Effect of Subadequate Maternal Vitamin-A Status on Placental Transfer of Retinol and Beta-Carotene to the Human Fetus

Neonatology ◽  
1996 ◽  
Vol 69 (4) ◽  
pp. 230-234 ◽  
Author(s):  
R. Dimenstein ◽  
N.M.F. Trugo ◽  
C.M. Donangelo ◽  
L.C. Trugo ◽  
A.S. Anastácio
Keyword(s):  
Vitamin A ◽  
Human Fetus ◽  
Placental Transfer ◽  
Beta Carotene ◽  
Maternal Vitamin ◽  
Vitamin A Status

scholarly journals Impact of Maternal Daily Oral Low-Dose Vitamin A Supplementation on the Mother–Infant Pair: A Randomised Placebo-Controlled Trial in China

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2370
Author(s):  
Ye Ding ◽  
Ping Hu ◽  
Yue Yang ◽  
Fangping Xu ◽  
Fang Li ◽  
...  
Keyword(s):  
Health Status ◽  
Breast Milk ◽  
Vitamin A ◽  
Low Dose ◽  
Maternal Serum ◽  
Control Group ◽  
Vitamin A Supplementation ◽  
Maternal Vitamin ◽  
Vitamin A Status ◽  
Lactating Mothers

Background: The nutritional status of vitamin A in lactating mothers and infants is still not optimistic. Due to the dietary habits and dietary restrictions of postpartum customs in China, vitamin A supplementation has been advocated as a potential strategy to improve vitamin A status of lactating mothers with inadequate dietary vitamin A intake. Existing clinical trials are limited to single or double high-dose maternal administrations. However, in China, vitamin A supplements are readily available in the form of daily oral low-dose supplements, and the effect of these is unknown. This study aimed to evaluate the effects of daily oral low-dose vitamin A supplementation on the retinol levels in the serum and breast milk of lactating mothers and the health status of infants in China. Methods: Lactating mothers who met the inclusion criteria and planned to continue exclusive breastfeeding were randomly assigned to receive either daily oral vitamin A and D drops (one soft capsule of 1800 IU vitamin A and 600 IU vitamin D2), or a matching placebo for 2 months. Before and after the intervention, dietary intake was investigated by instant photography, and the retinol concentration in maternal serum and breast milk was determined by ultra-high performance liquid chromatography-tandem mass spectrometry. During the trial, the health status of infants was diagnosed by a paediatrician or reported by lactating mothers. A total of 245 participants completed the study, with 117 in the supplementation group and 128 in the control group. Results: After the 2-month intervention, maternal serum retinol concentrations increased in the supplementation group with no change in the control group. Although breast milk retinol concentrations decreased significantly in both groups, the decrease in the supplementation group was significantly lower than that in the control group. However, maternal vitamin A supplementation was not associated with a lower risk of infant febrile illness, respiratory tract infection, diarrhoea, and eczema. Conclusions: Daily oral low-dose vitamin A supplementation is helpful in improving maternal vitamin A status, despite having no effect on infant health status through breast milk.

THE STATUS OF BETA-CAROTENE AND VITAMIN A IN QUEBEC DAIRY HERDS: FACTORS AFFECTING THEIR STATUS IN COWS AND THEIR EFFECTS ON REPRODUCTIVE PERFORMANCE

1987 ◽  
Vol 67 (3) ◽  
pp. 775-788 ◽  
Author(s):  
ELLIOT BLOCK ◽  
BERTRAND FARMER
Keyword(s):  
Vitamin A ◽  
Reproductive Performance ◽  
Dairy Herd ◽  
Beta Carotene ◽  
Limiting Factor ◽  
Related Factors ◽  
Blood Samples ◽  
Factors Affecting ◽  
Vitamin A Status ◽  
The Status

Feed samples and a milk sample from the bulk tank were obtained from 100 randomly selected Holstein herds on the official option of the Dairy Herd Analysis Service, and jugular blood samples were obtained from five cows within each herd. Feed, milk and blood samples were analyzed for beta-carotene and grains, supplements, milk and blood for vitamin A. Haylage appeared to be the most reliable source of beta-carotene in comparison to dry hay and corn silage. The acid detergent fiber content of hay and/or haylage was shown to be negatively correlated to beta-carotene concentration. The concentrations of beta-carotene in the diet, plasma and milk were shown to be positively correlated; the same trends were observed for vitamin A. The concentrations of beta-carotene and vitamin A in plasma were shown to be negatively related. Factors affecting the concentrations of beta-carotene and vitamin A in plasma were examined. The beta-carotene and vitamin A status of a herd were shown to be both negatively correlated to calving interval and number of breedings per conception. Beta-carotene may only be expected to improve the fertility of a dairy herd when it is the most limiting factor. Additionally, the vitamin A status of a herd should always be considered when evaluating its beta-carotene status. Key words: Beta-carotene, vitamin A, reproductive performance, forage quality, cows (dairy)

scholarly journals A cluster-randomized, placebo-controlled, maternal vitamin a or beta-carotene supplementation trial in bangladesh: design and methods

Trials ◽  
2011 ◽  
Vol 12 (1) ◽  
Author(s):  
Alain B Labrique ◽  
Parul Christian ◽  
Rolf DW Klemm ◽  
Mahbubur Rashid ◽  
Abu Ahmed Shamim ◽  
...  
Keyword(s):  
Vitamin A ◽  
Beta Carotene ◽  
Maternal Vitamin ◽  
Cluster Randomized ◽  
Design And Methods

Use of Red Palm Oil for the Promotion of Maternal Vitamin A Status

2000 ◽  
Vol 21 (2) ◽  
pp. 215-218 ◽  
Author(s):  
G. Lietz ◽  
C. J. K. Henry ◽  
G. Mulokozi ◽  
J. Mugyabuso ◽  
A. Ballart ◽  
...  
Keyword(s):  
Vitamin A ◽  
Palm Oil ◽  
Maternal Vitamin ◽  
Red Palm Oil ◽  
Vitamin A Status

scholarly journals Determinants of Maternal Vitamin A or Beta-Carotene Supplementation Coverage: Village-Based Female Distributors in Nepal

2002 ◽  
Vol 92 (7) ◽  
pp. 1105-1107 ◽  
Author(s):  
Joanne Katz ◽  
Keith P. West ◽  
Lee Wu ◽  
Subarna K. Khatry ◽  
Elizabeth Kimbrough Pradhan ◽  
...  
Keyword(s):  
Vitamin A ◽  
Beta Carotene ◽  
Maternal Vitamin
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