Verrucous Carcinoma of a Leg Amputation Stump

Dermatology ◽  
1991 ◽  
Vol 182 (3) ◽  
pp. 193-195 ◽  
Author(s):  
R.A. Schwartz ◽  
M.P. Bagley ◽  
C.K. Janniger ◽  
W.C. Lambert
Keyword(s):  
Verrucous Carcinoma ◽  
Amputation Stump ◽  
Leg Amputation

scholarly journals Verrucous Carcinoma of the Foot with Bone Invasion: A Case Report

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
C. Pempinello ◽  
A. Bova ◽  
R. Pempinello ◽  
R. Luise ◽  
G. Iannaci
Keyword(s):  
Early Stage ◽  
Verrucous Carcinoma ◽  
Focal Lesion ◽  
Multiple Biopsies ◽  
Pathological Evaluation ◽  
Delays In Diagnosis ◽  
Leg Amputation ◽  
Time Of Operation ◽  
Topical Medications ◽  
Chronic Course

Verrucous carcinoma of the foot often affects deep structures such as tendons, muscles, or bones. A 74-year-old man presented with a foot lesion that had been diagnosed as a skin infection 7 years earlier. He was treated with multiple excisions and superficial biopsies associated with antibiotic therapy without success. In our department he underwent an aggressive and accurate debridement with marginal excision harvesting multiple biopsies. Pathological evaluation of tissue at the time of operation confirmed the diagnosis of verrucous carcinoma of the foot. Therefore, the patient underwent an amputation below knee, and there were no postoperative complications; the patient was able to walk with the aid of a prosthesis with no signs of recurrence. The lesion follows a chronic course evolving from a discrete focal lesion to a large fungating deeply penetrating mass often compromised by local infection. The slow growth and confusing early-stage appearances can lead to delays in diagnosis of 8 to 15 years causing the extracutaneous involvement that requires a leg amputation. Many patients are initially treated with many topical medications without success, and most tumors have been treated as recalcitrant warts or corns for some time, whereas the basic approach is surgical.

Acute Shortening and Delayed Lengthening in Management of Lower Leg Amputation: A Case Report

2016 ◽  
Vol 25 (2) ◽  
pp. 65-68
Author(s):  
Seung Hoon Kang ◽  
Sung Won Jung ◽  
Jin Woo Jin ◽  
Dong Hee Kim ◽  
Sung Jin Shin ◽  
...  
Keyword(s):  
Case Report ◽  
Lower Leg ◽  
Acute Shortening ◽  
Lower Leg Amputation ◽  
Leg Amputation

Multidisciplinary Approach of a Very Rare Infected Verrucous Carcinoma of the Scrotum

2019 ◽  
Vol 70 (4) ◽  
pp. 1476-1478
Author(s):  
Laura Raducu ◽  
Adelaida Avino ◽  
Cristina-Nicoleta Cozma ◽  
Sorin Nedelea ◽  
Andra-Elena Balcangiu-Stroescu ◽  
...  
Keyword(s):  
Adjuvant Therapy ◽  
Rare Disease ◽  
Chronic Inflammation ◽  
Male Patient ◽  
Multidisciplinary Approach ◽  
Verrucous Carcinoma ◽  
Surgical Excision ◽  
Diagnosis And Treatment ◽  
Wide Surgical Excision ◽  
The Right

Verrucous carcinoma of the scrotum is an extremely rare disease and most cases are thought to result from poor hygiene and chronic inflammation. Currently, it has not been well characterized, the etiology, diagnosis and treatment remaining poorly understood. We present the case of a 50-year-old male patient diagnosed with verrucous carcinoma of the right hemiscrotum. Wide surgical excision was performed. Favorable outcomes can be achieved by surgery, even without any adjuvant therapy, but patients should be carefully followed up.

Oral Cancer: Raising Awareness of the Importance of Suspicion in Early Detection

2021 ◽  
Vol 10 (1) ◽  
pp. 10-12
Author(s):  
Farooq Ahmed ◽  
Honieh Bolooki ◽  
Senathrajah Ariyaratnam ◽  
Michael N. Pemberton
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cancer ◽  
Early Detection ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Verrucous Carcinoma ◽  
Mucosal Lesion ◽  
Morbidity And Mortality ◽  
Raising Awareness ◽  
Suspicious Lesions

Oral cancer is a significant cause of morbidity and mortality worldwide. In this article we present two cases of potentially innocuous looking lesions, initially thought to be traumatic in origin, but later diagnosed as cancer. The first patient presented with a persistent laceration thought to be caused by an accidental shaving injury, which was subsequently diagnosed as squamous cell carcinoma. The second patient presented with a hyperplastic mucosal lesion, suspected as forming due to denture-clasp irritation, which was subsequently diagnosed as proliferative verrucous carcinoma. The importance of early detection and palpation of suspicious lesions is emphasised in this article.

