The Relationship between Dental Caries and Tooth Enamel Fluoride

1985 ◽  
Vol 19 (5) ◽  
pp. 385-389 ◽  
Author(s):  
J.R. Mellberg ◽  
L.W. Ripa ◽  
G.S. Leske ◽  
M. Sanchez ◽  
R. Polanski
Keyword(s):  
Dental Caries ◽  
Tooth Enamel ◽  
The Relationship

scholarly journals sCD14 Level in Saliva of Children and Adolescents with and without Dental Caries, a Hurdle Model

Children ◽  
2021 ◽  
Vol 8 (8) ◽  
pp. 679
Author(s):  
Gaia Pellegrini ◽  
Marcello Maddalone ◽  
Matteo Malvezzi ◽  
Marilisa Toma ◽  
Massimo Del Fabbro ◽  
...  
Keyword(s):  
Dental Caries ◽  
Innate Immune ◽  
Hurdle Model ◽  
Soluble Cd14 ◽  
Clear Cut ◽  
Carious Lesions ◽  
Decayed Tooth ◽  
Group A ◽  
The Relationship ◽  
Control Study

Objective: Soluble CD14 (sCD14) plays an important role in the innate immune response of the oral cavity. The investigation of this biomarker for detection of carious lesions is an even more actual procedure due to its non-invasiveness and the ease of withdrawal. The purpose of the present observational case-control study was to evaluate whether the quantification of sCD14 in children and adolescent’s saliva can discriminate healthy subjects from those suffering from tooth decay. Materials and Methods: 164 subjects (6 to 17 years) were selected and divided into 2 groups: those with at least 1 decayed tooth were assigned to group Decayed (n = 82) and those free from dental caries to group Healthy (n = 82). The amount of salivary soluble CD14 was quantified. Results: Mean salivary soluble CD14 was 28.3 ± 10.8 μg/mL in the Healthy group and 22 ± 9.6 μg/mL in the Decayed group. A hurdle model was applied to the data to estimate both the probability of having carious lesions and their number in relation to sCD14 levels. sCD14 was strongly associated (p < 0.01) with an inverse relation to both the probability of having caries and their number (falling rate of 5% per unit CD14 μg/mL). Conclusions: This data confirms the relationship between sCD14 and the presence of dental caries. However, there is no clear cut off level between healthy and unhealthy subjects, so it is currently not possible to use sCD14 as a biomarker to determine the risk of decays.

scholarly journals Observational Study Regarding the Relationship between Nutritional Status, Dental Caries, Mutans Streptococci, and Lactobacillus Bacterial Colonies

2021 ◽  
Vol 18 (7) ◽  
pp. 3551
Author(s):  
Eugen Silviu Bud ◽  
Cristina Ioana Bica ◽  
Oana Elena Stoica ◽  
Alexandru Vlasa ◽  
Daniela Eșian ◽  
...  
Keyword(s):  
Dental Caries ◽  
Observational Study ◽  
Nutritional Status ◽  
Positive Association ◽  
Mutans Streptococci ◽  
Permanent Teeth ◽  
Deciduous Teeth ◽  
Dmft Index ◽  
The Relationship ◽  
Significant Health

The prevalence of dental caries and obesity is high as both raise significant health problems. The objective of this study was to evaluate the relationship between dental caries, the number of salivary colonies forming units of Mutans Streptococci (MS) and Lactobacillus (LB), and the nutritional status in a group of children from Transylvania. This observational study used a sample of 154 school children, aged 9 to 12 years. The prevalence of caries was measured using the decayed, missing, and filled teeth index for deciduous teeth (dmft index) and for permanent teeth (DMFT index). Height and weight were assessed for each subject, and their body mass index (BMI) percentile was calculated. Salivary levels of Mutans Streptococci (MS) and Lactobacillus (LB) were determined using the CRT Bacteria Test from Ivoclar Vivadent. In our study, we found a positive association between the BMI percentile, MS count, LB count, tooth brushing frequency, and the incidence of dental caries in children aged 9 to 12 years old. Future preventive programs should include nutrition control in order to prevent both the apparition of dental caries and obesity in children.

