Long-Term Treatment with Low Protein Diet in Uremia

2015 ◽  
pp. 128-136 ◽  
Author(s):  
Per-Ola Attman
Keyword(s):  
Term Treatment ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Low Protein ◽  
Long Term Treatment

scholarly journals Does a Supplemental Low-Protein Diet Decrease Mortality and Adverse Events After Commencing Dialysis? A Nationwide Cohort Study

Nutrients ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 1035 ◽  
Author(s):  
Chieh-Li Yen ◽  
Kun-Hua Tu ◽  
Ming-Shyan Lin ◽  
Su-Wei Chang ◽  
Pei-Chun Fan ◽  
...  
Keyword(s):  
Protein Diet ◽  
Low Protein Diet ◽  
Research Database ◽  
Negative Consequences ◽  
Term Survival ◽  
Low Protein ◽  
All Cause Mortality ◽  
Stage Renal Disease ◽  
End Stage

Background: A beneficial effect of a ketoanalogue-supplemented low-protein diet (sLPD) in postponing dialysis has been demonstrated in numerous previous studies. However, evidence regarding its effect on long-term survival is limited. Our study assessed the long-term outcomes of patients on an sLPD after commencing dialysis. Methods: This retrospective study examined patients with new-onset end-stage renal disease with permanent dialysis between 2001 and 2013, extracted from Taiwan’s National Health Insurance Research Database. Patients who received more than 3 months of sLPD treatment in the year preceding the start of dialysis were extracted. The outcomes studied were all-cause mortality, infection rate, and major cardiac and cerebrovascular events (MACCEs). Results: After propensity score matching, the sLPD group (n = 2607) showed a lower risk of all-cause mortality (23.1% vs. 27.6%, hazard ratio (HR) 0.77, 95% confidence interval (CI) 0.70–0.84), MACCEs (19.2% vs. 21.5%, HR 0.86, 95% CI 0.78–0.94), and infection-related death (9.9% vs. 12.5%, HR 0.76, 95% CI 0.67–0.87) than the non-sLPD group did. Conclusion: We found that sLPD treatment might be safe without long-term negative consequences after dialysis treatment.

Effects of Long-Term Low Protein Diet on Albumin Metabolism in Chronic Uremia

Nephron ◽  
1975 ◽  
Vol 15 (6) ◽  
pp. 409-423 ◽  
Author(s):  
R. Bianchi ◽  
G. Mariani ◽  
A. Pilo ◽  
M.G. Toni
Keyword(s):  
Protein Diet ◽  
Low Protein Diet ◽  
Low Protein ◽  
Chronic Uremia

scholarly journals Long-term outcome on renal replacement therapy in patients who previously received a keto acid–supplemented very-low-protein diet

2009 ◽  
Vol 90 (4) ◽  
pp. 969-974 ◽  
Author(s):  
Philippe Chauveau ◽  
Lionel Couzi ◽  
Benoit Vendrely ◽  
Valérie de Précigout ◽  
Christian Combe ◽  
...  
Keyword(s):  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Keto Acid ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Low Protein ◽  
Very Low Protein Diet

scholarly journals Post-ruminal effects of rumen-protected methionine supplementation with low protein diet using long-term simulation and in vitro digestibility technique

AMB Express ◽  
2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Imtiaz Hussain Raja Abbasi ◽  
Farzana Abbasi ◽  
Mohamed E. Abd El-Hack ◽  
Ayman A. Swelum ◽  
Junhu Yao ◽  
...  
Keyword(s):  
Protein Diet ◽  
Low Protein Diet ◽  
In Vitro Digestibility ◽  
Low Protein ◽  
Methionine Supplementation

Maternal low-protein diet during lactation combined with early overfeeding impair male offspring’s long-term glucose homeostasis

Endocrine ◽  
2018 ◽  
Vol 63 (1) ◽  
pp. 62-69 ◽  
Author(s):  
Douglas Lopes Almeida ◽  
Fernando Salgueiro Simões ◽  
Lucas Paulo Jacinto Saavedra ◽  
Ana Maria Praxedes Moraes ◽  
Camila Cristina Ianoni Matiusso ◽  
...  
Keyword(s):  
Glucose Homeostasis ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Low Protein

Development of β-cell mass in fetuses of rats deprived of protein and/or energy in last trimester of pregnancy

2002 ◽  
Vol 283 (3) ◽  
pp. R623-R630 ◽  
Author(s):  
Eric Bertin ◽  
Marie-Noëlle Gangnerau ◽  
Georges Bellon ◽  
Danièle Bailbé ◽  
Annick Arbelot De Vacqueur ◽  
...  
Keyword(s):  
Control Diet ◽  
Cell Mass ◽  
Energy Restriction ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Restricted Diet ◽  
Β Cell ◽  
Fetal Plasma ◽  
Low Protein

Fetal malnutrition is now proposed as a risk factor of later obesity and type II diabetes. We previously analyzed the long-term impact of reduced protein and/or energy intake strictly limited to the last week of pregnancy in Wistar rats. Three protocols of gestational malnutrition were used: 1) low-protein isocaloric diet (5 instead of 15%) with pair feeding to the mothers receiving the control diet, 2) restricted diet (50% of control diet), and 3) low protein-restricted diet (50% of low-protein diet). Only isolated protein restriction induced a long-term β-cell mass decrease. In the present study, we used the same protocols of food restriction to analyze their short-term impact (on day 21.5 of pregnancy) on β-cell mass development. A 50% β-cell mass decrease was present in the three restricted groups, but low-protein diet, either associated or not to energy restriction, increased fetal β-cell insulin content. Among all the parameters analyzed to further explain our results, we found that the fetal plasma level of taurine was lowered by low-protein diet and was the main predictor of the fetal plasma insulin level ( r = 0.63, P < 0.01). In conclusion, rat fetuses exposed to protein and/or energy restriction during the third part of pregnancy have a similar dramatic decrease in β-cell mass, and their ability to recover β-cell mass development retardation depends on the type of malnutrition used. Moreover, our results support the hypothesis that taurine might play an important role in fetal β-cell mass function.

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