Role of Genetic Factors in Lower- and Higher-Order Aberrations – The Genes in Myopia Twin Study

2009 ◽  
Vol 41 (3) ◽  
pp. 142-147 ◽  
Author(s):  
M. Dirani ◽  
M. Chamberlain ◽  
T.A. Couper ◽  
R.H. Guymer ◽  
P.N. Baird
2015 ◽  
Vol 70 (5) ◽  
pp. 647-653 ◽  
Author(s):  
Renata Bogo ◽  
Ahmed Farah ◽  
Ann-Christin Johnson ◽  
Kjell K. Karlsson ◽  
Nancy L. Pedersen ◽  
...  
Keyword(s):  

1976 ◽  
Vol 25 (1) ◽  
pp. 218-220
Author(s):  
Carla Candelori ◽  
Anna Oliverio Ferraris ◽  
Paolo Parisi

A sample of 27 MZ and 32 DZ twin pairs, aged 6 to 12 years, has been tested with the Draw A Family Test. Significantly higher concordance values in MZ than DZ twins have been found with respect to some graphic-structural factors (i.e.: line, hand pressure, area of the drawing, dimensions of the figures, distribution, and shading) as well as with respect to contents factors, such as spatial representation and cotwin's valorization. These correlates of personality development would thus appear to undergo significant genetic conditioning.


1974 ◽  
Vol 23 (S2) ◽  
pp. 37-37
Author(s):  
C. Candelori ◽  
A. Oliverio-Ferraris ◽  
P. Parisi
Keyword(s):  

2015 ◽  
Vol 56 (6) ◽  
pp. 3919 ◽  
Author(s):  
Dong Hui Lim ◽  
Woori Kim ◽  
Gyule Han ◽  
Gi Hyun Bae ◽  
Myung Hun Kim ◽  
...  

1985 ◽  
Vol 147 (1) ◽  
pp. 48-53 ◽  
Author(s):  
Kenneth S. Kendler

SummarySubstantial evidence suggests that genetic factors contribute to the aetiology of both schizophrenia and alcoholism, when they occur alone. To examine the role of genetic factors in schizophrenia and alcoholism when they occur together in the same individual, the frequency of both conditions was investigated in the co-twins of 34 monozygotic (MZ) and 47 dizygotic (DZ) index twins with a diagnosis of both schizophrenia and alcoholism. Both disorders alone were significantly more common in the MZ than in the DZ co-twins, suggesting that individuals suffering from schizophrenia and alcoholism have a genetic predisposition to both disorders, which is of the same nature as that which causes the two when they occur alone. In the co-twins of the MZ index twins, the diagnoses of schizophrenia and alcoholism were uncorrelated, indicating that the specific environmental factors of causal importance in the two disorders are not closely related.


GYNECOLOGY ◽  
2019 ◽  
Vol 21 (3) ◽  
pp. 9-16
Author(s):  
Nataly I Frolova ◽  
Tatiana E Belokrinitskaya

Background. Miscarriage is a common complication in early pregnancy. Current studies have shown a higher prevalence of miscarriage, ranging from 10 to 20%. The review is devoted to modern concepts of etiology and pathogenesis of early pregnancy losses. Aim. Assess the role of epigenetic factors and molecular-genetic markers in the pathogenesis and prediction of early pregnancy losses Materials and methods. In order to write this review domestic and foreign publications were searched in Russian and international search systems (PubMed, eLibrary, etc.) for the last 10-15 years. Relevant articles from the peer-reviewed literature and clinical practice guidelines were included. Results. Many recent studies have proved the contribution of various epigenetic factors to the pathogenesis of spontaneous miscarriages, and the molecular-genetic determination such kinds of pregnancy complication has been confirmed. Conclusion. The miscarriage in early gestation is driven by combined impact of epigenetic and molecular-genetic factors, as well as the presence of intergenic interactions. It is may lead to deterioration of physiological functions, and maternal pathologenic pathways could be changed as during her periconceptional period as so during the pregnancy.


Author(s):  
Elena Korneeva ◽  
Mikhail Voevoda ◽  
Sergey Semaev ◽  
Vladimir Maksimov

Results of the study related to polymorphism of ACE gene (rs1799752)‎, integrin αIIbβ3, and CSK gene (rs1378942) influencing development of arterial hypertension in young patients with metabolic syndrome are presented. Hypertension as a component of the metabolic syndrome was detected in 15.0% of young patients. Prevalence of mutant alleles of the studied genes among the examined patients was quite high, so homozygous DD genotype was found in 21.6%, and mutant D allele of the ACE gene in 47.4%. A high risk of hypertension in patients with MS was detected in carriers of the T allele of the CSK (rs1378942) gene – 54.8%, which was most often observed in a combination of polymorphic ACE and CSK gene loci (p = 0.0053).


2017 ◽  
Vol 21 (3) ◽  
pp. 177-183
Author(s):  
Eman Morad ◽  
Mohamed Abd_ Elateef ◽  
Mohammad Mousa ◽  
Ismael Abdelatif

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