Dendritic Cell Accumulation in Draining Lymph Nodes during the Induction Phase of Contact Allergy in Mice

1989 ◽  
Vol 89 (2-3) ◽  
pp. 202-210 ◽  
Author(s):  
A. Kinnaird ◽  
S.W. Peters ◽  
J.R. Foster ◽  
I. Kimber
Keyword(s):  
Dendritic Cell ◽  
Lymph Nodes ◽  
Contact Allergy ◽  
Induction Phase ◽  
Cell Accumulation ◽  
Draining Lymph Nodes

scholarly journals Defective early innate immune response to ectromelia virus in the draining lymph nodes of aged mice due to impaired dendritic cell accumulation

Aging Cell ◽  
2020 ◽  
Vol 19 (7) ◽  
Author(s):  
Colby Stotesbury ◽  
Eric B. Wong ◽  
Lingjuan Tang ◽  
Brian Montoya ◽  
Cory J. Knudson ◽  
...  
Keyword(s):  
Immune Response ◽  
Dendritic Cell ◽  
Lymph Nodes ◽  
Innate Immune Response ◽  
Innate Immune ◽  
Ectromelia Virus ◽  
Aged Mice ◽  
Cell Accumulation ◽  
Draining Lymph Nodes

scholarly journals Repeated Antigen Challenge Modulates Expression of Follicular Dendritic Cell (FDC) Related Molecule in Draining Lymph Nodes.

2001 ◽  
Vol 34 (4) ◽  
pp. 265-273 ◽  
Author(s):  
Yoshiaki Ohmori ◽  
Toshiko Yoshida ◽  
Motonori Okabe ◽  
Kenichi Takaya ◽  
Fumitomo Koizumi ◽  
...  
Keyword(s):  
Dendritic Cell ◽  
Lymph Nodes ◽  
Follicular Dendritic Cell ◽  
Antigen Challenge ◽  
Related Molecule ◽  
Follicular Dendritic ◽  
Draining Lymph Nodes

Exogenous dendritic cell homing to draining lymph nodes can be boosted by mast cell degranulation

2010 ◽  
Vol 263 (2) ◽  
pp. 204-211 ◽  
Author(s):  
Shu-Rong Ren ◽  
Li-Bin Xu ◽  
Zhi-Yuan Wu ◽  
Jun Du ◽  
Mei-Hua Gao ◽  
...  
Keyword(s):  
Mast Cell ◽  
Dendritic Cell ◽  
Lymph Nodes ◽  
Mast Cell Degranulation ◽  
Cell Homing ◽  
Draining Lymph Nodes

scholarly journals CCR8 regulates contact hypersensitivity by restricting cutaneous dendritic cell migration to the draining lymph nodes

2014 ◽  
Vol 27 (4) ◽  
pp. 169-181 ◽  
Author(s):  
Rikio Yabe ◽  
Kenji Shimizu ◽  
Soichiro Shimizu ◽  
Satoe Azechi ◽  
Byung-Il Choi ◽  
...  
Keyword(s):  
Cell Migration ◽  
Dendritic Cell ◽  
Lymph Nodes ◽  
Contact Hypersensitivity ◽  
Dendritic Cell Migration ◽  
Draining Lymph Nodes

scholarly journals Dendritic Cell Populations in Leishmania major-Infected Skin and Draining Lymph Nodes

2004 ◽  
Vol 72 (4) ◽  
pp. 1991-2001 ◽  
Author(s):  
Tracey Baldwin ◽  
Sandrine Henri ◽  
Joan Curtis ◽  
Meredith O'Keeffe ◽  
David Vremec ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Dendritic Cell ◽  
Lymph Nodes ◽  
Leishmania Major ◽  
Mouse Skin ◽  
Parasite Load ◽  
Plasmacytoid Dendritic Cells ◽  
Cell Populations ◽  
Infection Model ◽  
Draining Lymph Nodes

ABSTRACT Using a metacyclic promastigote ear infection model of cutaneous leishmaniasis, we examined the phenotype, parasite load, and cytokine production of dendritic cells in the skin and draining lymph nodes of resistant C57BL/6J and susceptible BALB/c mice. Five dendritic cell populations were isolated from the skin and lymph nodes, and the main difference between the groups of mice was an increased number of plasmacytoid dendritic cells in the lymph nodes of the susceptible mice. Although similar cell types were present in the skin emigrants of both strains, there was a 10-fold larger number of cells in BALB/c mouse skin early in infection than in C57BL/6J mouse skin. None of the dendritic cells in the lymph nodes harbored parasites until 3 weeks after infection, with the Langerhans cells having the largest load and the plasmacytoid dendritic cells having the smallest load but the longest lasting infection. Although parasites could be detected in the lymph nodes a few hours after infection, none of the skin emigrants harbored parasites, indicating that they are not the vehicle that ferries the parasites from the skin to the lymph nodes. The presence of larger numbers of plasmacytoid cells in infected BALB/c mice, the more protracted infection of these cells, and their production of alpha interferon point to a complex and important role for the plasmacytoid cells in leishmaniasis.

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