scholarly journals THE RELATIONSHIP BETWEEN DENTAL CARIES AND BODY MASS INDEX AMONG PRIMARY SCHOOL CHILDREN IN MAKKAH CITY

2017 ◽  
Vol 63 (2) ◽  
pp. 1099-1110
Author(s):  
Alamri Fahad ◽  
Alahmadi Abdulrahman ◽  
AlGhamdi Badr ◽  
Alghamdi Essam ◽  
Alqarni Anas ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Dental Caries ◽  
Primary School ◽  
Body Mass ◽  
School Children ◽  
Primary School Children ◽  
Makkah City ◽  
The Relationship

scholarly journals Antibiofilm Activity of Mangosteen (Garcinia mangostana L.) Flavonoids against Streptococcus mutans Bacteria

2020 ◽  
Vol 10 (2) ◽  
pp. 48
Author(s):  
Sri Kunarti ◽  
Aulia Ramadhani ◽  
Laskmiari Setyowati
Keyword(s):  
Dental Caries ◽  
Streptococcus Mutans ◽  
Tooth Enamel ◽  
Tooth Surface ◽  
Control Group ◽  
Antibiofilm Activity ◽  
Garcinia Mangostana ◽  
Control Group Design ◽  
Biofilm Inhibition ◽  
Significant Difference

Background: Dental caries is one of the most common infectious diseases and often occurs in the community caused by bacteria. Attached bacteria in the tooth surface for a long time will form a biofilm and will lead to demineralization characterized by damage in the structure of the tooth enamel. The bacteria that cause dental caries and can form biofilms is Streptococcus mutans. The bacteria inside biofilms are more resistant to antibacterial agents. Flavonoids in mangosteen pericarp extract can be a cleaner alternative for the anti-biofilm cavity that has properties against Streptococcus mutans. Purpose: To determine the activity of flavonoids in mangosteen pericarp extract at a certain concentration against Streptococcus mutans bacteria. Methods: This study was a laboratory experimental study with a post-test only control group design. Streptococcus mutans were diluted according to the Mc Farland dilution standard 106 in Tryptic Soy Broth (TSB) medium and put in a flexible U-bottom microtiter plate. Then it was incubated for 5x24 hours and checked using crystal violet simple staining to see the formation of biofilms. Flavonoid extract of mangosteen pericarp performed serial dilution in a concentration of 100%, 50%, 25%, 12.5%, 6.25%, 3.125%, 1.56%, and 0.78% was added, and the incubation process were conducted for 1x24 hours. OD (Optical Density) readings were done with a wavelength of 595 nm. Results: There was a significant difference between the test groups and the positive control group. The concentration of 100% had the anti-biofilm activity and showed the value of the highest percentage of inhibition, whilst the concentration of 0.78% showed a minimum biofilm inhibition concentration. The results were demonstrated by a statistical analysis test. Conclusion: Flavonoid extract of mangosteen pericarp at a certain concentration has anti-biofilm activity against Streptococcus mutans biofilm.

scholarly journals Relationship Between Salivary Nitric Oxide Concentration and Dental Caries in Children: A Systematic Review and Meta-Analysis

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Nadia Elyassi ◽  
Ali Malekzadeh Shafaroudi ◽  
Pegah Nasiri ◽  
Mahmood Moosazadeh ◽  
Azam Nahvi
Keyword(s):  
Nitric Oxide ◽  
Nitrous Oxide ◽  
Dental Caries ◽  
Meta Analysis ◽  
Control Group ◽  
Analysis Study ◽  
Oxide Concentration ◽  
The Mean ◽  
The Relationship ◽  
Nitrous Oxide Concentration

