Suppression of the Leukocyte Adherence Inhibition Response to Murine-Sarcoma-Virus-Induced Tumors by Tumor-Associated Suppressor Cells

Oncology ◽  
1980 ◽  
Vol 37 (6) ◽  
pp. 406-410 ◽  
Author(s):  
Richard F. Mortensen ◽  
Lawrence M. Elson
1979 ◽  
Vol 6 (3) ◽  
pp. 137-141 ◽  
Author(s):  
T. Sanner ◽  
P. Eker ◽  
R. Eker ◽  
J. Mossige

1972 ◽  
Vol 139 (1) ◽  
pp. 279-285 ◽  
Author(s):  
A. F. Gazdar ◽  
A. J. Weinstein ◽  
H. L. Sims ◽  
A. D. Steinberg

1983 ◽  
Vol 69 (4) ◽  
pp. 299-303 ◽  
Author(s):  
Utpala Chattopadhyay ◽  
Surajit Guha

Tube leukocyte adherence-inhibition response to syngeneic mammary tumor antigens and alloantigens from Ehrlich ascites carcinoma and fibrosarcoma was studied in spontaneous mammary tumor-bearing C3H/Jax mice. The mice with limited tumor burden responded significantly to the mammary tumor antigen and the Ehrlich ascites carcinoma antigen. The reactivity disappeared with increased tumor load. Oscillatory responses in leukocyte adherence inhibition to the reactive antigens was observed with increasing tumor weight. There was no response to the alloantigen of fibrosarcoma.


Author(s):  
R. A. Al-Adhami ◽  
A. L. Chapman

Fujinaga et al reported MSV induced rat and hamster osteosarcoma which showed an occassional unusual bud in the rat induced tumors. Savage and Hackett and Hackett and Sylvester reported abnormal type C virus in UCLB cells derived from Balb/3t3 cells infected and transformed with MLV. They wer unable to demonstrate sarcoma virus activity. Fischinger and O‘Connor reported the infection of cat embryo cells by a centrifugally induced aggregate of murine sarcoma virus and feline leukemia virus designated as MSV(FelLV). This virus gave rise to a defective, focus forming virus which propagated in cat cells but not in mouse cells.In the present study the morphoiogy of the MSV(FelLV) virus obtained from Dr. Fischinger and maintained in our laboratory since 1970 will be reported. Feline embryo fibroblasts (established in our lab.) and Crandall feline kidney cells (Cutter-Haver-Lockhart, Shawnee, Kansas) were used in this study.


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