Alveolar to Arterial Oxygen Tension Difference and Venous Admixture in Newly Born Infants with Congenital Diaphragmatic Herniation through the Foramen of Bochdalek

Neonatology ◽  
1971 ◽  
Vol 17 (3-4) ◽  
pp. 161-172 ◽  
Author(s):  
A.I. Murdock ◽  
J.B. Burrington ◽  
P.R. Swyer
1960 ◽  
Vol 15 (2) ◽  
pp. 253-254 ◽  
Author(s):  
M. Henry Williams

The percentage of venous admixture to arterialized blood was measured by two different techniques in two groups of patients with cirrhosis of the liver and, in both groups, averaged 9.7% of the cardiac output. Since one of the techniques was based on measurement of the arterial oxygen tension during oxygen breathing, the venous admixture must have resulted from some type of right-to-left shunt. It was not possible to determine whether the right-to-left shunt resulted from anastamoses between the portal system and the bronchopulmonary venous system or from pulmonary arteriovenous communications. Submitted on March 30, 1959


1978 ◽  
Vol 55 (1) ◽  
pp. 125-128 ◽  
Author(s):  
E. A. Harris ◽  
Eve R. Seelye ◽  
R.M.L. Whitlock

1. Data have been combined from three previous series to provide revised standards for the prediction of physiological dead-space volume (VD), arterial oxygen tension (Pa,o2), alveolar-to-arterial oxygen-tension difference (Pa,o2 - Pa,o2) and venous admixture fraction (Q̇va/Q̇t) in the sitting position. 2. These standards, based on measurements in 96 healthy men and women aged from 20 to 74 years, largely confirm conclusions drawn from the first series of 48 subjects. 3. VD is best predicted on age, height, tidal volume and the reciprocal of respiratory frequency. Pa,o2, (Pa,o2 - Pa,o2) and Q̇va/Q̇t are adequately predicted on age alone.


1964 ◽  
Vol 206 (4) ◽  
pp. 891-897 ◽  
Author(s):  
J. Hedley-Whyte ◽  
M. B. Laver ◽  
H. H. Bendixen

The rate and magnitude of the effects of the pressure-volume history of the lungs on the degree of physiologic shunting (pulmonary venous admixture) were investigated in 20 dogs, anesthetized and curarized. Atelectasis was promoted by decreasing end-expiratory transpulmonary pressure. Ventilation was with 100% oxygen using a constant-volume pump at a frequency of 20 breaths/min. The rates of increase or decrease in the physiologic shunt and of the gradients between derived alveolar oxygen tension and directly measured arterial oxygen tension (A-aD) showed a variation controlled by the pressure-volume history of the lungs. The physiologic shunts produced varied between 0.5% and 80% of the cardiac output. The interrelationships of the components of the shunt equation were studied and their relative value in predicting atelectasis was discussed. The data obtained were related to other observations made in anesthetized man.


1987 ◽  
Vol 25 (3) ◽  
pp. 199-208 ◽  
Author(s):  
STEVEN J. BARKER ◽  
KEVIN K. TREMPER

1996 ◽  
Vol 23 (2) ◽  
pp. 75-77
Author(s):  
P. Dobromylskyj ◽  
P.M. Taylor ◽  
J.C. Brearley ◽  
C.B. Johnson ◽  
S.P.L. Luna

PEDIATRICS ◽  
1972 ◽  
Vol 50 (2) ◽  
pp. 219-228
Author(s):  
Henrique Rigatto ◽  
June P. Brady

We studied nine healthy preterm infants during the first 35 days of life to define the relationship between periodic breathing, apnea, and hypoxia. For this purpose we compared ventilation/apnea (V/A), minute ventilation, and alveolar and capillary blood gases during periodic breathing induced by hypoxia and during spontancous periodic breathing in room air. We induced periodic breathing by giving the baby in sequence 21, 19, 17, and 15% O2 to breathe for 5 minutes each, and also by giving 21, 15, and 21% O2. We measured ventilation with a nosepiece and a screen flowmeter. With a decrease in arterial oxygen tension, preterm infants (1) hypoventilated, (2) breathed periodically more frequently, and (3) showed a decrease in V/A due to an increase in the apneic interval. In one baby this led to apnea lasting 30 seconds. These findings support our hypothesis that preterm infants breathing periodically hypoventilate and suggest that hypoxia may be a primary event leading to periodic breathing and apnea.


1974 ◽  
Vol 85 (2) ◽  
pp. 254-261 ◽  
Author(s):  
Arnold W. Strauss ◽  
Marilyn Escobedo ◽  
David Goldring

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