The Relationship between Body Mass Index, the Use of Second-Generation Antipsychotics, and Dental Caries among Hospitalized Patients with Schizophrenia

2011 ◽  
Vol 41 (4) ◽  
pp. 343-353 ◽  
Author(s):  
Kuan-Yu Chu ◽  
Nan-Ping Yang ◽  
Pesus Chou ◽  
Lin-Yang Chi ◽  
Hsien-Jane Chiu
2017 ◽  
Vol 63 (2) ◽  
pp. 1099-1110
Author(s):  
Alamri Fahad ◽  
Alahmadi Abdulrahman ◽  
AlGhamdi Badr ◽  
Alghamdi Essam ◽  
Alqarni Anas ◽  
...  

2016 ◽  
Vol 41 (3) ◽  
pp. 144-150
Author(s):  
Tahmina Zahan ◽  
Nargis Akhter ◽  
Mohammad Sayadul Islam Mullick ◽  
Zasmin Fauzia

The second generation antipsychotic agents, although exhibit superior safety profile, is associated with metabolic adverse effects including weight gain, diabetes mellitus and hyperlipidaemia. These adverse effects are not only the risk factors for cardiovascular disease and diabetes mellitus but may also impair patient’s adherence to treatment. However, different member of second generation antipsychotics differ in their extent of metabolic adverse effects. The aim of the study was to evaluate the association between olanzapine, risperidone or quetiapine treatment and body mass index, blood pressure, diabetes mellitus and hyperlipidaemia in patients with Schizophrenia and Bipolar Disorder. Forty-four cases of Schizophrenia and Bipolar Disorder diagnosed with DSM-IV criteria were selected according to inclusion and exclusion criteria. Body weight, body mass index and blood pressure were measured at baseline, at the end of 4th, 8th and 12th weeks of treatment. Blood samples were collected to measure blood glucose and serum lipid profile at baseline and at the end of 4th, 8th and 12th weeks in the study group receiving treatment (olanzapine 20-30 mg/day, risperidone 4-16 mg/day and quetiapine 300-800 mg/day) after overnight fasting. Therapeutic use of olanzapine and risperidone in Schizophrenia and Bipolar Disorder for a period of 4th, 8th and 12th weeks was associated with significant increase in body weight and body mass index. Quetiapine did not cause significant changes in body weight and body mass index after 4 and 8 weeks. However, after 12 weeks treatment, body mass index increased significantly. Olanzapine, risperidone and quetiapine increased the blood glucose level significantly after 8 and 12 weeks treatment. Olanzapine and risperidone elevated the serum cholesterol, triglyceride and low density lipoprotein levels significantly after 4, 8 and 12 weeks. But quetiapine showed no significant change in lipid profile. However, olanzapine and risperidone significantly increased triglyceride level after 8 and 12 weeks. Amongst three drugs, quetiapine treatment increased high density lipoprotein level. Our study revealed that quetiapine treatment is associated with less risk of dyslipidaemia.


2012 ◽  
Vol 22 (2) ◽  
pp. 166-173 ◽  
Author(s):  
Sjoerd de Hoogd ◽  
Wieske A. Overbeek ◽  
Eibert R. Heerdink ◽  
Christoph U. Correll ◽  
Elisabeth R. de Graeff ◽  
...  

2013 ◽  
Vol 52 (3) ◽  
pp. 336-343 ◽  
Author(s):  
Sameer R. Ghate ◽  
Christina A. Porucznik ◽  
Qayyim Said ◽  
Mia Hashibe ◽  
Elizabeth Joy ◽  
...  

2012 ◽  
Vol 15 (4) ◽  
pp. A82
Author(s):  
S.R. Ghate ◽  
C. Porucznik ◽  
Q. Said ◽  
E.A. Joy ◽  
M. Hashibe ◽  
...  

