Adhesion of Lymphocytes to Endothelial Cells in Experimental Allergic Encephalomyelitis before and after Treatment with Endotoxin Lipopolysaccharide

1995 ◽  
Vol 106 (4) ◽  
pp. 335-344 ◽  
Author(s):  
Masayuki Matsuda ◽  
Naoyuki Tsukada ◽  
Koichi Miyagi ◽  
Nobuo Yanagisawa
Keyword(s):  
Endothelial Cells ◽  
Experimental Allergic Encephalomyelitis ◽  
Allergic Encephalomyelitis ◽  
Before And After ◽  
Experimental Allergic

scholarly journals Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element.

1987 ◽  
Vol 166 (6) ◽  
pp. 1906-1911 ◽  
Author(s):  
D J Hinrichs ◽  
K W Wegmann ◽  
G N Dietsch
Keyword(s):  
Bone Marrow ◽  
Endothelial Cells ◽  
Endothelial Cell ◽  
Experimental Allergic Encephalomyelitis ◽  
Adoptive Transfer ◽  
Spleen Cells ◽  
Allergic Encephalomyelitis ◽  
Cytotoxic Cells ◽  
Bone Marrow Chimeras ◽  
Experimental Allergic

The adoptive transfer of clinical and histopathologic signs of experimental allergic encephalomyelitis (EAE) requires MHC compatibility between cell donor and cell recipient. The results of adoptive transfer studies using F1 to parent bone marrow chimeras as recipients of parental-derived BP-sensitive spleen cells indicate that this restriction is not expressed at the level of the endothelial cell but is confined to the cells of bone marrow derivation. Furthermore, these results indicate that the development of EAE is not dependent on the activity of MHC-restricted cytotoxic cells.

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