Malignant Fibrous Histiocytoma of Bone and Soft Tissue – Two Different Tumor Entities? A Retrospective Study of 45 Cases

1995 ◽  
Vol 18 (6) ◽  
pp. 573-579 ◽  
Author(s):  
H. Mau ◽  
V. Ewerbeck ◽  
P. Reichardt ◽  
L. Bernd ◽  
D. Sabo
Keyword(s):  
Retrospective Study ◽  
Soft Tissue ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Tumor Entities

LOCAL RECURRENCES AFTER THE TREATMENT OF SOFT TISSUE MALIGNANT FIBROUS HISTIOCYTOMA (UNCLASSIFIEDPLEOMORPHIC SARCOMA) OF THE LIMBS

2019 ◽  
Vol 72 (8) ◽  
pp. 1523-1526
Author(s):  
Oleksandr O. Lytvynenko ◽  
Volodymyr F. Konovalenko ◽  
Anton Yu. Ryzhov
Keyword(s):  
Soft Tissue ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Survival Rates ◽  
Soft Tissue Sarcomas ◽  
Primary Treatment ◽  
Radical Excision ◽  
Local Recurrences ◽  
Results Of Treatment

Introduction: The treatment of patients with malignant fibrous histiocytoma as well as other soft tissue sarcomas is not sufficiently effective up to date, and has largely changed and reflects the alterations, occurred in oncology as a whole. The number of amputation decreased over the last 10-15 years. Some researchers associate the improvement of treatment outcomes with the development of combined and complex methods. The aim of the study is an improvement of the results of treatment of patients with soft tissue malignant histiocytoma on the basis of determination of factors, influencing local recurrence development. Materials and methods: The basis of our study was a comprehensive analysis of examination and treatment results of 130 patients with MFH of the soft tissue of limbs, of them in 84 patients (64.6%) the recurrences developed. The group included 45 (53.6%) males and 39 (46.4%) females. The major part of patients – 82.1% (60 patients) were older than 40 years. Results and conclusions: The number of recurrences after the treatment in general surgical facilities is 86.9%, whereas in the patients after the treatment in the specialized oncological facilities this figure is twice lower (40%). The characteristic of the medical facility where the patient receives his/her primary treatment largely affects the development of local recurrences, patients’ quality of life and overall survival rates. The surgical method remains the leading modality in the treatment of MFH of ST. Wide and radical excision of tumors in the specialized oncological facilities allows achieving better survival outcomes of the patients.

Rare Case of Malignant Fibrous Histiocytoma of the Bladder Associated with Microinfiltrating Transitional Cell Carcinoma

1998 ◽  
Vol 65 (1_suppl) ◽  
pp. 89-92
Author(s):  
F. Di Nuovo ◽  
O. Privitera ◽  
R. Bonacina ◽  
G. Catania ◽  
M. Sironi ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Malignant Fibrous Histiocytoma ◽  
Carcinoma In Situ ◽  
Rare Case ◽  
Fibrous Histiocytoma ◽  
Transitional Cell ◽  
Soft Tissue Tumours

Although malignant fibrous histiocytoma is the most common among soft tissue tumours in adults, its origin in the bladder is extremely rare. Only 17 cases have been reported so far. We present the case of an 86-year-old patient who, following clinical and instrumental examination for a large bladder growth, underwent partial cystectomy. The histopathological exam showed a neoplastic mass, while immunohistochemical findings indicated a malignant fibrous histiocytoma. A transitional cell carcinoma in situ with microinfiltration of the lamina propria was also observed near the above tumour.

scholarly journals Oral Health and Molecular Aspects of Malignant Fibrous Histiocytoma Patients: A Systematic Review of the Literature

2020 ◽  
Vol 17 (4) ◽  
pp. 1426
Author(s):  
Khrystyna Zhurakivska ◽  
Giuseppe Troiano ◽  
Marco Montella ◽  
Lorenzo Lo Muzio ◽  
Luca Fiorillo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Soft Tissue ◽  
Malignant Fibrous Histiocytoma ◽  
Soft Tissues ◽  
Fibrous Histiocytoma ◽  
Case Reports ◽  
Soft Tissue Sarcomas ◽  
Clinical Aspects ◽  
Risk Of Death ◽  
Short Period

