The kava plant, Piper methysticum Forst. f., is an attractive shrub in the pepper family, Piperaceae (figure 12.1). Known by various names in tropical Pacific, such as yagona, kava, kava kava, ’awa, seka, and sakau, it is propagated vegetatively, as are most of the traditional crops in the region. Kava has been used for many centuries to produce psychoactive preparations. Its active principles, several lipidlike substances known as kavalactones, are concentrated in the rootstock and roots. These psychoactive chemicals are ingested traditionally by Pacific islanders as cold-water infusions of chewed, ground, pounded, or otherwise macerated kava stumps and roots. Mind-altering kava preparations are, or once were, imbibed in a wide range of Pacific Ocean societies. These include peoples living in some lowland areas on the large Melanesian island of New Guinea in the western Pacific to very isolated islands such as those in Polynesian Hawai’i, 7,000 kilometers to the northeast (figure 12.2). Beyond this widespread local use in the tropical Pacific, utilization of kava in parts of Europe as a plant source for medicinal preparations has a relatively lengthy history. In Europe it has been used as a sedative, tranquilizer, muscle relaxant, relief from menopausal symptoms, and treatment for urinary tract and bladder ailments (Lebot et al. 1999). Over the past decade, there has been rapidly increasing interest in kava well beyond the areas of traditional use among Pacific Islanders (figure 12.3). This includes a huge surge in the use of kava products in Europe, North America, Australia, and elsewhere. Within the past 3 to 5 years there has been widespread recognition of its potential to emerge as a mainstream herbal product. Modern cultivation and use of kava in the Pacific has significantly expanded in some traditional use areas such as Vanuatu, Fiji, Tonga, Samoa, and Pohnpei. There are also significant signs of rejuvenated interest in kava cultivation in some traditional areas of use where it had been abandoned because of depopulation, political prohibition, or zealous missionary denunciation. Increasing use and cultivation of kava on these Pacific islands has been stimulated by local consumption rates and rising demand for commercial export.
Neuroprotective profile of Piper Methysticum (Kava Kava) and its effects on the Central Nervous System: a systematic review