In vitro Release of Eosinophil Chemotactic Factor of Anaphylaxis (ECF-A) from Guinea Pig Skin

1979 ◽  
Vol 60 (4) ◽  
pp. 465-468 ◽  
Author(s):  
Isamu Kimura ◽  
Shoso Yamamoto ◽  
Takuso Yamura
Keyword(s):  
Guinea Pig ◽  
Chemotactic Factor ◽  
Pig Skin ◽  
Eosinophil Chemotactic Factor

scholarly journals Effect of Neutrophil-derived Eosinophil Chemotactic Factor (ECF) in Human and Guinea Pig Skin

1980 ◽  
Vol 74 (2) ◽  
pp. 109-111 ◽  
Author(s):  
Bean M. Czarnetzki ◽  
Peter J. Frosch ◽  
Fereydoun Vakilzadeh ◽  
Wolfgang B. Panneck
Keyword(s):  
Guinea Pig ◽  
Chemotactic Factor ◽  
Pig Skin ◽  
Eosinophil Chemotactic Factor

scholarly journals In Vitro Anaphylaxis In Guinea-Pig Skin: Amplification By Burimamide

1976 ◽  
Vol 67 (6) ◽  
pp. 696-699 ◽  
Author(s):  
Shoso Yamamoto ◽  
David Francis ◽  
Malcolm W Greaves
Keyword(s):  
Guinea Pig ◽  
Pig Skin

Release of peptide leukotrienes(LTS) from sensitized guinea pig skin in in vitro cutaneous anaphylactic reactions

1991 ◽  
Vol 2 (3) ◽  
pp. 232
Author(s):  
Tsunemi Numata ◽  
Kiyoshi Furutani ◽  
Isamu Kimura ◽  
Satoru Yamada ◽  
Shoso Yamamoto
Keyword(s):  
Guinea Pig ◽  
Pig Skin

The interaction between tetracycline and reconstituted guinea-pig-skin collagen in vitro

1964 ◽  
Vol 86 (3) ◽  
pp. 579-587 ◽  
Author(s):  
Richard Jacobs ◽  
William H. Harris ◽  
Elton P. Katz ◽  
Melvin J. Glimcher
Keyword(s):  
Guinea Pig ◽  
Pig Skin ◽  
Skin Collagen

scholarly journals Toxicity and medical countermeasure studies on the organophosphorus nerve agents VM and VX

2015 ◽  
Vol 471 (2176) ◽  
pp. 20140891 ◽  
Author(s):  
Helen Rice ◽  
Christopher H. Dalton ◽  
Matthew E. Price ◽  
Stuart J. Graham ◽  
A. Christopher Green ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Penetration Rate ◽  
Lethal Dose ◽  
Scientific Advice ◽  
Complete Protection ◽  
Pig Skin ◽  
Syrian Arab Republic ◽  
Medical Countermeasures

To support the effort to eliminate the Syrian Arab Republic chemical weapons stockpile safely, there was a requirement to provide scientific advice based on experimentally derived information on both toxicity and medical countermeasures (MedCM) in the event of exposure to VM, VX or VM–VX mixtures. Complementary in vitro and in vivo studies were undertaken to inform that advice. The penetration rate of neat VM was not significantly different from that of neat VX, through either guinea pig or pig skin in vitro . The presence of VX did not affect the penetration rate of VM in mixtures of various proportions. A lethal dose of VM was approximately twice that of VX in guinea pigs poisoned via the percutaneous route. There was no interaction in mixed agent solutions which altered the in vivo toxicity of the agents. Percutaneous poisoning by VM responded to treatment with standard MedCM, although complete protection was not achieved.

Sign in / Sign up

Export Citation Format

Share Document