Author(s):  
Atefeh Pourfatahi ◽  
Hajar Atarzadeh ◽  
Forouzan Vahidi

Introduction: Dental caries is one of the most common chronic childhood diseases that have a profound impact on the health of both the individual and community health. The present study aimed to assess the relationship between Body Mass Index (BMI) and dental caries in Rafsanjan children aged 6-10 years in 2019. Materials & Methods: This study is a cross-sectional study that investigated the relationship between body mass index and dental caries in 215 male and female students (6-10 years old), selected by simple random sampling in four groups: slim, normal BMI, overweight, and obese the relationship between BMI and DMFT / dmft had been determined by Mann-Whitney and Kruskal-Wallis tests and Spearman correlation coefficient. Results: There was a significant inverse relationship between dmft index and children's body mass index (p value < 0.001, r = -0.315). There was no significant difference between the mean DMFT index between lean, normal weight, overweight and obese children (p value = 0.205) Conclusion: The dmft index decreased with increasing BMI, and there was no significant relationship between DMFT index and BMI. 


1970 ◽  
Vol 25 (1) ◽  
pp. 9-13
Author(s):  
S Jahan ◽  
TR Das ◽  
KB Biswas

Background and Aims: Cord blood leptin may reflect the leptinemic status of a newborn at birth more accurately than the leptin values of blood collected from other sites. The present study was undertaken to determine the relationship of cord serum leptin concentration at birth with neonatal and maternal anthropometric parameters. Materials and Methods: Blood was taken from the umbilical cord of the babies at delivery. Maternal anthropometric measurements were recorded at admission for delivery. Neonatal anthropometric measurements were recorded within 48 hours after delivery. Linear regression analysis was used to explore the relationship between cord serum leptin concentration and anthropometric parameters of the baby and the mother. Both Serum leptin and serum C-peptide levels were measured by chemiluminescence-based ELISA method. Results: The leptin concentration (ng/ml, mean±SD) in cord blood was 39.13±14.44. Cord leptin levels correlated with birth weight (r=0.673, p<0.0001), ponderal index (r=0.732, p<0.0001) but it did not correlate with maternal body mass index, gestational age (r=0.135, p=0.349) at delivery or cord serum C-peptide concentration (r=-0.049, p=0.735) or placental weight (r=0.203, p=0.157). Conclusion: There are associations between cord leptin concentration at delivery and birth weight, ponderal index (PI) of the babies but not body mass index (BMI) of the mothers. High leptin levels of the baby could represent an important feedback modulator of substrate supply and subsequently for adipose tissue status during late gestation. (J Bangladesh Coll Phys Surg 2007; 25 : 9-13)


Author(s):  
Ana P. Sehn ◽  
Anelise R. Gaya ◽  
Caroline Brand ◽  
Arieli F. Dias ◽  
Roya Kelishadi ◽  
...  

AbstractObjectivesThe combination of sleep duration, television (TV) time and body mass index (BMI) may be related to the alteration of cardiometabolic risk. However, there are few studies that use these variables grouped, and showing the moderating role of age. This study aimed to verify if the combination of sleep duration, TV time and BMI is associated with cardiometabolic risk and the moderating role of age in this relationship in youth.MethodsCross-sectional study conducted with 1411 adolescents (611 male), aged 10–17 years. Sleep duration, TV time and BMI were assessed and grouped into eight categories. Cardiometabolic risk was assessed by a continuous metabolic risk score, including the following variables: low HDL-cholesterol, elevated triglycerides, dysglycemia, high systolic blood pressure, high waist circumference and low cardiorespiratory fitness. Generalized linear models were used to test moderation of age in the relationship between the eight categories of sleep duration/television time/BMI with cardiometabolic risk.ResultsCardiometabolic risk factor showed association with all overweight or obesity independent of sleep time and TV time. Age moderated the relationship between sleep duration/television time/BMI with cardiometabolic risk. This association was stronger in younger adolescents (11 and 13 years), indicating that individuals with inadequate sleep, prolonged TV time and overweight/obesity present higher cardiometabolic risk values when compared to 15-year-old adolescents.ConclusionOverweight/obesity, independently of sleep duration and TV time, is the main risk factor for cardiometabolic disorders in adolescence. When moderated by age, younger adolescents that presented the combination of risk factors had higher cardiometabolic risk.


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