Guidance of Technical Management of Dialysis Water and Dialysis Fluid for the Japan Association for Clinical Engineering Technologists

2009 ◽  
Vol 27 (1) ◽  
pp. 41-49 ◽  
Author(s):  
Tadayuki Kawasaki ◽  
Junji Uchino ◽  
Toshio Shinoda ◽  
Hideki Kawanishi
Keyword(s):  
Clinical Engineering ◽  
Dialysis Fluid ◽  
Technical Management ◽  
Dialysis Water

Fully Automated Clinical Engineering Technical Management System

2006 ◽  
Vol 31 (1) ◽  
pp. 46-60 ◽  
Author(s):  
Iyad Mobarek ◽  
Waleed Al Tarawneh ◽  
Francois Langevin ◽  
Mohammad Ibbini
Keyword(s):  
Management System ◽  
Clinical Engineering ◽  
Technical Management

scholarly journals The level of endotoxins in hemodialysis water and dialysate in Lithuanian hemodialysis centers

Medicina ◽  
2010 ◽  
Vol 46 (8) ◽  
pp. 556 ◽  
Author(s):  
Inga Skarupskienė ◽  
Inga Bumblytė ◽  
Donatas Tamošaitis ◽  
Jūratė Venterienė ◽  
Vytautas Kuzminskis
Keyword(s):  
Best Practice ◽  
Dialysis Fluid ◽  
Membrane Pores ◽  
Best Practice Guidelines ◽  
Bacterial Endotoxins ◽  
Pass Through ◽  
Definition Of ◽  
Dialysis Water ◽  
Limulus Amebocyte Lysate Test

The composition and quality of the dialysis fluid play an important role in the modulation of dialysis-related complications. During hemodialysis, patient’s blood has a contact with dialysate through a semipermeable membrane. Bacterial endotoxins can pass through the membrane pores into the patient’s blood and cause a silent chronic microinflammation. The aim of this study was to determine the level of endotoxins in hemodialysis water and dialysate in Lithuanian hemodialysis centers. Dialysis water (n=50) and dialysate (n=50) were collected from 91% (n=50) of all hemodialysis centers. The presence of bacterial endotoxins was evaluated using a sensitive Limulus amebocyte lysate test, which detects intact lipopolysaccharides. The level of endotoxins was lower than 0.25 EU/mL in 43 (86%) dialysis water samples and in 46 (92%) dialysate samples, and complied with the recommendations of the European Pharmacopoeia and the European Best Practice Guidelines for pure dialysis fluid. The dialysate of 39 (78%) Lithuanian hemodialysis centers complied with the definition of an ultrapure dialysis fluid. The water and dialysate were of insufficient quality in 14% and in 8% of Lithuanian hemodialysis centers, respectively, and this could be improved by the establishment of routine investigation of endotoxins.

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