Serum Gastrin Levels Before and After 6 Weeks of Cimetidine Therapy in Patients with Duodenal Ulcer

Digestion ◽  
1977 ◽  
Vol 15 (3) ◽  
pp. 157-161 ◽  
Author(s):  
S. Bank ◽  
G.O. Barbezat ◽  
A.I. Vinik ◽  
C. Helman
Keyword(s):  
Duodenal Ulcer ◽  
Serum Gastrin ◽  
Before And After ◽  
Cimetidine Therapy

The Relation between Functioning Parietal Cell and Gastrin Cell Masses in Two Groups of Duodenal Ulcer Patients

1976 ◽  
Vol 50 (5) ◽  
pp. 375-383 ◽  
Author(s):  
D. J. Byrnes ◽  
Shiu Kum Lam ◽  
W. Sircus
Keyword(s):  
Duodenal Ulcer ◽  
Parietal Cell ◽  
Serum Gastrin ◽  
Acid Output ◽  
Ulcer Patient ◽  
Cell Mass ◽  
Inverse Correlation ◽  
Normal Subjects ◽  
Gastrin Cell ◽  
Before And After

1. Serum gastrin concentrations before and after a standardized meal were determined in twenty-eight patients with duodenal ulcer and in ten normal control subjects. 2. In response to pentagastrin, thirteen of the duodenal ulcer subjects secreted acid within the limits of normal and fifteen secreted in excess. 3. The differences in the basal serum gastrin concentrations between the three groups, normal subjects, acid ‘normosecretors’ and hypersecretors were not statistically significant but that of the hypersecretors was suggestively low. 4. The integrated gastrin response and peak gastrin responses to meals were higher in duodenal ulcer patients with normal acid secretion than in the hypersecretors but the values for the latter were not different from normal subjects. 5. Stabilization of intragastric pH by infusion into the antrum of sodium bicarbonate during the test meal response period did not alter these differences between the two ulcer patient groups. 6. A significant inverse correlation exists between the maximal acid output and the integrated gastrin response in both normal subjects and hypersecreting duodenal ulcer patients. 7. The evidence (a) supports the existence of an inverse relationship between the functioning parietal cell and gastrin cell masses, (b) shows the gastrin response in normosecreting ulcer subjects to be inappropriately high, and (c) suggests that excessive vagotonia exerts trophic effects upon both parietal cell mass and gastrin cell mass.

Serum Gastrin after 12 Months' Continuous Cimetidine Therapy for Duodenal Ulcer

1979 ◽  
Vol 9 (6) ◽  
pp. 637-638 ◽  
Author(s):  
J. Hansky ◽  
A. I. Stern ◽  
M. G. Korman ◽  
J. Waugh
Keyword(s):  
Duodenal Ulcer ◽  
Serum Gastrin ◽  
Cimetidine Therapy

Gastroesophageal Sphincter Pressure and Serum Gastrin Studies following Food Intake before and after Vagotomy for Duodenal Ulcer

1978 ◽  
Vol 13 (7) ◽  
pp. 885-889 ◽  
Author(s):  
A. Csendes ◽  
M. Öster ◽  
O. Brandsborg ◽  
J. Möller ◽  
M. Brandsborg ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Food Intake ◽  
Serum Gastrin ◽  
Sphincter Pressure ◽  
Before And After

Gastroesophageal Sphincter Pressure and Serum Gastrin Studies Following Food Intake before and after Vagotomy for Duodenal Ulcer

1978 ◽  
Vol 13 (4) ◽  
pp. 437-441 ◽  
Author(s):  
A. Csendes ◽  
M. Öster ◽  
O. Brandsborg ◽  
J. Möller ◽  
M. Brandsborg ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Food Intake ◽  
Serum Gastrin ◽  
Sphincter Pressure ◽  
Before And After

Serum gastrin and somatostatin levels in patients with gastric or duodenal ulcer

1988 ◽  
Vol 117 (4_Suppl) ◽  
pp. S180-S181
Author(s):  
M. PAWLIKOWSKI ◽  
D. CIEŚLAK ◽  
J. BERNER ◽  
K. RYBIŃSKI ◽  
S.M. WEBB ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Serum Gastrin

The effect of exercise, smoking and propranolol on serum gastrin in patients with duodenal ulcer and in vagotomized subjects

1978 ◽  
Vol 38 (5) ◽  
pp. 441-446 ◽  
Author(s):  
O. Brandsborg ◽  
N. J. Christensen ◽  
H. Galbo ◽  
M. Brandsborg ◽  
N. A. Lovgreen
Keyword(s):  
Duodenal Ulcer ◽  
Serum Gastrin
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