scholarly journals Temporal Phase Relation of Circadian Neural Oscillations Alters RFamide-Related Peptide-3 and Testicular Function in the Mouse

2010 ◽  
Vol 91 (2) ◽  
pp. 189-199 ◽  
Author(s):  
Sumit Sethi ◽  
Kazuyoshi Tsutsui ◽  
Chandra Mohini Chaturvedi
Keyword(s):  
Phase Relation ◽  
Neural Oscillations ◽  
Testicular Function ◽  
Related Peptide ◽  
Temporal Phase

scholarly journals Both ongoing alpha and visually induced gamma oscillations show reliable diversity in their across-site phase-relations

2015 ◽  
Vol 113 (5) ◽  
pp. 1556-1563 ◽  
Author(s):  
Freek van Ede ◽  
Stan van Pelt ◽  
Pascal Fries ◽  
Eric Maris
Keyword(s):  
Phase Relation ◽  
Visual Stimulation ◽  
Low Frequency ◽  
Gamma Oscillations ◽  
Phase Relations ◽  
Neural Oscillations ◽  
High Signal ◽  
Noninvasive Methods ◽  
Healthy Human ◽  
Systems Neuroscience

Neural oscillations have emerged as one of the major electrophysiological phenomena investigated in cognitive and systems neuroscience. These oscillations are typically studied with regard to their amplitude, phase, and/or phase coupling. Here we demonstrate the existence of another property that is intrinsic to neural oscillations but has hitherto remained largely unexplored in cognitive and systems neuroscience. This pertains to the notion that these oscillations show reliable diversity in their phase-relations between neighboring recording sites (phase-relation diversity). In contrast to most previous work, we demonstrate that this diversity is restricted neither to low-frequency oscillations nor to periods outside of sensory stimulation. On the basis of magnetoencephalographic (MEG) recordings in humans, we show that this diversity is prominent not only for ongoing alpha oscillations (8–12 Hz) but also for gamma oscillations (50–70 Hz) that are induced by sustained visual stimulation. We further show that this diversity provides a dimension within electrophysiological data that, provided a sufficiently high signal-to-noise ratio, does not covary with changes in amplitude. These observations place phase-relation diversity on the map as a prominent and general property of neural oscillations that, moreover, can be studied with noninvasive methods in healthy human volunteers. This opens important new avenues for investigating how neural oscillations contribute to the neural implementation of cognition and behavior.

scholarly journals Serotonergic and catecholaminergic (dopaminergic) oscillations in the reproductive regulation of Japanese quail

2018 ◽  
Author(s):  
Suneeta Yadav ◽  
Chandra Mohini Chaturvedi
Keyword(s):  
Phase Relation ◽  
Time Interval ◽  
Specific Time ◽  
Serotonin Synthesis ◽  
Reproductive Regulation ◽  
Dopaminergic Drug ◽  
Temporal Phase ◽  
Gonadal Activity ◽  
Active Condition ◽  
Specific Phase

AbstractSpecific temporal phase relation of serotonergic and dopaminergic oscillations alters reproductive responses in many species. Aim of the study was to confirm whether effect of serotonergic drug (5-HTP) and dopaminergic drug (L-DOPA) is due to their conversion into serotonin and dopamine respectively or other products. For this study, PCPA (p-chlorophenylalanine, a long lasting inhibitor of serotonin synthesis), DDC (Diethyldithiocarbamate, which inhibits biosynthesis of nor-adrenaline), α-MT (Methyl-p-tyrosine, an inhibitor for the conversion of tyrosine to DOPA) and DOPS (Dihydroxyphenylserine, a specific precursor for noradrenaline) were used in different groups in addition to 5-HTP and L-DOPA given at specific time interval. Reproductive responses monitored at 10 weeks post treatment indicate that gonadal activity was significantly low in HTP:DOPA (8-hr quail), HTP+PCPA:DOPA and HTP:DOPA+DDC quail compare to control (S:S). However, gonadal activity of HTP:S(HTP control), S:DOPA(DOPA control) and HTP: α-MT+DOPS was not different from S:S control and remained in active condition. These findings indicate that it is not the dose of neurotransmitter precursor drugs (5-HTP and L-DOPA) and the neurotransmitters (serotonin and dopamine itself) that cause the effect, instead it is the function of interval between the drug administration which induces or entrains specific phase relation between serotonergic and dopaminergic oscillations. Further, gonadal suppression observed in HTP:DOPA, HTP+PCPA:DOPA and HTP:DOPA+DDC group three groups is not due to injection of 5-HTP or L-DOPA (alone) but due to conversion of administered 5-HTP into serotonin and conversion of L-DOPA (administered) into dopamine; not due to their further conversion into catecholamines other than dopamine i.e. noradrenaline or adrenaline.

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