Association of Single Nucleotide Polymorphisms in the Eosinophil Peroxidase Gene with Allergic Rhinitis in the Czech Population

2009 ◽  
Vol 150 (2) ◽  
pp. 184-191 ◽  
Author(s):  
Barbara Hrdlickova ◽  
Lydie Izakovicova-Holla
Keyword(s):  
Allergic Rhinitis ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Czech Population ◽  
Peroxidase Gene ◽  
Eosinophil Peroxidase

Association of Single Nucleotide Polymorphisms in the Eosinophil Peroxidase Gene with Japanese Cedar Pollinosis

2004 ◽  
Vol 135 (1) ◽  
pp. 40-43 ◽  
Author(s):  
Hiroyuki Nakamura ◽  
Fumiko Higashikawa ◽  
Kiyoshi Miyagawa ◽  
Yoshitaka Nobukuni ◽  
Tomohiko Endo ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Japanese Cedar ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Peroxidase Gene ◽  
Eosinophil Peroxidase ◽  
Japanese Cedar Pollinosis

Association of interleukin 6 single nucleotide polymorphisms with allergic rhinitis

2014 ◽  
Vol 78 (9) ◽  
pp. 1426-1429 ◽  
Author(s):  
Rasoul Nasiri ◽  
Masoud Movahedi ◽  
Ali Akbar Amirzargar ◽  
Armin Hirbod-Mobarakeh ◽  
Elham Farhadi ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Single Nucleotide Polymorphisms ◽  
Interleukin 6 ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

Association of single nucleotide polymorphisms in GATA-3 with allergic rhinitis

2009 ◽  
Vol 129 (2) ◽  
pp. 190-194 ◽  
Author(s):  
Luo Zhang ◽  
Luo Zhang ◽  
Xiangdong Wang ◽  
Demin Han ◽  
Hong Duan ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

scholarly journals Identification of single nucleotide polymorphisms in FOXJ1 and their association with allergic rhinitis

2006 ◽  
Vol 51 (4) ◽  
pp. 292-297 ◽  
Author(s):  
Chun-Shi Li ◽  
Soo-Cheon Chae ◽  
Jae-Hoon Lee ◽  
Qinggao Zhang ◽  
Hun-Taeg Chung
Keyword(s):  
Allergic Rhinitis ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

scholarly journals HIF-1α Pulmonary Phenotype Wide Association Study Unveils a Link to Inflammatory Airway Conditions

2021 ◽  
Vol 12 ◽  
Author(s):  
Jelte Kelchtermans ◽  
Xiao Chang ◽  
Michael E. March ◽  
Frank Mentch ◽  
Patrick M. A. Sleiman ◽  
...  
Keyword(s):  
Experimental Data ◽  
Allergic Rhinitis ◽  
Single Nucleotide Polymorphisms ◽  
Association Study ◽  
Acute Bronchitis ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Disease Associations

Despite experimental data linking HIF-1α dysfunction to inflammatory airway conditions, the effect of single nucleotide polymorphisms within the HIF1A gene on these conditions remains poorly understood. In the current study, we complete a phenotype wide association study to assess the link between SNPs with known disease associations and respiratory phenotypes. We report two SNPs of the HIF1A gene, the intronic rs79865957 and the missense rs41508050. In these positions the A and the T allele are significantly associated with allergic rhinitis and acute bronchitis and bronchiolitis, respectively. These findings further support the role of HIF-1α in inflammatory pulmonary conditions and may serve as a basis to refine our understanding of other HIF-1α associated phenotypes.

scholarly journals Association of IL-4 Polymorphisms with Allergic Rhinitis in Jordanian Population

Medicina ◽  
2020 ◽  
Vol 56 (4) ◽  
pp. 179
Author(s):  
Baeth Moh’d Al-Rawashdeh ◽  
Ahmed Sadaalhanjori ◽  
Elnagi Ali ◽  
Malek Zihlif
Keyword(s):  
Allergic Rhinitis ◽  
Single Nucleotide Polymorphisms ◽  
Allelic Frequency ◽  
Population Variation ◽  
Interleukin 4 ◽  
Control Group ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Minor Alleles ◽  
Polymerase Chain

Background and objectives: Allergic rhinitis has complex patterns of inheritance, and single nucleotide polymorphisms, a common genetic variation in a population, exert a significant role in allergic rhinitis pathology. The current study aimed to investigate the association of Interleukin-4 (IL-4) polymorphisms with allergic rhinitis. Materials and Methods: Our study included 158 patients with allergic rhinitis and 140 healthy controls from Jordan that were genotyped for IL-4 single nucleotide polymorphisms (SNPs) C-589T (rs2243250) and T-2979G (rs2227284) using restriction fragment length polymorphism-polymerase chain reaction. Statistical analysis was conducted using IBM SPSS Statistics version 24 software. Results: The results showed that the allelic frequency of the minor alleles was 0.19 and 0.67 for C-589T (rs2243250) and T-2979G (rs2227284) in the allergic rhinitis patients, respectively, while it was 0.18 for C-589T (rs2243250) and 0.64 T-2979G (rs2227284) in the control group. The homozygous (TT) genotype of C-589T (rs2243250) was significantly associated with allergic rhinitis (p < 0.05), while there was no association of any of T-2979G (rs2227284) genotypes with allergic rhinitis. Conclusions: The results of this study indicate that genetic inter-population variation precipitates the differences in the percentages of many diseases among populations, including allergic rhinitis.

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