Tioconazole, a New Broad-Spectrum Antifungal Agent: Preclinical Studies Related to Vaginal Candidiasis

1983 ◽  
Vol 23 (1) ◽  
pp. 1-11
Author(s):  
M.S. Marriott ◽  
K.W. Brammer ◽  
J. Faccini ◽  
J.K. Faulkner ◽  
S. Jevons ◽  
...  
Keyword(s):  
Broad Spectrum ◽  
Antifungal Agent ◽  
Vaginal Candidiasis ◽  
Preclinical Studies

Highly stereoselective access to novel 2,2,4-substituted tetrahydrofurans by halocyclization: Practical chemoenzymatic synthesis of Sch 51048, a broad-spectrum orally active antifungal agent

1995 ◽  
Vol 36 (11) ◽  
pp. 1787-1790 ◽  
Author(s):  
Anil K Saksena ◽  
Viyyoor M Girijavallabhan ◽  
Raymond G Lovey ◽  
Russell E Pike ◽  
Haiyan Wang ◽  
...  
Keyword(s):  
Broad Spectrum ◽  
Antifungal Agent ◽  
Chemoenzymatic Synthesis ◽  
Orally Active

scholarly journals Isavuconazole: A New Broad-Spectrum Triazole Antifungal Agent

2015 ◽  
Vol 61 (10) ◽  
pp. 1558-1565 ◽  
Author(s):  
Marisa H. Miceli ◽  
Carol A. Kauffman
Keyword(s):  
Broad Spectrum ◽  
Antifungal Agent

Improved Laboratory Synthesis of YC-071, a Potent Azole Antifungal Agent

2017 ◽  
Vol 41 (4) ◽  
pp. 241-245 ◽  
Author(s):  
Yazhou Zheng ◽  
Anran Qian ◽  
Chenyu Ling ◽  
Xufeng Cao ◽  
YongMei Cui ◽  
...  
Keyword(s):  
Antifungal Agent ◽  
Preclinical Studies ◽  
Scalable Synthesis ◽  
Laboratory Synthesis

An improved laboratory synthesis of YC-071, a potent azole antifungal agent, has been developed. Compared with the original route, the new route is operationally simple, requiring only limited purification of all the intermediates. The new route is an important scalable synthesis, which meets the need for YC-071 for use in preclinical studies.

scholarly journals Posaconazole: A Broad-Spectrum Triazole Antifungal Agent

2007 ◽  
Vol 45 (12) ◽  
pp. 1610-1617 ◽  
Author(s):  
V. Nagappan ◽  
S. Deresinski
Keyword(s):  
Broad Spectrum ◽  
Antifungal Agent
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