Topotecan (Hycamtin®): Potent Cytostatic Action by Selective Topoisomerase I Inhibition

1997 ◽  
Vol 20 (5) ◽  
pp. 380-386 ◽  
Author(s):  
J. von Pawel
Keyword(s):  
Topoisomerase I ◽  
Cytostatic Action

11-Phenylundeca-5Z,9Z-dienoic Acid: Stereoselective Synthesis and Dual Topoisomerase I/IIα Inhibition

2015 ◽  
Vol 15 (6) ◽  
pp. 504-510 ◽  
Author(s):  
Vladimir D’yakonov ◽  
Lilya Dzhemileva ◽  
Aleksey Makarov ◽  
Alfiya Mulyukova ◽  
Dmitry Baevd ◽  
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Keyword(s):  
Topoisomerase I ◽  
Stereoselective Synthesis ◽  
Dienoic Acid

Synthesis and Biological Evaluation of 1,5-Naphthyridines as Topoisomerase I Inhibitors. A New Family of Antiproliferative Agents

2015 ◽  
Vol 14 (23) ◽  
pp. 2722-2728 ◽  
Author(s):  
Concepcion Alonso ◽  
Maria Fuertes ◽  
Maria Gonzalez ◽  
Alicia Rodriguez-Gascon ◽  
Gloria Rubiales ◽  
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Keyword(s):  
Topoisomerase I ◽  
Biological Evaluation ◽  
Antiproliferative Agents ◽  
Topoisomerase I Inhibitors ◽  
New Family ◽  
Synthesis And Biological Evaluation

Investigation of Isoindolo[2,1-a]quinoxaline-6-imines as Topoisomerase I Inhibitors with Molecular Modeling Methods

2017 ◽  
Vol 13 (3) ◽  
Author(s):  
Balazs Balogh ◽  
Anna Carbone ◽  
Virginia Spanò ◽  
Alessandra Montalbano ◽  
Paola Barraja ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Topoisomerase I ◽  
Modeling Methods ◽  
Topoisomerase I Inhibitors
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