Effect of Ligation of Left Pulmonary Artery at Birth on Maturation of Pulmonary Vascular Bed

Respiration ◽  
1962 ◽  
Vol 19 (5) ◽  
pp. 362-369
Author(s):  
Peter E. Pool ◽  
Keith H. Averill ◽  
John H.K. Vogel
Keyword(s):  
Pulmonary Artery ◽  
Left Pulmonary Artery ◽  
Vascular Bed ◽  
Pulmonary Vascular Bed

The pulmonary vascular bed in patients with functionally univentricular physiology and a Fontan circulation

2021 ◽  
pp. 1-10
Author(s):  
Ahmed Krimly ◽  
C. Charles Jain ◽  
Alexander Egbe ◽  
Ahmed Alzahrani ◽  
Khalid Al Najashi ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Venous Hypertension ◽  
Adult Survival ◽  
Vascular Reserve ◽  
Passive Flow ◽  
Vascular Bed ◽  
Systemic Ventricle ◽  
Pharmacologic Regulation ◽  
Fontan Palliation ◽  
Pulmonary Vascular Bed

Abstract Fontan palliation represents one of the most remarkable surgical advances in the management of individuals born with functionally univentricular physiology. The operation secures adult survival for all but a few with unfavourable anatomy and/or physiology. Inherent to the physiology is passive transpulmonary blood flow, which produces a vulnerability to adequate filling of the systemic ventricle at rest and during exertion. Similarly, the upstream effects of passive flow in the lungs are venous congestion and venous hypertension, especially marked during physical activity. The pulmonary vascular bed has emerged as a defining character on the stage of Fontan circulatory behaviour and clinical outcomes. Its pharmacologic regulation and anatomic rehabilitation therefore seem important strategic therapeutic targets. This review seeks to delineate the important aspects of pulmonary artery development and maturation in functionally univentricular physiology patients, pulmonary artery biology, pulmonary vascular reserve with exercise, and pulmonary artery morphologic and pharmacologic rehabilitation.

Pressure-Flow Relationships in the Dog Lung During Acute, Subtotal Pulmonary Vascular Occlusion

1958 ◽  
Vol 192 (3) ◽  
pp. 613-619 ◽  
Author(s):  
Michael T. Lategola
Keyword(s):  
Blood Flow ◽  
Pulmonary Artery ◽  
Pulmonary Artery Pressure ◽  
Pulmonary Blood Flow ◽  
Vascular Occlusion ◽  
Percentage Change ◽  
Artery Pressure ◽  
Vascular Bed ◽  
Change In Mean ◽  
Pulmonary Vascular Bed

The relationship of pulmonary artery pressure to pulmonary blood flow was studied in the dog by means of occlusive shifting of blood flow within the pulmonary vascular bed. All experiments were performed using the closed-chest preparation. The range of blood flow increases studied was 25–388%. A graphical plot of the percentage change in blood flow versus the percentage change in mean pulmonary artery pressure is presented. A visually estimated curve of this latter data is presented, discussed and compared to four other curves from previous pulmonary vascular studies. A comparison of these curves suggests that the relative maximum capacity of the pulmonary vascular bed of man and dog are similar. These curves plus certain assumptions allow the speculative delineation of a graphical area representing the ‘active’ vasomotor component of exercise at different levels of pulmonary blood flow increase.

scholarly journals OBSERVATIONS ON RESISTANCE TO THE FLOW OF BLOOD TO AND FROM THE LUNGS

1927 ◽  
Vol 45 (4) ◽  
pp. 655-671 ◽  
Author(s):  
Richmond L. Moore ◽  
Carl A. L. Binger
Keyword(s):  
Pulmonary Artery ◽  
Pulmonary Veins ◽  
Hydrogen Ion ◽  
Ion Concentration ◽  
Tissue Elasticity ◽  
Hydrogen Ion Concentration ◽  
Starch Grains ◽  
Vascular Bed ◽  
Shallow Breathing ◽  
Pulmonary Vascular Bed

1. Embolism of pulmonary arterioles and capillaries produced by the intravenous injection of starch grains results in a dilatation of the pulmonary artery and the right chambers of the heart. This has been demonstrated both by x-ray studies and direct inspection. 2. The dilatation of the pulmonary artery and heart occurs synchronously with the acceleration of respirations. 3. Dilatation of these structures produced by other means, such as obstruction to the flow of blood to and from the lungs, by gradually clamping either the pulmonary artery (cat and dog) or pulmonary veins (cat) does not, however, give rise to rapid and shallow breathing. 4. The effect of these maneuvers on respiration does not become apparent until respirations suddenly cease. 5. Neither does sudden restriction of the pulmonary vascular bed by clamping the left branch of the pulmonary artery give rise to rapid and shallow breathing, though this procedure may cause an increase in CO2 tension and in hydrogen ion concentration of the blood. 6. Since rapid and shallow breathing is not the result of (1) anoxemia, (2) increased pCO2 and hydrogen ion concentration of the serum, (3) restriction of pulmonary vascular bed by nearly half, (4) increase in resistance to the flow of blood to and from the lungs) (5) the presence of starch grains in the lungs acting as a local irritant, it must be the result of the secondary pathological changes which occur in the pulmonary parenchyma following embolism. 7. The nature of these changes, congestion and edema, has been discussed elsewhere. Whether they operate directly on nerve endings or through their influence on lung volume and tissue elasticity is not certain. 8. Various important clinical analogies have been emphasized.

scholarly journals Relationship Between the Pulmonary Artery Index and Physiological Properties of the Pulmonary Vascular Bed

