Ultracytochemical localization of alkaline phosphatase activity in endothelial cells in chronic relapsing experimental allergic encephalomyelitis

1987 ◽  
Vol 73 (3) ◽  
pp. 220-226 ◽  
Author(s):  
S. Kato ◽  
H. Nakamura
Keyword(s):  
Alkaline Phosphatase ◽  
Endothelial Cells ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Experimental Allergic Encephalomyelitis ◽  
Allergic Encephalomyelitis ◽  
Experimental Allergic

scholarly journals Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element.

1987 ◽  
Vol 166 (6) ◽  
pp. 1906-1911 ◽  
Author(s):  
D J Hinrichs ◽  
K W Wegmann ◽  
G N Dietsch
Keyword(s):  
Bone Marrow ◽  
Endothelial Cells ◽  
Endothelial Cell ◽  
Experimental Allergic Encephalomyelitis ◽  
Adoptive Transfer ◽  
Spleen Cells ◽  
Allergic Encephalomyelitis ◽  
Cytotoxic Cells ◽  
Bone Marrow Chimeras ◽  
Experimental Allergic

The adoptive transfer of clinical and histopathologic signs of experimental allergic encephalomyelitis (EAE) requires MHC compatibility between cell donor and cell recipient. The results of adoptive transfer studies using F1 to parent bone marrow chimeras as recipients of parental-derived BP-sensitive spleen cells indicate that this restriction is not expressed at the level of the endothelial cell but is confined to the cells of bone marrow derivation. Furthermore, these results indicate that the development of EAE is not dependent on the activity of MHC-restricted cytotoxic cells.

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