Malignant fibrous histiocytoma is one of the most common soft tissue sarcomas in adults. It occurs only occasionally in oral soft tissues, and knowledge about its characteristics is based on a limited number of cases reported in the literature. Malignant fibrous histiocytoma belongs to the group of soft tissue sarcomas and makes up less than 10% of soft tissue sarcomas. For therapeutic purposes, complete exeresis of the lesion (macroscopic and microscopic) is performed because they have frequent recurrences. As for complementary therapy in addition to surgery, neither radiotherapy nor chemotherapy have been shown to reduce the risk of death related to the disease. Often patients complain of a swelling that grows in a short period of time. It is quite common for patients to report trauma in the area, which is not the cause, but rather the event that allows diagnosis. The mass usually does not cause pain unless it compresses an adjacent nerve structure. The aim of this study is to systematically review the scientific literature in order to identify the most recent studies concerning malignant fibrous histiocytomas localized in oral soft tissues and report their main data. The main outcomes of this study concern the immunohistochemical, molecular, and clinical aspects of this pathology. A systematic review of articles in the electronic databases pubmed, Scopus, and Web of Science was performed. After the selection process, 11 studies met the inclusion criteria and were included in the review. The mean age of the patients was 50.8 years old. The lesions affected various parts of the oral cavity, showing predominantly storiform–pleomorphic patterns. All cases except one were treated with surgical resection and radiation therapy. Although some data emerged from this review, they remain limited to a few case reports. Further studies are necessary in order to standardize the approach to patients affected by oral malignant fibrous histiocytoma (MFH).

Cytologic diagnosis for the malignant fibrous histiocytoma of the subcutaneous soft tissue and its related diseases.

1985 ◽  
Vol 24 (3) ◽  
pp. 426-439
Author(s):  
Masahiko KAKIHANA ◽  
Yasusi OHOKUBO ◽  
Masahiro URASAKI ◽  
Kikue NOHARA ◽  
Noriko FUKUSHIMA ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Cytologic Diagnosis

Benign Fibrous Histiocytoma: Report of Case

2003 ◽  
Vol 4 (2) ◽  
pp. 74-79 ◽  
Author(s):  
Ümit Ertaş ◽  
M. Cemil Büyükkurt ◽  
Yasin Çiçek
Keyword(s):  
Soft Tissue ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Panoramic Radiograph ◽  
Giant Cells ◽  
Benign Fibrous Histiocytoma ◽  
Multinucleated Giant Cells ◽  
Caucasian Male ◽  
Storiform Pattern ◽  
Radiolucent Lesion

Abstract Benign fibrous histiocytoma is a rare and usually painless oral neoplasm found in adults that may affect either soft tissue or bone typically noted in their fifth decade. This case was found in a 32 year-old Caucasian male who presented with a fairly well circumscribed unilocular radiolucent lesion extending from the mandibular right first incisor to the left first premolar and reaching the inferior mandible on a panoramic radiograph. A bony window was created and the intrabony lesion was curetted. Multiple sections revealed a cellular tumor composed of uniform spindle-shaped cells arranged in a prominent whorled or storiform pattern. Scattered xanthoma cells, multinucleated giant cells, lymphocytes, and deposits of hemosiderin were noted throughout the lesional stroma. Although malignant fibrous histiocytoma of the bone is relatively well known, benign fibrous histiocytoma of the bone is very rare. Citation Ertas U, Büyükkurt MC. Benign Fibrous Histiocytoma: Report of Case. J Contemp Dent Pract 2003 May;(4)2:074-079.

scholarly journals Gene expression analysis of soft tissue sarcomas: characterization and reclassification of malignant fibrous histiocytoma

2007 ◽  
Vol 20 (7) ◽  
pp. 749-759 ◽  
Author(s):  
Robert Nakayama ◽  
Takeshi Nemoto ◽  
Hiro Takahashi ◽  
Tsutomu Ohta ◽  
Akira Kawai ◽  
...  
Keyword(s):  
Gene Expression ◽  
Soft Tissue ◽  
Expression Analysis ◽  
Malignant Fibrous Histiocytoma ◽  
Gene Expression Analysis ◽  
Fibrous Histiocytoma ◽  
Soft Tissue Sarcomas

scholarly journals A Huge Soft Tissue Malignant Fibrous Histiocytoma Successfully Treated by Combination of Irradiation and Chemotherapy. A Report of a Case.

1997 ◽  
Vol 46 (4) ◽  
pp. 1217-1219
Author(s):  
Koichiro Yokoyama ◽  
Norio Shinohara ◽  
Satoshi Hanamura ◽  
Koji Kubota ◽  
Osamu Nagatsu ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma
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