scholarly journals Pseudoepitheliomatous keratotic and micaceous balanitis: low-risk human papilloma virus detection in two further cases

2020 ◽  
pp. 095646242096194
Author(s):  
Marialuisa Corbeddu ◽  
Luca Pilloni ◽  
Roberta Satta ◽  
Laura Atzori ◽  
Franco Rongioletti
Keyword(s):  
Human Papillomavirus ◽  
Verrucous Carcinoma ◽  
Virus Detection ◽  
Low Risk ◽  
Hpv Testing ◽  
Papilloma Virus ◽  
Hpv Dna ◽  
Proliferative Markers ◽  
Male Patients ◽  
Papillomavirus Dna

We report two cases of histologically documented pseudoepitheliomatous keratotic and micaceous balanitis in middle-aged male patients, which showed positivity for low-risk serotype human papillomavirus DNA. To our knowledge, only one other case has been documented. Further immunohistochemical proliferative markers were performed and compared to literature findings in penile epithelial proliferations. Evolution to invasive verrucous carcinoma has been associated with absence of HPV DNA. Thus, if confirmed by further studies, HPV testing should be included in pseudoepitheliomatous keratotic and micaceous balanitis assessment to address prognosis, and management.

Research on miRNA-195 and target gene CDK6 in oral verrucous carcinoma

2017 ◽  
Vol 24 (7) ◽  
pp. 282-288 ◽  
Author(s):  
Z Deng ◽  
Y Wang ◽  
X Fang ◽  
F Yan ◽  
H Pan ◽  
...  
Keyword(s):  
Target Gene ◽  
Verrucous Carcinoma

scholarly journals Lengthening of an amputation stump by the Ilizarov technique

1997 ◽  
Vol 21 (4) ◽  
pp. 274-276 ◽  
Author(s):  
H. W. Park ◽  
J. S. Jahng ◽  
S. B. Hahn ◽  
D. E. Shin
Keyword(s):  
Ilizarov Technique ◽  
Amputation Stump

scholarly journals Intra-Abdominal Localisation of a Buschke-Lowenstein Tumour: Case Presentation and Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
N. E. Wester ◽  
E. M. Hutten ◽  
C. Krikke ◽  
Robert A. Pol
Keyword(s):  
Interferon Therapy ◽  
Verrucous Carcinoma ◽  
Treatment Options ◽  
Condyloma Acuminata ◽  
Review Of The Literature ◽  
Case Presentation ◽  
Advantages And Disadvantages ◽  
Literature Overview ◽  
Mucosal Surfaces ◽  
Tumour Reduction

Giant condyloma acuminatum or Buschke-Lowenstein tumour is a very rare disease which usually is located in the genital, anorectal, and perianal regions. It is regarded as a type of verrucous carcinoma occurring on anogenital mucosal surfaces where it is locally invasive but displays a benign cytology. We describe a case of a 24-year-old woman with persisting condyloma acuminata progressing to a large intra-abdominal Buschke-Lowenstein tumour. To our knowledge such an advanced stage has only been reported once before. The severity and extent of the tumour both determine the treatment and patient outcome. Treatment was impeded by cachexia, an immunosuppressive state after kidney transplantation and difficulties in establishing a reliable diagnose. Interferon treatment was started which initially led to tumour reduction but was complicated by an interferon-induced pancreatitis, pneumonia, and fasciitis necroticans resulting in death. We present a literature overview on the treatment options for a Buschke-Lowenstein tumour, with emphasis on interferon therapy, with all the advantages and disadvantages.

Reorganisation in human motor cortex

1995 ◽  
Vol 73 (2) ◽  
pp. 218-222 ◽  
Author(s):  
M. C. Ridding ◽  
J. C Rothwell
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Motor Cortex ◽  
Magnetic Stimulation ◽  
Voluntary Contraction ◽  
Short Latency ◽  
Human Motor Cortex ◽  
Amputation Stump ◽  
Human Motor

Transcranial magnetic stimulation over the motor cortex was used to construct a map of the effective sites on the scalp from which short-latency electromyogram responses could be evoked in muscles proximal to either an amputation stump (two subjects) or an ischemically anesthetized forearm (two subjects). At rest, the maps were larger and the responses bigger when stimulating contralateral to the amputated arm or after anesthesia than they were in the intact arm or before anesthesia. However, this difference disappeared when the maps were constructed during a small tonic voluntary contraction of the target muscle. We conclude that reorganisation of the corticospinal projection to a muscle at rest may no longer be present during activity. If so, this calls into question the possible functional benefits of such reorganisation in the control of movement after peripheral damage.Key words: motor cortex, magnetic stimulation, amputation, ischemia.

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