The Future: New Methods of Imaging Exploration in Alzheimer’s Disease

Author(s):  
Agneta Nordberg
Keyword(s):  
2020 ◽  
Vol 963 (9) ◽  
pp. 30-43
Author(s):  
M.Yu. Orlov

Studying the current state of cartography and ways of further developing the industry, the role of the map in the future of the society, new methods of promoting cartographic products is impossible without a deep scientific analyzing all the paths, events and factors influencing its formation and development throughout all the historic steps of cartographic production in Russia. In the article, the history of cartographic production in Russia is considered together with the development of private, state and military cartography, since, despite some differences, they have a common technical, technological and production basis. The author describes the stages of originating, formation and growth of industrial cartographic production from the beginning of the XVIII century until now. The connection between the change of political formations and technological structures with the mentioned stages of maps and atlases production is considered. Each stage is studied in detail, a step-by-step analysis was carried out, and the characteristics of each stage are described. All the events and facts are given in chronological order, highlighting especially significant moments influencing the evolution of cartographic production. The data on the volumes of printing and sales of atlases and maps by commercial and state enterprises are presented. The main trends and lines of further development of cartographic production in Russia are studied.


1990 ◽  
Vol 18 (1_part_1) ◽  
pp. 65-74
Author(s):  
John M. Frazier ◽  
Alan M. Goldberg

Biomedical endeavours can be divided into three major categories: research, education, and testing. Within the context of each of these categories, activities involving whole animals have made major contributions and will continue to do so in the future. However, with technological developments in the areas of biotechnology and computers, new methods are already reducing the use of whole animals in certain areas. This article discusses the general issues of alternatives and then focuses on the development of new approaches to toxicity testing.


F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 1459 ◽  
Author(s):  
Lukas M. Weber ◽  
Charlotte Soneson

Benchmarking is a crucial step during computational analysis and method development. Recently, a number of new methods have been developed for analyzing high-dimensional cytometry data. However, it can be difficult for analysts and developers to find and access well-characterized benchmark datasets. Here, we present HDCytoData, a Bioconductor package providing streamlined access to several publicly available high-dimensional cytometry benchmark datasets. The package is designed to be extensible, allowing new datasets to be contributed by ourselves or other researchers in the future. Currently, the package includes a set of experimental and semi-simulated datasets, which have been used in our previous work to evaluate methods for clustering and differential analyses. Datasets are formatted into standard SummarizedExperiment and flowSet Bioconductor object formats, which include complete metadata within the objects. Access is provided through Bioconductor's ExperimentHub interface. The package is freely available from http://bioconductor.org/packages/HDCytoData.


1916 ◽  
Vol 10 (3) ◽  
pp. 509-542 ◽  
Author(s):  
Salvador Rodríguez González

The members of the Central American Peace Conference, held at Washington in 1907, primarily intent upon devising all possible ways and means of maintaining permanent peace in the Isthmus, sought to introduce into the treaties which resulted from the Conference not only those means and recourses which experience had shown would preserve good understanding and harmony among the five states, but, more particularly, they endeavored to find new methods which would strengthen the desideratum of the Conference by eliminating the causes of civil or interstate wars which might in the future occur in the Central American countries.Naturally, the arsenal to which the Conference had to turn for the new arms to combat the causes of and prevent all war and revolution, could be none other than historical experience and the principles of international law.


2019 ◽  
Vol 5 (11) ◽  
pp. 84 ◽  
Author(s):  
Stefano Selci

The Special Issue on hyperspectral imaging (HSI), entitled “The Future of Hyperspectral Imaging”, has published 12 papers. Nine papers are related to specific current research and three more are review contributions: In both cases, the request is to propose those methods or instruments so as to show the future trends of HSI. Some contributions also update specific methodological or mathematical tools. In particular, the review papers address deep learning methods for HSI analysis, while HSI data compression is reviewed by using liquid crystals spectral multiplexing as well as DMD-based Raman spectroscopy. Specific topics explored by using data obtained by HSI include alert on the sprouting of potato tubers, the investigation on the stability of painting samples, the prediction of healing diabetic foot ulcers, and age determination of blood-stained fingerprints. Papers showing advances on more general topics include video approach for HSI dynamic scenes, localization of plant diseases, new methods for the lossless compression of HSI data, the fusing of multiple multiband images, and mixed modes of laser HSI imaging for sorting and quality controls.


Leonardo ◽  
2017 ◽  
Vol 50 (1) ◽  
pp. 84-85 ◽  
Author(s):  
Gina Czarnecki ◽  
John Hunt

This article presents the artwork Heirloom created by artist Gina Czarnecki and scientist John Hunt. Heirloom grows living portraits of Gina Czarnecki’s daughters from their own cells cultured from buccal swabs. The resulting artwork is an ongoing exploration in “culture,” “nurture” and “media” from the scientific, parental and artistic perspectives. The experiment is ongoing as new methods for sustaining life outside the lab have been developed for this work, potentially facilitating future DIY biotechnology for others and helping with maxillofacial reconstruction in the future. Heirloom has been presented within Trust Me, I’m an Artist, an EU Creative Europe supported project.


2002 ◽  
Vol 30 (2_suppl) ◽  
pp. 195-198
Author(s):  
Bernward Garthoff

An evaluation is presented of past experience of dialogue and collaboration between ECVAM and the European Federation of Pharmaceutical Industries and Associations (EFPIA) over the last nine years. Lessons learnt from the viewpoint of EFPIA company representatives are given. Also, proposals for the future ECVAM approach are made, such as support for other research areas for new methods to be validated, giving realistic statements to ECVAM's European Union and external customers, and being open to any new technology development that might help in opening and establishing new alternative avenues. Finally, the need for proper publications on the implementation of alternatives is recommended, for example, through the existing national platforms and their umbrella organisation, ecopa.


1975 ◽  
Vol 254 (1 Fifth Interna) ◽  
pp. 573-591 ◽  
Author(s):  
Ernst H. Beutner ◽  
Jau-Shyong Deng ◽  
Suyu Shu ◽  
Paul Andersen ◽  
Frans Peetoom
Keyword(s):  

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