1996 ◽  
Vol 60 (6) ◽  
pp. 334-340 ◽  
Author(s):  
Hideaki Senzaki ◽  
Hitoshi Kato ◽  
Michio Akagi ◽  
Toshio Hishi ◽  
Masayoshi Yanagisawa
Keyword(s):  
Pulmonary Artery ◽  
Vascular Bed ◽  
Physiological Properties ◽  
Pulmonary Vascular Bed

Unintended Pulmonary Artery Ligation during PDA Ligation

2016 ◽  
Vol 19 (4) ◽  
pp. 187 ◽  
Author(s):  
Dohun Kim ◽  
Si-Wook Kim ◽  
Hong-Ju Shin ◽  
Jong-Myeon Hong ◽  
Ji Hyuk Lee ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Ductus Arteriosus ◽  
Left Lung ◽  
Left Pulmonary Artery ◽  
Chest Ct ◽  
Mechanical Ventilator ◽  
Artery Ligation ◽  
Ventilator Support ◽  
Surgical Ligation ◽  
Emergent Operation

A 10-day-old boy was transferred to our hospital due to tachypnea. Patent ductus arteriosus (PDA), 4.8 mm in diameter, with small ASD was diagnosed on echocardiography. Surgical ligation of the ductus was performed after failure of three cycles of ibuprofen. However, the ductus remained open on routine postoperative echocardiography on the second postoperative day, and chest CT revealed inadvertent ligation of the left pulmonary artery (LPA) rather than the PDA. Emergent operation successfully reopened the clipped LPA and ligated the ductus on the same (second postoperative) day.<br />Mechanical ventilator support was weaned on postoperative day 21, and the baby was discharged on postoperative day 47 with a normal left lung shadow.

Ligation of left pulmonary artery instead of patent ductus arteriosus

2020 ◽  
Vol 30 (12) ◽  
pp. 1943-1945
Author(s):  
Semih Murat Yucel ◽  
Irfan Oguz Sahin
Keyword(s):  
Surgical Treatment ◽  
Pulmonary Artery ◽  
Patent Ductus Arteriosus ◽  
Surgical Complication ◽  
Ductus Arteriosus ◽  
Left Pulmonary Artery ◽  
Artery Ligation ◽  
Surgical Closure ◽  
Post Operative Period ◽  
Patent Ductus

AbstractDuctus arteriosus is an essential component of fetal circulation. Due to occurring changes in the cardiopulmonary system physiology after birth, ductus arteriosus closes. Patent ductus arteriosus can be closed by medical or invasive (percutaneous or surgical) treatment methods. Percutaneous or surgical closure of patent ductus arteriosus can be performed for the cases that medical closure failed. Surgical treatment is often preferred method for closure of patent ductus arteriosus in the neonatal period. The most common surgical complications are pneumothorax, recurrent laryngeal nerve injury, bleeding, and recanalisation. A very rare surgical complication is left pulmonary artery ligation that has been presented in a few cases in the literature. Echocardiography control should be performed in the early post-operative period, especially in patients with clinical suspicion. If reoperation is required, it should never be delayed. We report a newborn patient whose left pulmonary artery ligated accidentally during patent ductus arteriosus closure surgery and surgical correction of this complication at the early post-operative period.

scholarly journals Spontaneous pulmonary artery thrombus in a neonate

2021 ◽  
Vol 73 (1) ◽  
Author(s):  
Y. S. Shrimanth ◽  
Krishna Prasad ◽  
Adari Appala Karhtik ◽  
Parag Barwad ◽  
C. R. Pruthvi ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Respiratory Distress ◽  
Disease Risk ◽  
Maternal Diabetes ◽  
Left Pulmonary Artery ◽  
Pulmonary Angiography ◽  
Haemodynamic Instability ◽  
Artery Thrombosis ◽  
Heart Disease Risk Factors ◽  
Heart Disease Risk

Abstract Background Pulmonary artery thrombosis is rare in neonates and mimics as persistent pulmonary hypertension or congenital heart disease. Risk factors include septicemia, dehydration, polycythemia, maternal diabetes, asphyxia, and inherited thrombophilias. They present with cyanosis and respiratory distress. Careful echocardiogram assessment helps in identifying the thrombus in the pulmonary artery and its branches. Computed tomography pulmonary angiography confirms the diagnosis. Case presentation We present a case of term neonate who presented with respiratory distress and cyanosis and a detailed echocardiogram revealed thrombus in the origin of left pulmonary artery. The neonate was managed initially with unfractionated heparin and later with low molecular weight heparin with which there was significant resolution of the thrombus Conclusion Spontaneous pulmonary artery thrombosis though rare should be suspected in any cyanotic neonate with respiratory distress. Management in these cases depends on the haemodynamic instability and lung ischemia.

Type 2 bridging bronchus with left pulmonary artery sling

2021 ◽  
pp. 1-3
Author(s):  
Amna Al-Arnawoot ◽  
John Kavanagh ◽  
Elsie T. Nguyen
Keyword(s):  
Pulmonary Artery ◽  
Male Patient ◽  
Adult Male ◽  
Left Pulmonary Artery ◽  
Pulmonary Artery Sling ◽  
Bridging Bronchus ◽  
Left Pulmonary Artery Sling ◽  
Airway Anomalies ◽  
Adult Male Patient

Abstract Bridging bronchi are the rarest of the major airway anomalies reported in the literature. In this brief report, we present a case of a symptomatic adult male patient presenting with a type 2 bridging bronchus associated with left pulmonary artery sling.

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