, there are no previously described cases of fetal demise associated with B. cereus placental infection. We present a case of acute chorioamnionitis-related intrauterine fetal demise of twin A at 17 weeks gestation, noted two days after selective termination of twin B. Histological examination revealed numerous gram-positive bacilli in placental tissue, as well as fetal vasculature, in the setting of severe acute necrotizing chorioamnionitis and subchorionitis, intervillous abscesses, acute villitis, and peripheral acute funisitis. Cultures of maternal blood and placental tissue both yielded growth of B. cereus. This case underscores the importance of B. cereus as a human pathogen, and specifically demonstrates its potential as an agent of severe intraamniotic and placental infection with poor outcomes for the fetus.

scholarly journals Effect of Maternal Nutritional Status and Mode of Delivery on Zinc and Iron Stores at Birth

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 860
Author(s):  
Oraporn Dumrongwongsiri ◽  
Pattanee Winichagoon ◽  
Nalinee Chongviriyaphan ◽  
Umaporn Suthutvoravut ◽  
Veit Grote ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Cord Blood ◽  
Mode Of Delivery ◽  
Serum Zinc ◽  
Maternal Blood ◽  
Second Trimester ◽  
Food Frequency ◽  
Iron Stores ◽  
Maternal Nutritional Status ◽  
Blood Zinc

Zinc and iron deficiencies among infants aged under 6 months may be related with nutrient store at birth. This study aimed to investigate the association between zinc and iron stores at birth with maternal nutritional status and intakes during pregnancy. 117 pregnant women were enrolled at the end of second trimester and followed until delivery. Clinical data during pregnancy, including pre-pregnancy body mass index (BMI) and at parturition were collected from medical record. Zinc and iron intakes were estimated from a food frequency questionnaire. Serum zinc and ferritin were determined in maternal blood at enrollment and cord blood. Mean cord blood zinc and ferritin were 10.8 ± 2.6 µmol/L and 176 ± 75.6 µg/L, respectively. Cord blood zinc was associated with pre-pregnancy BMI (adj. ß 0.150; p = 0.023) and serum zinc (adj. ß 0.115; p = 0.023). Cord blood ferritin was associated with pre-pregnancy BMI (adj. ß −5.231; p = 0.009). Cord blood zinc and ferritin were significantly higher among those having vaginal delivery compared to cesarean delivery (adj. ß 1.376; p = 0.007 and 32.959; p = 0.028, respectively). Maternal nutritional status and mode of delivery were significantly associated with zinc and iron stores at birth. Nutrition during preconception and pregnancy should be ensured to build adequate stores of nutrients for infants.

Growth Hormone and Insulin-Like Growth Factor I Levels in Maternal Blood and the Cord Blood of Full-Term Infants

1989 ◽  
Vol 78 (s349) ◽  
pp. 145-145
Author(s):  
S. HATEMI ◽  
H.H. HATEMI ◽  
C. GULBABA ◽  
T. GULBABA ◽  
H. BOZKURT ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Factor ◽  
Cord Blood ◽  
Maternal Blood ◽  
Full Term ◽  
Insulin Like Growth Factor ◽  
Term Infants ◽  
Factor I ◽  
Growth Factor I
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