Soy Consumption Reduces Risk of Ischemic Stroke: A Case-Control Study in Southern China

2009 ◽  
Vol 33 (2) ◽  
pp. 111-116 ◽  
Author(s):  
Wenbin Liang ◽  
Andy H. Lee ◽  
Colin W. Binns ◽  
Rongsheng Huang ◽  
Delong Hu ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Case Control Study ◽  
Southern China ◽  
Case Control ◽  
Control Study

Habitual Physical Activity Reduces the Risk of Ischemic Stroke: A Case-Control Study in Southern China

2009 ◽  
Vol 28 (5) ◽  
pp. 454-459 ◽  
Author(s):  
Wenbin Liang ◽  
Andy H. Lee ◽  
Colin W. Binns ◽  
Qingkun Zhou ◽  
Rongsheng Huang ◽  
...  
Keyword(s):  
Physical Activity ◽  
Ischemic Stroke ◽  
Case Control Study ◽  
Southern China ◽  
Case Control ◽  
Habitual Physical Activity ◽  
Control Study

scholarly journals Correlation between matrix metalloproteinase-2 polymorphisms and first and recurrent atherosclerotic ischemic stroke events: a case–control study

2021 ◽  
Vol 49 (6) ◽  
pp. 030006052110229
Author(s):  
Ying Li ◽  
Qing-rong Ouyang ◽  
Juan Li ◽  
Xiao-rong Chen ◽  
Lin-lin Li ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Matrix Metalloproteinase ◽  
Chinese Population ◽  
Case Control Study ◽  
Case Control ◽  
Matrix Metalloproteinase 2 ◽  
Odds Ratios ◽  
Control Study

Objective To determine the associations between matrix metalloproteinase-2 (MMP-2, encoded by the MMP2 gene) 1306C/T and 735C/T polymorphisms and first and recurrent ischemic stroke in a Chinese population. Methods Patients with first and recurrent ischemic stroke were included. Serum MMP-2 was measured, and MMP2 1306C/T and 735C/T polymorphisms were detected. The associations between MMP2 1306C/T and 735C/T polymorphisms and first and recurrent ischemic stroke were analyzed. Results Serum MMP-2 in patients with first and recurrent ischemic stroke was significantly higher compared with controls, and patients with recurrent ischemic stroke had higher MMP-2 than those with first ischemic stroke. The frequency of the CC genotype and C allele of MMP2 735C/T was highest in patients with recurrent ischemic stroke, followed by patients with first ischemic stroke, and controls. Conversely, the genotype and allele of MMP2 1306C/T did not significantly differ between groups. The CC genotype of MMP2 735C/T was independently associated with first and recurrent ischemic stroke (odds ratios = 1.45 and 1.64, respectively), as was the C allele of MMP2 735C/T (odds ratios = 1.68 and 1.77, respectively). Conclusions The CC genotype and C allele of MMP2 735C/T were associated with first and recurrent ischemic stroke in a Chinese population.

scholarly journals Habitual physical activity reduces risk of ovarian cancer: A case–control study in southern China

2013 ◽  
Vol 57 ◽  
pp. S31-S33 ◽  
Author(s):  
Andy H. Lee ◽  
Dada Su ◽  
Maria Pasalich ◽  
Yut Lin Wong ◽  
Colin W. Binns
Keyword(s):  
Physical Activity ◽  
Ovarian Cancer ◽  
Case Control Study ◽  
Southern China ◽  
Case Control ◽  
Habitual Physical Activity ◽  
Control Study

scholarly journals AChRAb and MuSKAb double-seropositive myasthenia gravis: a distinct subtype?

