scholarly journals Single- and Multiple-Domain Amnestic Mild Cognitive Impairment: Two Sides of the Same Coin?

2009 ◽  
Vol 28 (6) ◽  
pp. 541-549 ◽  
Author(s):  
Simona Maria Brambati ◽  
Sylvie Belleville ◽  
Marie-Jeanne Kergoat ◽  
Céline Chayer ◽  
Serge Gauthier ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Amnestic Mild Cognitive Impairment ◽  
Two Sides ◽  
Multiple Domain

Cortical thickness in single- versus multiple-domain amnestic mild cognitive impairment

NeuroImage ◽  
2007 ◽  
Vol 36 (2) ◽  
pp. 289-297 ◽  
Author(s):  
Sang Won Seo ◽  
Kiho Im ◽  
Jong-Min Lee ◽  
Yun-Hee Kim ◽  
Sung Tae Kim ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cortical Thickness ◽  
Amnestic Mild Cognitive Impairment ◽  
Single Versus ◽  
Multiple Domain

Reaction time intra-individual variability reveals inhibitory deficits in single- and multiple-domain amnestic mild cognitive impairment

2021 ◽  
Author(s):  
Ricky Chow ◽  
Rahel Rabi ◽  
Shahier Paracha ◽  
Brandon P Vasquez ◽  
Lynn Hasher ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Response Inhibition ◽  
Individual Variability ◽  
Amnestic Mild Cognitive Impairment ◽  
Healthy Controls ◽  
Interference Control ◽  
Inhibitory Deficits ◽  
Report Data ◽  
Multiple Domain

Abstract Objectives Amnestic mild cognitive impairment (aMCI), a prodromal stage of Alzheimer’s disease and other dementias, is characterized by episodic memory impairment. Recent evidence has shown inhibitory control deficits in aMCI, but the extent of these deficits across inhibitory domains (i.e., response inhibition and interference control) and aMCI subtypes (i.e., single- versus multiple-domain) remains unclear. Few studies have included response time intra-individual variability (RT IIV) in these efforts. The aim of this study was to compare response inhibition and interference control between aMCI subtypes using measures of accuracy, mean RT, and RT IIV. Method We report data from 34 individuals with single-domain aMCI (sdaMCI, 66–86 years), 20 individuals with multiple-domain aMCI (mdaMCI, 68–88 years), and 52 healthy controls (64–88 years) who completed tasks of response inhibition (Go-NoGo) and interference control (Flanker). Group differences in accuracy, mean RT, and RT IIV were examined for both tasks. Results Individuals with mdaMCI had higher RT IIV than the other groups on both tasks. In RT IIV, we observed an interference control deficit in mdaMCI and sdaMCI relative to healthy controls, a finding not observed through accuracy or mean RT. Discussion RT IIV may detect subtle differences in inhibition deficits between aMCI subtypes that may not be evident with conventional behavioral measures. Findings support the supplementary use of RT IIV when assessing early executive function deficits.

scholarly journals Financial Capacity and Illiteracy: Does Education Matter in Amnestic Mild Cognitive Impairment?

2021 ◽  
pp. 1-5
Author(s):  
Vaitsa Giannouli ◽  
Magda Tsolaki
Keyword(s):  
Cognitive Impairment ◽  
High Education ◽  
Mild Cognitive Impairment ◽  
Formal Education ◽  
Amnestic Mild Cognitive Impairment ◽  
Potential Influence ◽  
Financial Capacity ◽  
Low Education ◽  
Amci Group ◽  
Multiple Domain

Neuropsychological assessment in amnestic mild cognitive impairment (aMCI) becomes complicated when education-literacy is taken into consideration. This study sought to explore the potential influence of literacy/illiteracy and education on financial capacity in patients with multiple-domain aMCI. Six groups consisting of aMCI (illiterate-no formal education, literate with low education, and literate with high education) and non-demented controls were examined. Literacy has an effect on financial capacity, as the illiterate aMCI group alone had the lowest scores in a financial capacity test resembling the performance of patients with mild Alzheimer’s disease. In controls there was a similar pattern, but all three healthy groups regardless of education scored above the cut-off score for incapacity.

scholarly journals Mapping the patterns of cortical thickness in single- and multiple-domain amnestic mild cognitive impairment patients: a pilot study

Aging ◽  
2019 ◽  
Vol 11 (22) ◽  
pp. 10000-10015 ◽  
Author(s):  
Pan Sun ◽  
Wutao Lou ◽  
Jianghong Liu ◽  
Lin Shi ◽  
Kuncheng Li ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Pilot Study ◽  
Cortical Thickness ◽  
Amnestic Mild Cognitive Impairment ◽  
Multiple Domain

The Five Systems of Dysphagia: MCI to the AD Spectrum of Disorders

2016 ◽  
Vol 1 (15) ◽  
pp. 37-52
Author(s):  
Jeanna Winchester ◽  
Carol G. Winchester
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Amnestic Mild Cognitive Impairment ◽  
Current Perspective ◽  
First Time ◽  
Multiple Domain

In order to swallow safely and effectively, there are five bodily systems that must work in coordination: Muscular, Respiratory, Neurological, Cognitive, and Gastrointestinal. Previously, these systems were established as the Five Systems of Dysphagia (5SysDys). Additionally, there exists an array of diseases/disorders that are linked to the development of Alzheimer's disease, and the current perspective proposes that these diseases/disorders can be referred to as the Alzheimer's Spectrum of Disorders (AD Spectrum). The current perspective proposes that the breakdown of the 5SysDys among patients suffering from the AD Spectrum is observable at the amnestic Mild Cognitive Impairment (aMCI) stage. Further, this perspective elucidates this relationship and distinguishes among the AD Spectrum, as well as proposes, for the first time in the literature, what types of 5SysDys breakdown is observable at the aMCI stage; aMCI is subdivided into the single and multiple domain diagnoses (SDaMCI & MDaMCI, respectively). We propose literature-driven conclusions and illustrate the importance of considering effective Dysphagia Management in the aMCI and AD Spectrum populations.

scholarly journals P-056: Cortical thickness in single- versus multiple-domain amnestic mild cognitive impairment

2007 ◽  
Vol 3 (3S_Part_1) ◽  
pp. S116-S116
Author(s):  
Sang Won Seo ◽  
Kiho Im ◽  
Jong-Min Lee ◽  
Yun-Hee Kim ◽  
Sung Tae Kim ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cortical Thickness ◽  
Amnestic Mild Cognitive Impairment ◽  
Single Versus ◽  
Multiple Domain
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