Regulatory and Pathogenic Roles of Müller Glial Cells in Retinal Neovascular Processes and Their Potential for Retinal Regeneration

2009 ◽  
pp. 98-108 ◽  
Author(s):  
Astrid Limb ◽  
Hari Jayaram
Keyword(s):  
Glial Cells ◽  
Retinal Regeneration ◽  
Müller Glial Cells

scholarly journals BAC-Dkk3-EGFPTransgenic Mouse: AnIn VivoAnalytical Tool forDkk3Expression

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Yuki Muranishi ◽  
Takahisa Furukawa
Keyword(s):  
Transgenic Mice ◽  
Glial Cells ◽  
Wnt Signaling Pathway ◽  
Mouse Retina ◽  
Retinal Regeneration ◽  
Adult Retina ◽  
Müller Glial Cells ◽  
Mature Mouse ◽  
Precise Expression ◽  
Embryonic Retina

Dickkopf (DKK) family proteins are secreted modulators of the Wnt signaling pathway and are capable of regulating the development of many organs and tissues. We previously identifiedDkk3to be a molecule predominantly expressed in the mouse embryonic retina. However, which cell expressesDkk3in the developing and mature mouse retina remains to be elucidated. To examine the precise expression of theDkk3protein, we generatedBAC-Dkk3-EGFPtransgenic mice that express EGFP integrated into theDkk3gene in a BAC plasmid. Expression analysis using theBAC-Dkk3-EGFPtransgenic mice revealed thatDkk3is expressed in retinal progenitor cells (RPCs) at embryonic stages and in Müller glial cells in the adult retina. Since Müller glial cells may play a potential role in retinal regeneration,BAC-Dkk3-EGFPmice could be useful for retinal regeneration studies.

What do retinal Müller (glial) cells do for their neuronal ‘small siblings’?

1993 ◽  
Vol 6 (4) ◽  
pp. 201-213 ◽  
Author(s):  
A. Reichenbach ◽  
J.-U. Stolzenburg ◽  
W. Eberhardt ◽  
T.I. Chao ◽  
D. Dettmer ◽  
...  
Keyword(s):  
Glial Cells ◽  
Müller Glial Cells

GABAA receptor currents recorded from Müller glial cells of the baboon (Papio cynocephalus) retina

1996 ◽  
Vol 203 (3) ◽  
pp. 159-162 ◽  
Author(s):  
Winfried Reichelt ◽  
Miguel Hernandez ◽  
Raymond T. Damian ◽  
William S. Kisaalita ◽  
Berry L. Jordan
Keyword(s):  
Gabaa Receptor ◽  
Glial Cells ◽  
Papio Cynocephalus ◽  
Müller Glial Cells

Blood-derived macrophages infiltrate the retina and activate Muller glial cells under experimental choroidal neovascularization

2005 ◽  
Vol 81 (1) ◽  
pp. 38-47 ◽  
Author(s):  
Alejandro Caicedo ◽  
Diego G. Espinosa-Heidmann ◽  
Yolanda Piña ◽  
Eleut P. Hernandez ◽  
Scott W. Cousins
Keyword(s):  
Choroidal Neovascularization ◽  
Glial Cells ◽  
Müller Glial Cells

The glutathione content of retinal Müller (glial) cells: effect of pathological conditions

2000 ◽  
Vol 36 (4-5) ◽  
pp. 461-469 ◽  
Author(s):  
Dominik Huster ◽  
Andreas Reichenbach ◽  
Winfried Reichelt
Keyword(s):  
Glial Cells ◽  
Müller Glial Cells ◽  
Pathological Conditions

Voltage- and GABA-evoked currents from Müller glial cells of the baboon retina

Neuroreport ◽  
1997 ◽  
Vol 8 (2) ◽  
pp. 541-544 ◽  
Author(s):  
Winfried Reichelt ◽  
Miguel Hernandez ◽  
Raymond T. Damian ◽  
William S. Kisaalita ◽  
Berry L. Jordan
Keyword(s):  
Glial Cells ◽  
Müller Glial Cells

Immunocytochemical demonstration of glycogen phosphorylase in Müller (glial) cells of the mammalian retina

Glia ◽  
1994 ◽  
Vol 12 (1) ◽  
pp. 62-67 ◽  
Author(s):  
Brigitte Pfeiffer ◽  
Jens Grosche ◽  
Andreas Reichenbach ◽  
Bernd Hamprecht
Keyword(s):  
Glial Cells ◽  
Glycogen Phosphorylase ◽  
Müller Glial Cells ◽  
Mammalian Retina
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