2021 ◽  
Vol 42 (3) ◽  
pp. 863-869
Author(s):  
Jieni Zhang ◽  
Yin Chen ◽  
Jiaxin Chen ◽  
Xin Huang ◽  
Haiyan Wang ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Case Control Study ◽  
Southern China ◽  
Case Control ◽  
Disease Subtype ◽  
Bulbar Dysfunction ◽  
Control Study ◽  
Worse Prognosis ◽  
Distinct Subtype ◽  
Immunosuppressant Treatment

Abstract Introduction This study investigated the characteristics of double-seropositive myasthenia gravis (DSP-MG) in southern China for disease subtype classification. Methods A case-control study was carried out in which the characteristics of DSP-MG patients (n = 17) were compared to those of muscle-specific tyrosine kinase antibody-positive (MuSK)-MG and acetylcholine receptor antibody-positive (AChR)-MG patients (n = 8 and 27, respectively). We also performed a literature review of DSP-MG patients. Results Compared to AChR-MG, DSP-MG had greater bulbar dysfunction (47.1% vs 18.6%, P = 0.04), higher incidence of myasthenia crisis (41.2% vs 14.8%, P = 0.04), more severe Myasthenia Gravis Foundation of America classification at maximum worsening, greater autoantibody abnormalities (70.6% vs 33.3%, P = 0.015), greater need for immunosuppressant treatment (58.8% vs 3.7%, P < 0.001), and worse prognosis with less remission (11.8% vs 55.6%, P = 0.001). There were no differences between DSP-MG and MuSK-MG patients. DSP-MG described in published reports was comparable to MuSK-MG. Discussion DSP-MG in southern China may be a subtype of MuSK-MG.

scholarly journals Risk of ischemic stroke associated to analgesic drugs use: a real world data case-control study

2018 ◽  
Vol 26 ◽  
pp. S225
Author(s):  
R. Vives ◽  
A. Gomez-Lumbreras ◽  
M. Fradera ◽  
M. Giner-Soriano ◽  
A. Garcia-Sangenis ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Real World ◽  
Case Control Study ◽  
Case Control ◽  
Real World Data ◽  
Analgesic Drugs ◽  
World Data ◽  
Control Study

Abstract NS2: Effect of Volume-Viscosity Swallow Test (V-VST) in Acute Ischemic Stroke Patients With Dysphagia: A Hospital-Based Case-Control Study

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Ting Ye ◽  
Yi Dong ◽  
Shengyan Huang
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Case Control Study ◽  
Tube Feeding ◽  
Case Control ◽  
Stroke Patients ◽  
Post Intervention ◽  
Post Stroke ◽  
Volume Viscosity ◽  
Control Study

Background: The dysphagia screening in acute ischemic stroke plays an important role in patients with risk of dysphagia. The aim of this hospital-based case-control study is to explore if V-VST, as a new nurse-driven dysphagia screening tool for AIS patients, might help to reduce the rate of post-stroke pneumonia and early withdraw of feeding tube. Methods: 1598 acute ischemic stroke patients were enrolled in this study. The standard protocol in AIS patients were assessed by WST (before intervention and plus with V-VST after intervention). The V-VST assessment were be trained in two senior nurses and all AIS patients were assessed by V-VST during July 1and Dec 30 th , 2017. Among 299 AIS patients with suspected, all clinical data were analyzed. The comparison of their rate of pneumonia in hospital and withdraw rate of tubefeeding before discharge were performed between patients post-intervention (January 1, 2018-June 30, 2019)and those admitted before the intervention (January 1, 2016-June 30, 2017). Results: The baseline characteristics of the pre- and post- intervention AIS groups were similar in age, gender, NIHSS. The implementation of V-VST have a statistically significant reducing the risk of pneumonia with an adjusted HR (0.60, 95% CI 0.43-0.84, P=0.003). Additionally, follow-up V-VST were likely to be associated the withdraw rate of tube-feeding at discharge (29/168 vs 38/131 P=0.016).There is also a trend of length of tube-feeding decreasing (8.32±12.27 vs 6.84±8.61 P=0.241). Conclusion: In our study, the V-VST is a feasible bedside tool. The implemental might be associated with the reduction of post-stroke pneumonia. Therefore, it meets the requirements of a clinical screening test for dysphagia in acute stroke patients at bedside. Large prospective interventional study is needed to confirm our findings. V-VST: Volume-viscosity Swallow Test WST: Water Swallow Test AIS: Acute Ischemic Stroke HR: hazard ratio

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