Heparin-Containing Mast Cells in the Jejunal Mucosa of Normal and Parasitized Mongolian Gerbils, Meriones unguiculatus

1992 ◽  
Vol 98 (4) ◽  
pp. 415-419 ◽  
Author(s):  
Y. Horii ◽  
N. Ishikawa ◽  
Y. Nawa
Keyword(s):  
Mast Cells ◽  
Meriones Unguiculatus ◽  
Jejunal Mucosa ◽  
Mongolian Gerbils

scholarly journals Cloning of the cDNAs for mast-cell chymases from the jejunum of Mongolian gerbils, Meriones unguiculatus, and their sequence similarities with chymases expressed in the connective-tissue mast cells of mice and rats

1996 ◽  
Vol 314 (3) ◽  
pp. 923-929 ◽  
Author(s):  
Hiroshi ITOH ◽  
Yuko MURAKUMO ◽  
Masaki TOMITA ◽  
Hisamitsu IDE ◽  
Takahiko KOBAYASHI ◽  
...  
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Connective Tissue ◽  
Mongolian Gerbil ◽  
Meriones Unguiculatus ◽  
Amino Acid Sequences ◽  
Jejunal Mucosa ◽  
Mongolian Gerbils ◽  
Mast Cell Protease ◽  
Mucosal Mast Cells

By using the combination of reverse-transcription PCR and rapid amplification of cDNA ends methods, two distinct cDNAs encoding mast-cell proteases (chymases; MCPs), designated as gMCP-1 and -2, were successfully cloned and sequenced from the jejunum of Mongolian gerbil, Meriones unguiculatus, infected with Nippostrongylus brasiliensis. On the basis of a comparison of the deduced amino acid sequences with those of known rodent mast-cell chymases, gMCP-1 was found to be highly similar to mouse mast-cell protease (mMCP)-4 and rat mast-cell protease (rMCP)-1, while gMCP-2 was similar to mMCP-5 and rMCP-3. Although mMCP-4 and -5 and rMCP-1 and -3 were restrictedly or mainly expressed in connective-tissue mast cells and serosal mast cells, the gMCP-1 and -2 genes were mainly transcribed in the jejunal mucosa and to a lesser extent in the skin and tongue. Moreover, kinetic study after infection revealed that the amounts of the gMCP-1 and -2 mRNAs in jejunum paralleled well the degree of intestinal mastocytosis. The expression of gMCP-1 and -2 in mucosal mast cells of gerbil jejunum was also confirmed by in situ hybridization. Since a tryptase, another type of MCP, was also expressed in mucosal mast cells of gerbils but not in those of mice and rats, the expression of MCPs in mucosal mast cells of gerbils is different from those of mice and rats. The Mongolian gerbil would be a useful model with which to investigate the physiopathological role of MCPs.

scholarly journals Bioavailability of β-carotene (βC) from purple carrots is the same as typical orange carrots while high-βC carrots increase βC stores in Mongolian gerbils(Meriones unguiculatus)

2006 ◽  
Vol 96 (2) ◽  
pp. 258-267 ◽  
Author(s):  
Mandy Porter Dosti ◽  
Jordan P. Mills ◽  
Philipp W. Simon ◽  
Sherry A. Tanumihardjo
Keyword(s):  
Public Health ◽  
Vitamin A ◽  
Phenolic Acids ◽  
Health Problem ◽  
Public Health Problem ◽  
Meriones Unguiculatus ◽  
Mongolian Gerbils ◽  
Alternative Source ◽  
Β Carotene

Vitamin A (VA) deficiency is a worldwide public health problem. Biofortifying existing sources of β-carotene (βC) and increasing dietary βC could help combat the issue. Two studies were performed to investigate the relative βC bioavailability of a βC supplement to purple, high-βC orange, and typical orange carrots using Mongolian gerbils (Meriones unguiculatus). In study 1, which used a traditional bioavailability design, gerbils (n32) received a diet containing orange, purple, or white carrot powder, or white carrot powder +a βC supplement. In study 2, which included βC-biofortified carrots, gerbils (n 39) received orange, high-βC orange, purple, or white carrot powder in their diet. Both studies lasted 21 d and the gerbils were killed to determine the effect of carrot type or supplement on serum and liver βC, α-carotene, and VA concentrations. Liver stores of βC or VA in the gerbils did not differ between orange and purple carrot diets when equal amounts of βC from each of the diets were consumed (P>0·05). Both the orange and purple carrot diet resulted in higher liver VA compared with the supplement (P<0·05). High-βC carrots resulted in more than 2-fold higher βC and 1·1 times greater VA liver stores compared with typical orange carrots (P<0·05). These results suggest that high-βC carrots may be an alternative source of VA to typical carrots in areas of VA deficiency. Second, phenolics including anthocyanins and phenolic acids in purple carrot do not interfere with the bioavailability of βC from purple carrots.

The effect of sand deprivation on sandbathing and marking in Mongolian gerbils (Meriones unguiculatus)

1974 ◽  
Vol 11 (3) ◽  
pp. 403-407 ◽  
Author(s):  
Daniel F. Tortora ◽  
Jerry C. Eyer ◽  
Stephen R. Overmann
Keyword(s):  
Meriones Unguiculatus ◽  
Mongolian Gerbils

Intra- and Interspecific Observational Learning in Rats

1975 ◽  
Vol 37 (1) ◽  
pp. 241-242 ◽  
Author(s):  
Russell A. Benel
Keyword(s):  
Observational Learning ◽  
Meriones Unguiculatus ◽  
Operant Response ◽  
Albino Rats ◽  
Mongolian Gerbils

Observational learning of an operant response by male albino rats was compared under two modelling conditions. The interspecific models were Mongolian gerbils ( Meriones unguiculatus). There were no significant differences between the groups either in trials to acquisition or total responses. Possible limitations to the generalizability of these results were noted.

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