The Urinary Excretion of Homovanillic Acid and 4-Hydroxy 3-Methoxy Mandelic Acid in the Elderly Demented

1972 ◽  
Vol 14 (3) ◽  
pp. 172-175 ◽  
Author(s):  
R.H. Fisher
2014 ◽  
Vol 7 ◽  
pp. NMI.S12977 ◽  
Author(s):  
Karina Pfrimer ◽  
Rutinéia Fátima Micheletto ◽  
Julio Sergio Marchini ◽  
Gilberto João Padovan ◽  
Julio cesar Moriguti ◽  
...  

Project Data about the influence of aging on urinary excretion of iron and zinc are scarce. The objective of the present study was to compare the concentration of zinc and iron in the urine of healthy elderly subjects and younger adults. Procedure Seven healthy elderly subjects and seven younger adults were selected and submitted to biochemical, clinical, and nutritional tests. After a fasting period, 12-hour urine was collected for the determination of iron and zinc concentrations by graphite furnace atomic absorption spectrophotometry. Results Urinary zinc and iron concentrations of the elderly subjects were not significantly different from that of younger adults. However, the total zinc and iron urinary clearance in 24 hours for the elderly was significantly higher compared with that of younger adults. Conclusion There is an increase in urinary iron and zinc clearance with aging. The values reported in this manuscript may be used as references in future studies.


1974 ◽  
Vol 48 (s2) ◽  
pp. 295s-298s
Author(s):  
W. Januszewicz ◽  
B. Wocial

1. Urinary excretion of dopa, catecholamines and their metabolites (vanillylmandelic acid, methoxycatecholamines, 3-methoxy-4-hydroxyphenylglycol and homovanillic acid) were studied in eighty patients with essential hypertension and in twenty-five healthy control subjects. 2. Increased urinary excretion of catecholamines, dopa and catecholamine metabolites was found in a proportion of cases. 3. The relationship between urinary excretion of catecholamine metabolites and the excretion of dopa and noradrenaline was studied. 4. In view of the suggested significance of 3-methoxy-4-hydroxyphenylglycol as an index of brain catecholamine metabolism, particular attention was paid to urinary excretion of this metabolite in the subjects under study.


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