Context: Conflicting results have been reported in the literature concerning the relationship between salivary nitrous oxide concentration and dental caries in children. Metaanalysis studies aim to combine different studies and reduce the difference between the parameters by increasing the number of studies involved in the analysis process. Objectives: Accordingly, this meta-analysis study aimed at determining the relationship between salivary nitrous oxide concentration and dental caries in children. Methods: Databases were searched using the keywords “nitric oxide”, “salivary”, “Caries”, “DMFT Index”, “children”, “early childhood caries” and OR, AND and NOT operators. Quality assessment was then performed based on the Newcastle-Ottawa scale (NOS) checklist. The standardized mean difference (SMD) of DMFT, dmft, and salivary nitric oxide (NO) concentration was estimated. Results: Seven studies made a comparison between the mean salivary NO concentration in children with dental caries and that in the control group. In four studies, the mean salivary NO concentration in children with dental caries was lower, as compared to that in the control group. This difference was significant in all four studies. Also, the mean standardized difference of the salivary NO index was also estimated to be -0.11 (CI 95%: -1.77, 1.55). Conclusions: This meta-analysis study demonstrated that salivary NO concentration was not significantly related to dental caries. Moreover, since salivary NO concentration is affected by various factors, it is not sufficient to determine the likelihood of the incidence of caries.

scholarly journals Salivary protein glycopatterns for natural regulation of oral microbiota

2021 ◽  
Author(s):  
Zheng Li ◽  
Jian Shu ◽  
Yu Hanjie ◽  
Yan Wang ◽  
Xiameng Ren ◽  
...  
Keyword(s):  
Dental Caries ◽  
Microbial Communities ◽  
Salivary Protein ◽  
Host Factors ◽  
Oral Microbiota ◽  
Novel Theory ◽  
Dynamic Communities ◽  
Dietary Sugars ◽  
The Relationship

Abstract The oral microbiota is the direct precursor of dental caries and periodontitis, which are the most common microbial-induced diseases worldwide. The distinct microenvironment at the oral barrier breeds unique microbial communities, which are regulated by host factors (inflammation or dietary sugars)1. Increasing evidence indicates that dysbiosis of oral microbial communities is associated with many human diseases2-5. Our studies demonstrated that human disease could induce different alterations in salivary protein glycopatterns6. However, the relationship between salivary protein glycopatterns and oral microbial communities is unknown. Here, we report that altered salivary protein glycopatterns, namely, fucosylated or sialylated structures induced by gastric cancer (GC) or type 2 diabetes mellitus (T2DM), respectively, are also drivers of dysbiosis of oral microbial communities and ultimately dental caries and periodontitis. The fucosylated neoglycoproteins and sialic acid (SA) α2-3 galactose (Gal) structure can inhibit the growth or/and adhesion of Aggregatibacter segnis and Candida albicans from the oral cavity of patients with GC and T2DM, respectively. These findings provide a novel theory that dynamic communities of oral microbiota are regulated naturally by host salivary protein glycopatterns, having important implications for developing new carbohydrate drugs for oral and body health.

Caries risk in children: determined by levels of mutans streptococci and Lactobaccilus

2005 ◽  
Vol 29 (4) ◽  
pp. 329-333 ◽  
Author(s):  
Luis Alejandro Aguilera Galaviz ◽  
Gloria Premoli ◽  
Anajulia Gonzalez ◽  
Rafael Aguilar Rodriguez
Keyword(s):  
Dental Caries ◽  
Good Predictor ◽  
Risk Evaluation ◽  
Mutans Streptococci ◽  
Caries Risk ◽  
A Value ◽  
The Relationship

Lactobacullus sp. and S. mutans are microorganisms with cariogenic capacity, however, their presence do not determine the presence of dental caries.We evaluated the relationship between the presence of Lactobacillus sp. and S. mutans and dental caries in a schoolchildren population. The relation PIDMFT have a value of significance p = 0.001489. In dental caries risk evaluation, the S. mutans and Lactobacillus sp. detection in saliva is a good predictor and contributing to the caries development.

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