Long-Term Control of Hyperparathyroidism in Advanced Renal Failure by Low-Phosphorus Low-Protein Diet Supplemented with Calcium (without Changes in Plasma Calcitriol)

Nephron ◽  
1995 ◽  
Vol 70 (3) ◽  
pp. 287-295 ◽  
Author(s):  
C. Combe ◽  
D. Morel ◽  
V. de Précigout ◽  
K. Blanchetier ◽  
J.L. Bouchet ◽  
...  
Nephron ◽  
1998 ◽  
Vol 79 (2) ◽  
pp. 148-153 ◽  
Author(s):  
Tatsuo Shiigai ◽  
Koji Hattori ◽  
Hitoshi Iwamoto ◽  
Akira Owada

Nutrients ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 1035 ◽  
Author(s):  
Chieh-Li Yen ◽  
Kun-Hua Tu ◽  
Ming-Shyan Lin ◽  
Su-Wei Chang ◽  
Pei-Chun Fan ◽  
...  

Background: A beneficial effect of a ketoanalogue-supplemented low-protein diet (sLPD) in postponing dialysis has been demonstrated in numerous previous studies. However, evidence regarding its effect on long-term survival is limited. Our study assessed the long-term outcomes of patients on an sLPD after commencing dialysis. Methods: This retrospective study examined patients with new-onset end-stage renal disease with permanent dialysis between 2001 and 2013, extracted from Taiwan’s National Health Insurance Research Database. Patients who received more than 3 months of sLPD treatment in the year preceding the start of dialysis were extracted. The outcomes studied were all-cause mortality, infection rate, and major cardiac and cerebrovascular events (MACCEs). Results: After propensity score matching, the sLPD group (n = 2607) showed a lower risk of all-cause mortality (23.1% vs. 27.6%, hazard ratio (HR) 0.77, 95% confidence interval (CI) 0.70–0.84), MACCEs (19.2% vs. 21.5%, HR 0.86, 95% CI 0.78–0.94), and infection-related death (9.9% vs. 12.5%, HR 0.76, 95% CI 0.67–0.87) than the non-sLPD group did. Conclusion: We found that sLPD treatment might be safe without long-term negative consequences after dialysis treatment.


Nephron ◽  
1998 ◽  
Vol 79 (2) ◽  
pp. 173-180 ◽  
Author(s):  
N. Soroka ◽  
D.S. Silverberg ◽  
M. Greemland ◽  
Y. Birk ◽  
M. Blum ◽  
...  

1995 ◽  
Vol 6 (5) ◽  
pp. 1379-1385
Author(s):  
J Coresh ◽  
M Walser ◽  
S Hill

Concerns have been raised about the possibility of protein restriction resulting in malnutrition and poor subsequent survival on dialysis. However, no studies have examined patients treated with protein restriction to determine their subsequent survival on dialysis. This study prospectively monitored 67 patients with established chronic renal failure (mean initial serum creatinine of 4.3 mg/dL) who were treated with a very low-protein diet (0.3 g/kg per day) supplemented with either essential amino acids or a ketoacid-amino acid mixture and observed closely for clinical complications. Forty-four patients required dialysis. Once dialysis was started, dietary treatment was no longer prescribed. The cumulative mortality rate during the first 2 yr after starting dialysis was 7% (95% confidence interval, 0 to 16%). During this period, only two deaths occurred compared with 11.5 deaths expected on the basis of national mortality rates adjusted for age, sex, race, and cause of renal disease (P = 0.002). However, the protective effect was limited to the first 2 yr on dialysis. Thereafter, mortality rates increased, resulting in a total of 10 deaths during 96.4 person-years of follow-up, which was not significantly lower than the 14.9 deaths expected (P = 0.25). Extrapolation of sequential serum creatinine measurements made before dietary treatment suggests that the improved survival cannot be due to the early initiation of dialysis. Although the lack of an internal control group and data on dialysis lends uncertainty, the large difference in mortality rate between these patients and the nationwide experience indicates that protein restriction and close clinical monitoring predialysis does not worsen and may substantially improve survival during the first 2 yr on dialysis. These findings point out the importance of studying predialysis treatments as a means for lowering mortality on dialysis.


Nephron ◽  
1975 ◽  
Vol 15 (6) ◽  
pp. 409-423 ◽  
Author(s):  
R. Bianchi ◽  
G. Mariani ◽  
A. Pilo ◽  
M.G. Toni

2009 ◽  
Vol 90 (4) ◽  
pp. 969-974 ◽  
Author(s):  
Philippe Chauveau ◽  
Lionel Couzi ◽  
Benoit Vendrely ◽  
Valérie de Précigout ◽  
Christian Combe ◽  
...  

AMB Express ◽  
2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Imtiaz Hussain Raja Abbasi ◽  
Farzana Abbasi ◽  
Mohamed E. Abd El-Hack ◽  
Ayman A. Swelum ◽  
Junhu Yao ◽  
...  

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