Assessment of Fetal Rat Parathyroid Gland Activity during Hypocalcemia Induced by EDTA

Neonatology ◽  
1975 ◽  
Vol 27 (1-2) ◽  
pp. 115-120
Author(s):  
Jean-Michel Garel
2004 ◽  
Vol 44 (3) ◽  
pp. 476-480 ◽  
Author(s):  
Jose-Vicente Torregrosa ◽  
David Fuster ◽  
Juan Ybarra ◽  
Jaime Ortín ◽  
Agustín Moreno ◽  
...  

1972 ◽  
Vol 355 (4) ◽  
pp. 297-308 ◽  
Author(s):  
E. Alten�hr ◽  
F. Leonhardt

1970 ◽  
Vol 49 (9) ◽  
pp. 1619-1629 ◽  
Author(s):  
Shaul G. Massry ◽  
Jack W. Coburn ◽  
Charles R. Kleeman

1981 ◽  
Vol 111 (3) ◽  
pp. 514-524 ◽  
Author(s):  
Joellen Welsh ◽  
Ruth Schwartz ◽  
Lennart Krook

Author(s):  
F. G. Zaki

Fetal and neonatal liver injury induced by agents circulating in maternal plasma, even though well recognized, its morphological manifestations are not yet established. As part of our studies of fetal and neonatal liver injury induced by maternal nutritional disorders, metabolic impairment and toxic agents, the effects of two anti-inflammatory steroids have been recently inves tigated.Triamcinolone and methyl prednisolone were injected each in a group of rats during pregnancy at a-dosage level of 2 mgm three times a week. Fetal liver was studied at 18 days of gestation. Litter size and weight markedly decreased than those of control rats. Stillbirths and resorption were of higher incidence in the triamcinolone group than in those given the prednisolone.


Author(s):  
S.K. Aggarwal ◽  
J.M. Fadool

Cisplatin (CDDP) a potent antitumor agent suffers from severe toxic side effects with nephrotoxicity being the major dose-limiting factor, The primary mechanism of its action has been proposed to be through its cross-linking DNA strands. It has also been shown to inactivate various transport enzymes and induce hypocalcemia and hypomagnesemia that may be the underlying cause for some of its toxicities. The present is an effort to study its influence on the parathyroid gland for any hormonal changes that control calcium levels in the body.Male Swiss Wistar rats (Crl: (WI) BR) weighing 200-300 g and of 60 days in age were injected (ip) with cisplatin (7mg/kg in normal saline). The controls received saline injections only. The animals were injected (iv) with calcium (0.5 ml of 10% calcium gluconate/day) and were killed by decapitation on day 1 through 5. Trunk blood was collected in heparinized tubes.


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